Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$90K - $110K *

Support emergency healthcare delivery by performing clinical assessments, prescribing treatments, and coordinating patient care in a fast-paced environment. Collaborate with medical teams to ensure op...

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$160K - $200K *

Grow your career with a transformative leader shaping scalable patient support programs, guiding cross-functional initiatives, and driving operational excellence to enhance client satisfaction and org...

North Carolina, USRemote

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Deliver impactful sales leadership by managing a dynamic team, driving growth, and fostering key relationships within the healthcare community to achieve regional sales objectives and enhance professi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$66K - $113K *

Champion enterprise portfolio reporting and analytics, developing insights to drive strategic decision-making and enhance project visibility. Collaborate across teams to create actionable dashboards a...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$131K - $223K *

Transform federal child welfare initiatives by providing strategic leadership and oversight for a multi-million-dollar contract, ensuring effective management of technical assistance and stakeholder c...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Business Services

$120K - $160K *

Advance HR technology by leading Workday administration, ensuring optimal system performance, security, and data governance. Collaborate with HR and IT to deliver solutions that enhance business proce...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Staffing

$61K - $122K *

Transform clinical genetic curation by collaborating cross-functionally to enhance genomic testing, ensuring compliance with guidelines while supporting innovative health initiatives and improving pat...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Lead a high-performing team to manage comprehensive patient services, focusing on strategic operations, client relationships, and compliance. Ensure program performance meets KPIs while driving contin...

North Carolina, USRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$184K - $396K *

Shape the future of healthcare technology by leading clinical informatics initiatives, enhancing patient outcomes, and driving enterprise-wide Epic optimization within a dynamic team of experts dedica...

RemoteRemote

1 month ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive high-quality therapy services as a Director of Rehabilitation, overseeing operations and fostering a collaborative environment in a skilled nursing facility. Empower therapists to enhance reside...

Yesterday

  •   Less than 5 years exp.  •   Transportation

$250K - $300K *

Champion innovative radiology practices to enhance patient care and operational efficiency alongside a dynamic team. Drive clinical excellence and leverage technology to elevate standards across healt...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $112K *

Join us in designing user-centered digital experiences that enhance support for warriors and their families. Collaborate across teams to transform insights into engaging solutions, ensuring accessibil...

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $115K *

Lead a dynamic team of licensed therapists, providing exceptional patient care and clinical excellence in a supportive environment with flexible scheduling and modern facilities...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$350K - $375K *

Lead the charge in defining and implementing a modern AI architecture across multiple business units, ensuring scalable, efficient, and secure AI systems that enhance product capabilities and drive in...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$155K - $259K *

Elevate your career by leading integrated optimization programs that enhance clinical, operational, and financial performance for healthcare clients. Drive measurable outcomes while managing diverse m...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$82K - $115K *

Transform the academic landscape by leading faculty development and student engagement. Drive excellence in teaching and support strategies while managing faculty performance and fostering a collabora...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$70K - $215K *

Unlock potential by owning full-cycle recruiting for diverse tech roles, utilizing cutting-edge AI tools to streamline processes, enhance candidate experience, and influence hiring strategies in a fas...

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$111K - $150K *

Join us to deliver comprehensive psychological services that enhance readiness and resilience. Provide evaluations, diagnosis, and treatment while collaborating with interdisciplinary teams to support...

1 week ago

  •   Less than 5 years exp.  •   Information Technology

$111K - $150K *

Take ownership of delivering comprehensive psychological services to enhance readiness and well-being. Collaborate with interdisciplinary teams to provide evidence-based care, conduct evaluations, and...

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$111K - $150K *

Drive psychological health and performance by providing comprehensive evaluations, diagnoses, and treatments. Collaborate with interdisciplinary teams to enhance readiness and resilience, delivering e...

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$174K - $218K *

Reimagine healthcare by shaping partnerships that drive innovative virtual-first care solutions. As a Senior Product Manager, you will bridge product and commercial teams, enhancing member engagement...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $100K *

Empower pet families through compassionate mobile veterinary care, focusing on dignity and comfort. Deliver exceptional end-of-life services, building meaningful connections in a collaborative, respec...

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $95K *

Empower healthcare technology by enhancing clinical systems and integrations. Collaborate with IT and business stakeholders to optimize workflows, manage projects, and ensure system performance across...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $200K *

Join a team that's shaping the future of self-funded health plans by drafting and negotiating critical contracts. Collaborate with cross-functional teams to ensure compliance and drive business succes...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$241K - $337K *

Transform your career with a flexible role in primary care, serving a diverse patient population. Collaborate with a dedicated team in a supportive environment, offering both part-time and full-time o...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.