Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Regional Sales Director - Nashville
$180K - $215K *
Transform your career by leading regional sales efforts, driving product launch success, and building high-performing teams. Collaborate cross-functionally to achieve sales goals and foster strong cus...
4 days ago
Account Manager - Government Relations
$120K - $150K *
Join a dynamic team and drive mission success in government relations by managing relationships, orchestrating initiatives, and ensuring compliance in a fast-paced environment. Your expertise will dir...
Reposted 2 days ago
Senior Clinical Operations Manager, Canada/USA, remote
$110K - $130K *
Transform clinical operations by leading a dynamic team, ensuring high-quality trial management, and driving innovation through technology and AI solutions. Your strategic oversight will enhance perfo...
1 week ago
Senior Backend Engineer, Growth & MSSP
$170K - $235K *
Drive the design and implementation of backend services to enhance customer experiences across NodeZero’s licensing, provisioning, and admin systems. Lead efforts to ensure accuracy, scalability, and...
3 weeks ago
$176K - $230K *
Lead the charge in transforming healthcare through data-driven solutions. As a Senior Data Scientist, you'll spearhead projects that enhance patient outcomes, leveraging your expertise to align data s...
3 weeks ago
$115K - $125K *
Join a team that's focused on building and enhancing relationships with large managed care accounts. Utilize your expertise in account management to drive customer satisfaction, explore upselling oppo...
Reposted 3 days ago
Account Director, Promotional Medical Education
$100K - $120K *
Partner with us to drive strategic healthcare marketing initiatives. Lead client relationships, oversee peer-to-peer programs, and mentor team members to ensure compliance and achieve results while fo...
Reposted 1 week ago
Senior Director, Patient Reported Outcomes
$222K - $292K *
Elevate patient outcomes by leading global evidence strategies that showcase the value of therapies. Collaborate across functions to drive research programs, influence decision-making, and ensure scie...
2 weeks ago
$150K - $200K *
Lead the charge in delivering complex federal digital services programs, ensuring strategic direction, operational excellence, and strong customer relationships across multidisciplinary teams while ma...
2 days ago
Senior Consultant - Healthcare Compliance
$100K - $125K *
Empower healthcare compliance by enhancing programs, mitigating risks, and driving operational integrity. Collaborate with diverse clients to deliver tailored solutions in a dynamic regulatory landsca...
2 weeks ago
Senior Cybersecurity Analyst - SOC, Incident Response & Threat Hunting
$110K - $130K *
Lead proactive cybersecurity investigations, analyze threats, and enhance detection capabilities. Collaborate with teams to improve incident response and operational resilience while utilizing advance...
Yesterday
$80K - $95K *
Join a team that's dedicated to enhancing resident care through effective infection prevention and clinical services. Leverage your nursing expertise to lead initiatives that ensure safety and complia...
3 days ago
$117K - $160K *
Lead the charge in underwriting E&S commercial property and casualty accounts. Manage risk assessments, develop competitive quotes, and collaborate with carriers to optimize profitability while achiev...
3 days ago
Operations Standards Manager (Remote)
$80K - $95K *
Drive operational excellence by developing and maintaining standards, ensuring consistency across markets, and collaborating with cross-functional teams to enhance processes and documentation for opti...
1 week ago
$150K - $175K *
Shape exceptional user experiences by leading design for a unified legal platform. Drive user-centered solutions through research, collaboration, and design leadership to meet the complex needs of leg...
Reposted 3 weeks ago
Nurse Practitioner ((Bilingual) Spanish)
$90K - $110K *
Join a dynamic team of healthcare professionals to provide comprehensive patient care, including primary, urgent, and pain management services. Utilize your clinical skills to build relationships and...
5 days ago
Senior Site Activation Manager (US)
$107K - $213K *
Oversee site activation projects, ensuring timely delivery, effective communication, and compliance with regulations. Lead cross-functional teams to meet goals and address challenges, driving strategi...
Reposted 3 days ago
$85K - $100K *
Lead operations in a dynamic long-term care facility, ensuring regulatory compliance and high-quality resident care. Drive financial performance and foster a culture of accountability across departmen...
Reposted 3 weeks ago
Therapy Development Specialist - Northeast Region
$110K - $175K *
Accelerate patient care by optimizing therapy pathways and engaging key stakeholders. Collaborate with healthcare teams to enhance VTE awareness and program development, driving clinical initiatives a...
4 days ago
Executive Director, Patient Solutions Operations
$160K - $200K *
Lead the operational execution of a patient support program, ensuring high-quality service delivery and compliance. Drive strategic planning, team development, and continuous improvement initiatives t...
3 days ago
Executive Director, Patient Solutions Operations
$160K - $190K *
Drive operational excellence in patient support programs, enhancing access and outcomes through strategic leadership, compliance, and team development. Oversee key functions to ensure a patient-center...
4 days ago
Senior Consultant - Data Platforms & Architecture
$103K - $154K *
Unlock advanced data solutions by leveraging Microsoft Azure and Power BI. Collaborate with teams to deliver high-quality analytics and reporting, while enhancing business intelligence capabilities th...
4 days ago
Manager, Revenue Cycle Operations
$100K - $130K *
Join a dynamic team to lead and enhance billing and coding operations, ensuring quality and compliance across multiple markets. Drive performance, coach leaders, and collaborate cross-functionally to...
2 weeks ago
Psychiatric Nurse Practitioner - CA Virtual (FT)
$140K *
Join a team that's dedicated to delivering innovative mental health care through comprehensive evaluations and tailored treatment plans, utilizing advanced techniques in a collaborative, fast-paced en...
3 weeks ago
Hybrid Board Certified Behavior Analyst (BCBA) - Remote / In-Person
$90K - $100K *
Lead the delivery of high-quality ABA therapy in a hybrid role, balancing remote and in-person client engagement. Collaborate with clinical teams to develop individualized behavior plans and support f...
5 days ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.