Find Your Next High-Paying Job in Pennsylvania

Are you a professional seeking $100K+ jobs in Pennsylvania? You've come to the right place. Ladders is your hub for high-paying Pennsylvania jobs across a broad range of industries, including Tech, Finance, Healthcare, and more.

Unlock Opportunities in Pennsylvania

Pennsylvania, known for its rich history and diverse job market, offers a plethora if opportunities for ambitious professionals seeking high-paying jobs.

How Ladders Can Help

Whether you're looking for jobs in Philadelphia, Pittsburgh, or smaller cities within Pennsylvania, Ladders has got you covered. Our selection of $100K+ jobs in Pennsylvania is carefully curated and regularly updated. Start your job searc on Ladders today!

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$78K - $95K *

Take ownership of security incident response, monitoring, analysis, and collaboration to safeguard our platform. Lead dynamic investigations, refine response protocols, and proactively mitigate threat...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$75K - $95K *

Shape the future of payment solutions by managing and analyzing credit card processing systems. Collaborate across teams to ensure compliance and enhance efficiency while delivering robust functionali...

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$175K - $230K *

Innovate the legal landscape by leading a dynamic team of transactional attorneys, focusing on revenue-generating contracts, enhancing strategic partnerships across departments, and driving operationa...

US-AnywhereRemote

Yesterday

  •   8 - 10 years exp.  •   Legal & Accounting

$143K - $196K *

Join our dynamic team to drive strategic marketing for innovative healthcare payment solutions. Leverage your expertise to create impactful messaging and collaborate with stakeholders, ensuring succes...

US-AnywhereRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$75K - $95K *

Contribute to drug product formulation and development within a dynamic team. Leverage your technical skills to execute experiments, coordinate activities, and solve challenges in a collaborative phar...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Join a team that's shaping the future of data center development in renewable energy. This role supports strategic partnerships and project advancement across U.S. power markets, ensuring commercial s...

US-AnywhereRemote

Reposted today

  •   Less than 5 years exp.  •   Real Estate & Construction

$198K - $219K *

Join a team that's shaping the future of CNS treatment through strategic financial leadership. Drive enterprise-wide planning and forecasting to support key investment decisions and enhance business p...

US-AnywhereRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$150K - $200K *

Transform sales performance by leading, coaching, and developing teams to achieve strategic growth objectives. Drive results through planning, a focus on talent acquisition, and a commitment to foster...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$159K - $204K *

Drive the compliance program for investment assets; partner with teams to ensure regulatory adherence, perform compliance testing, and enhance operational frameworks through strategic oversight and co...

Reposted today

  •   Less than 5 years exp.  •   Finance & Insurance

$250K - $250K+*

Join a dynamic research team to support clinical studies and data management. Collaborate directly with experienced scientists, participate in human subject research, and enhance your research skills...

Today

  •   Less than 5 years exp.  •   Healthcare

$88K - $95K *

Take ownership of the Accounts Receivable process by leading a team to ensure accurate invoicing, timely collections, and effective cash application, while driving process improvements and fostering c...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$170K - $227K *

Accelerate your leadership potential by driving strategic retirement benefits programs, ensuring compliance and optimizing financial wellness initiatives while collaborating across teams for effective...

US-AnywhereRemote

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$70K - $156K *

Elevate your career as a Site Reliability Engineer, driving operational excellence through innovative support strategies, critical issue resolution, and collaboration with global teams to ensure appli...

Today

  •   5 - 7 years exp.  •   Information Technology

$75K - $95K *

Support process control & automation systems, enhancing operational performance, product quality, and safety in manufacturing. Collaborate across teams to ensure stability and efficiency while executi...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$115K - $135K *

Lead the charge in managing complex tax engagements while providing strategic tax planning and advisory services to clients. Drive compliance, mentor your team, and enhance financial outcomes for busi...

Reposted today

  •   5 - 7 years exp.  •   Legal & Accounting

$140K - $190K *

Support global HR initiatives by standardizing policies and processes across markets, enhancing operational efficiency, and ensuring compliance with local laws, while guiding local teams to develop th...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Business Services

$90K - $120K *

Shape the future of global security and fraud management by leading policy development, supporting integration across systems, and advocating best practices to ensure compliance and strengthen organiz...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $113K *

Elevate the quality and compliance of critical R&D documents through meticulous QC checks and cross-functional collaboration, ensuring readiness for regulatory submission and supporting continuous pro...

US-AnywhereRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $120K *

Transform customer engagement by driving growth through targeted sales strategies, relationship management, and innovative solutions in the Liquid/Gas transmission market. Collaborate with teams to me...

Reposted today

  •   8 - 10 years exp.  •   Energy & Utilities

$100K - $130K *

Join our mission-driven team as the Cybersecurity Manager, where you will lead the development and implementation of a comprehensive cybersecurity program, driving compliance and enhancing organizatio...

Reposted today

  •   5 - 7 years exp.  •   Information Technology

$82K - $220K *

Drive your career with impactful financial analysis supporting program success. Collaborate cross-functionally to ensure contract execution meets national defense goals while maintaining budget and sc...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Aerospace & Defense

$80K - $90K *

Grow your career with a dynamic role in regulatory compliance. Drive advertising reviews, ensure adherence to federal and state laws, and collaborate with cross-functional teams to optimize compliance...

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$110K *

Reimagine enterprise systems with senior architecture expertise in VMware, Windows, and cloud infrastructure. Lead initiatives in modernization, security compliance, and automation to enhance hybrid e...

US-AnywhereRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$88K - $220K *

Drive the vision and strategy for innovative measurement products, enhancing client value and business growth through collaboration across teams, market insights, and scalable solutions in the healthc...

Reposted today

  •   8 - 10 years exp.  •   Healthcare

$100K - $155K *

Empower product security by integrating cybersecurity throughout development. Collaborate across teams to ensure robust security practices, manage vulnerabilities, and uphold compliance with automotiv...

US-AnywhereRemote

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

Frequently Asked Questions (FAQ)

  • What industries in Pennsylvania offer the most $100K+ jobs?question toggle

    There are numerous industries in Pennsylvania offering $100K+ jobs, including Tech, Finance, Healthcare, and more.

  • Can I find $100K+ jobs all over Pennsylvania on Ladders?question toggle

    Yes, Ladders list high-paying jobs in all areas of Pennsylvania including in big cities like Philadelphia and Pittsburgh, as well as smaller cities.

  • How often are the $100K+ job listings in Pennsylvania updated on Ladders?question toggle

    The $100K+ job listings in Pennsylvania are updated regularly to ensure that our users have access to the most current opportunities.