Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
$83K *
Transform patient care by supervising staff and ensuring compliance with nursing standards. Collaborate with healthcare teams to enhance resident well-being and safety, while fostering a supportive en...
1 week ago
Nurse Practitioner (Bilingual (Spanish))
$90K - $110K *
Unlock potential by joining a dynamic team of healthcare providers, delivering comprehensive patient care in a busy outpatient setting. Engage in primary, urgent, and pain management services while fo...
5 days ago
Sr Architect, Professional Services
$160K - $200K *
Empower clients by leading the implementation of innovative solutions, ensuring successful adoption and integration of Omnissa Workspace ONE. Collaborate with diverse teams to drive business outcomes...
1 week ago
Physician, Internal Medicine - Telemedicine Opportunity - DrHouse
$210K *
Join a team that's redefining healthcare delivery through telemedicine. This role offers Internal Medicine physicians the chance to provide high-quality virtual care across North Carolina, balancing c...
3 days ago
Senior Data Analyst, Clinical Operations
$90K - $110K *
Optimize analytics workflows in Clinical Operations to enhance productivity and performance insights. Collaborate on data integration, reporting, and automation, ensuring actionable insights drive str...
Reposted 1 month ago
$110K - $130K *
Deliver innovative solutions by managing complex programs, ensuring seamless execution and coordination across multiple contracts while leveraging extensive IT expertise and leadership skills to drive...
Reposted 4 days ago
Associate Director - Technology, AI, & Digital Solutions - Healthcare
$150K - $250K *
Transform healthcare technology engagements by leading multidisciplinary teams, developing actionable strategies, and implementing AI and automation solutions to enhance operational efficiency and cli...
2 days ago
Senior Architect, Identity and Access Management (Saviynt)
$120K - $150K *
Drive the design and implementation of innovative Identity and Access Management solutions, enhancing security and user experience across cloud and on-premises environments while leading a team of IAM...
Reposted 3 days ago
Senior Research Economist - U.S. Health Policy
$166K - $203K *
Join a team that's tackling complex health policy issues through innovative research. Lead projects, mentor staff, and deliver actionable insights to clients while managing budgets and timelines in a...
1 week ago
$90K - $110K *
Optimize facility operations by leading a dedicated team, managing maintenance, ensuring safety compliance, and overseeing refurbishment projects, all while maintaining exceptional service standards a...
Reposted 3 weeks ago
$77K - $87K *
Champion strategic paid social initiatives, driving performance through data insights and collaboration across clients' portfolios, while ensuring continuous adaptation to market trends and platform i...
Reposted 3 weeks ago
Chief Clinical Officer (MD/ DO) - Value-based Primary Care
$250K - $300K *
Lead the charge in designing and implementing a scalable home-based care model, ensuring high-quality, patient-centered care through interdisciplinary collaboration and continuous improvement across d...
1 week ago
$120K - $145K *
Lead the charge in AI/ML initiatives that enhance student engagement and retention. Drive cross-functional collaboration to deliver predictive models and measurable outcomes, transforming data into ac...
2 weeks ago
$67K - $101K *
Join a dedicated team as you provide essential nursing care to patients in their homes, collaborating with healthcare professionals to ensure quality and continuity of care while adhering to regulatio...
6 days ago
Associate Principal Solution Architect
$177K - $279K *
Unlock potential by architecting customized applications using Conga Products. Lead end-to-end Quote-to-Cash implementations, enhancing operational efficiency and driving business transformation in co...
3 weeks ago
Field Clinical Manager (Remote)
$175K - $230K *
Empower healthcare innovation by leading a team of Field Clinical Specialists. Drive the successful launch of the Globe Pulsed Field System through training, support, and relationship-building with he...
1 week ago
Registered Nurse PRN Home Health
$71K - $107K *
Champion patient care by assessing needs, coordinating services, and supporting transitions. Collaborate with healthcare teams to enhance patient independence and health outcomes while supervising sup...
Yesterday
Associate Director, US Patient Advocacy
$164K - $225K *
Develop and execute patient advocacy strategies, engaging with PAOs and cross-functional teams to elevate the patient voice and ensure successful partnerships for rare disease therapeutic areas...
Reposted 2 days ago
Director, Biologics Process Development
$223K - $233K *
Deliver strategic leadership in biologics process development, overseeing outsourced manufacturing and ensuring alignment with corporate goals while driving technical excellence in late-stage developm...
3 weeks ago
$80K - $95K *
Lead the end-to-end recruiting process, enhancing strategies and partnerships across departments. Drive high-volume hiring with autonomy, ensuring a seamless candidate experience while collaborating c...
4 days ago
Manager, Partnerships & Network Development (West Coast)
$95K - $115K *
Lead and develop a high-performing team to expand behavioral healthcare access. Drive regional referral growth through strategic partnerships, data-driven decision-making, and effective outreach while...
3 days ago
PAM - Cyber Security Engineer III
$110K - $130K *
Lead the charge in advancing cyber security architecture for complex projects, ensuring safe and scalable IT solutions across multiple domains, including cloud computing, while developing strategic se...
1 month ago
Professional Education Manager
$110K - $130K *
Join a team that's dedicated to developing physician education programs that enhance scientific knowledge of cardiovascular therapies and ensure effective learning experiences for healthcare professio...
3 weeks ago
Sr. Director, Clinical Business Development
$180K - $258K *
Drive sales growth by strategizing expansion and nurturing key client relationships. Leverage data insights to optimize territory performance and collaborate with cross-functional teams to deliver tai...
1 month ago
Sr. Director, Clinical Business Development
$180K - $258K *
Advance business growth by driving strategic sales across regions, nurturing client partnerships, and orchestrating multi-functional solutions to enhance value and performance in the biopharmaceutical...
1 month ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.