Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$95K - $115K *

Empower partner success by managing relationships, enhancing product adoption, and driving engagement. Collaborate with cross-functional teams to deliver exceptional service and support, ensuring part...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$141K - $278K *

Engineer transformative HR solutions by leading ServiceNow HRSD implementations. Collaborate with cross-functional teams to design, develop, and deliver innovative HR services that enhance employee ex...

2 days ago

  •   5 - 7 years exp.  •   Business Services

$110K - $155K *

Champion roadway design initiatives by leading projects from concept to completion, mentoring junior engineers, and collaborating with clients to enhance transportation solutions for safer, connected...

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$110K - $155K *

Advance the future of transportation by leading roadway design projects, mentoring junior engineers, and collaborating with clients to deliver innovative solutions from concept to completion...

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$110K - $155K *

Lead roadway design projects from concept to completion, collaborating with clients and mentoring junior engineers. Drive innovative solutions in transportation, ensuring project success through effec...

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$80K - $95K *

Take ownership of the Nurse Manager role, overseeing patient safety operations, resource allocation, and compliance with care standards while leading a dedicated team and enhancing patient outcomes ac...

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$77K - $109K *

Support the NRI external sales team by identifying and nurturing opportunities to sell retirement products, while maintaining CRM data and collaborating on sales strategies to drive asset growth in a...

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$112K - $223K *

Lead global pharmacovigilance initiatives, ensuring compliance and operational excellence while guiding teams through complex safety reporting challenges across diverse therapeutic areas and trial pha...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Elevate your career by collaborating with cross-functional teams to enhance business operations, streamline processes, and drive value through effective analysis and documentation. Your expertise will...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$79K - $118K *

Join a dedicated team in providing exceptional patient care in a dynamic intermediate care unit, bridging critical care and general medical services while ensuring safety and therapeutic support for d...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$79K - $118K *

Champion comprehensive patient care by utilizing evidence-based practices and clinical expertise. Collaborate with healthcare teams to ensure safe, therapeutic environments for diverse patient populat...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $160K *

Join a team that's redefining healthcare sales by leading strategic initiatives, managing a high-performing team, and driving revenue growth in the Physical Therapy and Rehab markets. Shape the future...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Reimagine behavioral health services by providing strategic and operational leadership in an acute hospital setting, ensuring high-quality, patient-centered care while fostering collaboration with key...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to enhancing behavioral health services through strategic leadership, operational excellence, and community collaboration, ensuring high-quality, patient-centered care in...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$113K - $225K *

Pioneer digital adoption and workforce enablement by leading learning strategies for corporate systems, ensuring effective training, performance support, and stakeholder engagement across global platf...

RemoteRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Healthcare

$160K - $240K *

Champion the growth of PMCM services across multiple states, leading teams to enhance client relationships and drive revenue. Engage with transportation agencies to convert contracts into active proje...

2 days ago

  •   Less than 5 years exp.  •   Transportation

$100K - $120K *

Lead the charge in ensuring high-quality resident care by overseeing clinical compliance, enhancing healthcare services, and collaborating with community staff to promote the well-being and safety of...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$140K - $155K *

Deliver your expertise to enhance the security posture of Cloud Service Providers. Engage in comprehensive architecture reviews, compliance assessments, and technical consultations within a collaborat...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $165K *

Unlock potential by leading hydro turbine design and engineering projects, optimizing asset performance, and ensuring compliance with industry standards. Collaborate with cross-functional teams to enh...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$188K - $248K *

Shape the future of technology strategy consulting by guiding clients through complex IT transformations and strategic decisions, fostering strong relationships and delivering impactful solutions to e...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$160K - $200K *

Transform the operational landscape by leading a $40M business unit, ensuring excellence in engineering, production, and supply chain while driving safety, quality, and profitability through strategic...

5 days ago

  •   11 - 15 years exp.  •   Aerospace & Defense

$92K - $148K *

Transform clinical trial operations by leading site performance and delivery. Drive strategic initiatives, mentor teams, and ensure compliance while enhancing global trial objectives through local ins...

United StatesRemote

5 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$115K - $130K *

Grow and strengthen strategic relationships with healthcare systems to drive business success. Optimize networking and sales strategies to secure new contracts and expand our reach within the healthca...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Staffing

$125K - $150K *

Pioneer comprehensive ServiceNow solutions, leading implementations and mentoring teams. Drive architectural design, process automation, and integrations while ensuring optimal performance and governa...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$208K - $220K *

Drive enterprise leadership in clinical quality and regulatory readiness, ensuring consistent standards and governance across regions. Collaborate with stakeholders to translate quality insights into...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.