Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$150K - $200K *

Engage in leading a dynamic team dedicated to delivering top-notch offensive security engagements, ensuring delivery quality and client satisfaction, while collaborating with sales to expand accounts...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Transform enterprise network architecture by leading LAN migration projects, ensuring seamless transitions to Cisco SDA fabric. Collaborate with cross-functional teams to execute plans, manage changes...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$180K - $220K *

Engage with healthcare services and technology leaders to drive new business growth. Leverage a robust support system to build relationships, execute territory plans, and expand existing accounts whil...

United StatesRemote

5 days ago

  •   8 - 10 years exp.  •   Healthcare

$85K - $95K *

Join as a critical team member to manage and enhance productivity platforms, ensuring stability, security, and user satisfaction. Collaborate across teams to drive operational maturity and navigate co...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$250K - $275K *

Empower your career as a Senior Client Solutions Architect, guiding clients through complex tech implementations. Lead solution strategy from design to execution while mentoring technical teams and co...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$74K - $107K *

Drive comprehensive patient care as an RN Care Manager, coordinating assessments, care plans, and transitions in a collaborative environment to enhance patient outcomes and support their healthcare jo...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$130K - $196K *

Unlock the potential of data by leading statistical design and analysis across the product lifecycle. Collaborate with cross-functional teams to drive evidence generation and ensure scientific integri...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $196K *

Drive statistical leadership across the product lifecycle, collaborating with cross-functional teams to define objectives and analysis strategies. Ensure scientific integrity and provide actionable in...

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $210K *

Drive impactful projects as a Power Platform Consultant, collaborating with a dynamic team to deliver innovative solutions for high-profile clients while advancing your career with cutting-edge techno...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Information Technology

$95K *

Drive exceptional dining experiences in a vibrant community. Lead a dedicated team, manage budgets, and collaborate with culinary experts to create memorable meals that enhance residents' lives in a s...

2 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$242K - $303K *

Join as the primary privacy leader to manage and enhance an enterprise-wide privacy program while navigating complex regulations. Collaborate across departments to drive compliance, innovation, and ef...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Shape the future of cancer care technology by leading data strategy and operations. Drive AI adoption, collaborate with cross-functional teams, and architect a robust platform that enhances personaliz...

RemoteRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Unlock your potential by supporting pharmacovigilance processes, managing ICSR activities, and ensuring compliance with regulations. Collaborate with a global team to enhance safety management and con...

Raleigh, NCRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive excellence in pharmacovigilance by managing ICSR processes, ensuring compliance, and supporting project teams. Collaborate with global colleagues to enhance safety reporting and contribute to cl...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $150K *

Lead the charge in driving impactful cybersecurity and AI risk programs, managing multidisciplinary teams, and translating complex findings into executive insights while fostering client relationships...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$160K - $190K *

Champion healthcare transformation by leading client partnerships and driving growth across a portfolio of health system accounts. Spearhead strategic initiatives, enhance renewals, and unlock expansi...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$89K - $148K *

Partner with us to design and implement secure architectures for enterprise environments, ensuring compliance with regulatory frameworks and cybersecurity best practices through expert collaboration a...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Business Services

$100K - $120K *

Drive network expansion by engaging providers and negotiating contracts to enhance Medicare services. Collaborate with a remote team to ensure network adequacy and build strong relationships with heal...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $115K *

Empower your career by managing a clinical team to oversee patient care needs and ensure quality service delivery. Collaborate with care providers, support clients, and drive performance in a remote s...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$94K - $139K *

Join a team that's dedicated to enhancing communication and quality of life. As a Speech Language Pathologist, you'll provide essential therapy services, collaborate with healthcare professionals, and...

6 days ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $125K *

Transform our Care Team operations by leading workforce planning and strategy. Collaborate across departments to optimize resource allocation while ensuring quality care delivery as we scale effective...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $140K *

Lead and inspire a nursing center team, ensuring compliance and high-quality care. Drive financial performance, engage staff, and enhance community relations while fostering a compassionate environmen...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$69K - $105K *

Elevate your research career by conducting impactful studies that enhance crisis services. Collaborate with experts to analyze data, develop tools, and contribute to vital evaluations that support the...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$99K - $110K *

Join a team that's committed to providing impactful psychological assessments and care. You'll leverage your expertise to develop treatment plans while collaborating with multidisciplinary professiona...

1 month ago

  •   Less than 5 years exp.  •   Healthcare

$108K - $169K *

Champion pediatric development by delivering impactful therapy in children's natural environments. Collaborate with families and interdisciplinary teams to foster independence and confidence in every...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.