Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Director of Data Science and Bioinformatics
$186K - $232K *
Innovate within a dynamic team by establishing bioinformatics capabilities, architecting scalable infrastructure, and enhancing genomic algorithms to drive excellence in women's and organ health produ...
Reposted 2 weeks ago
Executive Director, Global Learning
$173K - $312K *
Empower organizational growth by leading global learning strategies, aligning workforce capabilities with business goals, and driving innovative solutions. Collaborate with senior leaders to enhance l...
Reposted 4 days ago
Executive Director, Global Learning
$173K - $312K *
Elevate global learning initiatives by leading strategy, governance, and innovation. Collaborate with senior leaders to identify capability gaps and drive impactful learning solutions that align with...
2 weeks ago
$136K - $214K *
Lead the charge in optimizing revenue operations by managing a dynamic team, enhancing forecasting processes, and ensuring data integrity across systems. Collaborate closely with sales leadership to d...
2 days ago
$160K - $170K *
Join a team that's redefining production excellence by leading end-to-end photo and video shoots. You'll manage budgets, build partnerships, and create efficient workflows while ensuring brand integri...
1 week ago
Online Clinical Support Specialist
$92K - $138K *
Unlock your potential by joining a dynamic team focused on delivering top-notch Ultrasound IT support. Collaborate with customers to resolve complex technical issues in a fast-paced environment, ensur...
Reposted 1 week ago
$120K - $140K *
Drive product innovation in healthcare revenue cycle management by optimizing eligibility verification and enhancing payer connections. Collaborate with clients and internal teams to ensure effective...
Reposted 1 month ago
Software Engineer 4 - AI Native
$88K - $180K *
Accelerate progress at the forefront of AI-native software development. Drive engineering excellence by orchestrating autonomous agents and maintaining high-quality standards in a FedRAMP-authorized e...
4 weeks ago
$95K - $115K *
Elevate operational efficiency by leading shared service improvements and cross-functional collaboration to enhance patient and provider experiences while driving team performance and process excellen...
Reposted 3 weeks ago
Director Clinical Quality & Research Programs - Abdominal Wall Reconstruction & Hernia Center
$110K - $130K *
Drive strategic leadership in clinical quality and research programs, enhancing patient engagement and operational excellence. Oversee program development, compliance, and partnerships to foster innov...
2 weeks ago
Remote Evening Radiologist - IC
$250K - $300K *
Lead a dynamic team of radiologists in a remote setting, managing diverse caseloads including inpatient and outpatient cases. Enjoy a supportive culture with growth opportunities and a compensation mo...
1 week ago
$80K - $95K *
Optimize property performance through strategic maintenance leadership, driving safety culture and sustainability. This impactful role necessitates technical expertise and frequent travel to ensure ex...
3 weeks ago
Senior Client Solution Architect - Georgia (Remote)
$250K - $275K *
Lead multi-domain technical strategies and solutions, guiding clients to align technology with business goals. Mentor teams while owning solution architecture through the entire lifecycle, ensuring co...
3 weeks ago
Patient Nurse Navigator (RN) - Spine Center Clemmons
$79K - $118K *
Transform patient care by leading the Navigator Program, ensuring quality and efficiency in service delivery while fostering community relationships and continuous improvement in healthcare outcomes...
3 weeks ago
$110K - $130K *
Join a dynamic team as a strategic HR Business Partner, supporting global entities. Drive employee relations, performance management, and culture integration while guiding HR initiatives across divers...
Reposted 1 week ago
Home Health Registered Nurse (7 On/7 Off)
$77K - $106K *
Join a team that's dedicated to providing personalized home health care, managing patient recovery plans, and collaborating with healthcare professionals to enhance patient independence and well-being...
2 weeks ago
Remote Day General Radiologist - Coastal Radiology Associates
$500K+*
Join a team that's dedicated to providing high-quality radiology services. This fully remote role offers flexible scheduling, competitive compensation, and opportunities for partnership growth in a su...
1 week ago
Remote Day General Radiologist - Coastal Radiology Associates
$500K+*
Transform your career as a Remote General Radiologist, enjoying flexible daytime shifts and a supportive team. Join a progressive practice focused on clinical excellence and long-term growth, with opp...
1 week ago
$75K - $100K *
Empower innovation by developing secure web applications as a Full Stack Developer. Work collaboratively across frontend and backend components, enhancing functionalities while supporting mission-driv...
3 weeks ago
$70K - $110K *
Champion the B2B2C CRM strategy, driving engagement and retention while leading execution for key accounts. Balance hands-on Braze work with strategic oversight, coaching a CRM Manager to optimize per...
1 week ago
Senior Staff Environmental Engineer
$95K - $115K *
Elevate your career by providing engineering and consulting services for diverse environmental projects. Lead site investigations, design systems, and ensure compliance while collaborating with client...
3 weeks ago
Patient and Site Engagement Lead (US/UK)
$90K - $178K *
Transform the patient engagement landscape in clinical trials by developing and delivering strategic support initiatives. Partner with diverse stakeholders to enhance participation and optimize patien...
Reposted 3 days ago
$95K - $115K *
Drive excellence in pharmacy operations by ensuring accurate medication dispensing, compliance with regulations, and effective team leadership. Collaborate with healthcare professionals to enhance pat...
2 days ago
$125K - $150K *
Empower legal firms by leading the development of innovative IT solutions, driving market strategies, and enhancing service offerings. Collaborate with cross-functional teams to establish credibility...
2 days ago
$237K - $296K *
Join a team that's driving innovation in oncology by leading clinical development and medical affairs. Collaborate across functions to advance pivotal programs and ensure operational excellence in a f...
1 week ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.