Find Your Next High-Paying Job in Pennsylvania

Are you a professional seeking $100K+ jobs in Pennsylvania? You've come to the right place. Ladders is your hub for high-paying Pennsylvania jobs across a broad range of industries, including Tech, Finance, Healthcare, and more.

Unlock Opportunities in Pennsylvania

Pennsylvania, known for its rich history and diverse job market, offers a plethora if opportunities for ambitious professionals seeking high-paying jobs.

How Ladders Can Help

Whether you're looking for jobs in Philadelphia, Pittsburgh, or smaller cities within Pennsylvania, Ladders has got you covered. Our selection of $100K+ jobs in Pennsylvania is carefully curated and regularly updated. Start your job searc on Ladders today!

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$180K - $215K *

Inspire regional growth by leading sales execution and building strong teams. Drive market entry and foster relationships to achieve performance goals in a fast-paced environment, ensuring compliance...

US-AnywhereRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Help us lead the design and integration of advanced network solutions, ensuring security and performance across enterprise environments. Drive innovation and operational efficiency through best practi...

3 days ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $145K *

Elevate your career by leading enterprise network architecture with a focus on security, scalability, and automation. Drive strategic leadership, manage complex integrations, and enhance operational e...

US-AnywhereRemote

4 days ago

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Drive workflow enhancement and data analytics as a Microsoft Power Platform Developer, integrating solutions to improve operational efficiency and real-time reporting across interconnected teams withi...

US-AnywhereRemote

2 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Grow a high-performing nursing team as you manage daily operations and foster patient care excellence. Lead by example in a collaborative environment while driving positive outcomes in behavioral heal...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $100K *

Champion high-impact psychological evaluations and assessments without the burnout of a traditional clinical role. Enjoy a structured schedule, no caseload, and focus solely on delivering meaningful s...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $180K *

Elevate your career by leading regional clinical sales efforts, coaching talent, and driving utilization growth through innovative strategies and strong cross-functional collaboration in a dynamic med...

US-AnywhereRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Accelerate account growth by managing a high-profile client relationship. Lead a skilled team, define business objectives, and implement innovative marketing strategies to achieve profitability and cl...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $100K *

Unlock potential by joining a compassionate veterinary team dedicated to high standards of care, advanced technology, and community connection. Enjoy flexibility and professional growth in a supportiv...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Own the strategy for Medical Weight Loss, driving multi-quarter roadmaps and aligning teams to achieve program goals while maintaining compliance and clinical integrity in a rapidly evolving healthcar...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$270K - $334K *

Advance medical strategies for rare diseases, leading significant projects that unify scientific expertise and business acumen. Collaborate with teams to spearhead launches, data generation, and KOL e...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a team that's dedicated to delivering technical excellence in pre-sales support. You will partner with sales to transform customer needs into tailored solutions and demos, ensuring alignment and...

US-AnywhereRemote

2 weeks ago

  •   5 - 7 years exp.  •   Technical Services

$227K - $341K *

Transform healthcare delivery by leading Medicare Advantage market expansions and enterprise technology implementations, ensuring compliance and operational success through effective governance and cr...

US-AnywhereRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Healthcare

$95K - $115K *

Join an established team providing exceptional women's health care in a dynamic, outpatient setting. Leverage your expertise as a Women's Health Nurse Practitioner to empower patients and enhance thei...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$85K - $105K *

Join a dynamic team to develop and optimize business rule logic, ensuring alignment with operational goals. Collaborate with multiple departments to identify and resolve technical limitations, fosteri...

US-AnywhereRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $135K *

Lead the charge in expert IT Operations support while managing complex issues, mentoring team members, and optimizing processes in a dynamic federal environment across a broad technology landscape...

US-AnywhereRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Information Technology

$191K - $263K *

Optimize the impact of medical writing by leading complex projects, managing teams, and ensuring compliance with regulatory standards, while contributing to the strategic growth of the organization in...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$170K - $250K *

Engage in cross-functional collaboration to lead disease awareness initiatives and drive the adoption of advanced cell therapies, enhancing treatment experiences for patients across diverse healthcare...

US-AnywhereRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$170K - $245K *

Join a team that's redefining machine learning initiatives to improve user outcomes. Leverage your expertise in ML, optimization, and software engineering to design scalable models, collaborate cross...

US-AnywhereRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$80K - $95K *

Transform the patient experience by leading operations and staff at a healthcare center, ensuring high-quality care and exceptional service while driving efficiency and collaboration among clinical te...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Transform payment processes by partnering with customers to enhance workflows, boost transaction volume, and drive revenue. Leverage your expertise in the payments landscape to deliver strategic insig...

US-AnywhereRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$88K - $114K *

Lead design and technical execution for healthcare projects, ensuring quality and sustainability while collaborating with clients and consultants. Drive successful outcomes through effective project m...

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$100K - $115K *

Unlock your potential as a Senior Analyst supporting 340B operations. Drive technical deployments, optimize program compliance, and mentor junior team members while working remotely and collaborating...

US-AnywhereRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Lead privacy risk assessments and AI governance initiatives across enterprise systems. Collaborate with Legal, Security, and stakeholders to ensure compliance with global privacy laws and mitigate ris...

US-AnywhereRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$164K - $282K *

Manage a pioneering AI science team to enhance knowledge accumulation and agentic learning for a cutting-edge R&D platform. Drive innovation, establish technical direction, and collaborate with expert...

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What industries in Pennsylvania offer the most $100K+ jobs?question toggle

    There are numerous industries in Pennsylvania offering $100K+ jobs, including Tech, Finance, Healthcare, and more.

  • Can I find $100K+ jobs all over Pennsylvania on Ladders?question toggle

    Yes, Ladders list high-paying jobs in all areas of Pennsylvania including in big cities like Philadelphia and Pittsburgh, as well as smaller cities.

  • How often are the $100K+ job listings in Pennsylvania updated on Ladders?question toggle

    The $100K+ job listings in Pennsylvania are updated regularly to ensure that our users have access to the most current opportunities.