Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Forward Deployed Engineer (Technical Architect)
$170K - $210K *
Empower Federal agencies by architecting and delivering AI-assisted software solutions. Responsible for client engagement, technology integration, and ensuring that production-ready solutions meet ope...
3 weeks ago
Home Health Speech Language Pathologist
$85K - $117K *
Empower patients by delivering personalized speech therapy services in home settings. Collaborate with healthcare teams to develop treatment plans, assess progress, and enhance communication skills, e...
Yesterday
Physician, OB/GYN - Telemedicine Opportunity - DrHouse
$210K *
Elevate patient health by delivering comprehensive virtual OB/GYN care. Manage diverse clinical cases via telemedicine while ensuring work-life balance and providing compassionate support across North...
1 month ago
$120K - $150K *
Elevate pediatric dental care by joining our collaborative team, where you'll provide exceptional treatment to children in a supportive, high-volume practice. Enjoy a fulfilling role that fosters last...
Yesterday
$120K - $144K *
Join a team that's dedicated to providing exceptional dental care to children. This role offers the chance to build lasting relationships in a supportive, multi-doctor environment while utilizing mode...
Yesterday
Registered Nurse Care Manager, VBC
$80K - $90K *
Drive patient-centered care by collaborating with nephrology practices to enhance outcomes for high-risk CKD and ESKD patients through outreach, education, and care coordination in various settings...
Today
Vice President Field Operations
$172K - $223K *
Champion operational excellence as a strategic leader, driving performance and financial results across the PacWest Region while ensuring safety, quality, and compliance in a mission-driven environmen...
6 days ago
Strategy and Operations Physician Enterprise Clinical SME
$125K - $235K *
Drive operational excellence in healthcare by leading transformative initiatives, optimizing workflows, and enhancing provider productivity. Collaborate with teams to deliver data-driven solutions tha...
Yesterday
Associate Medical Director, Clinical Research
$225K - $281K *
Join a team that's pushing the boundaries of oncology research! This key role involves designing and leading clinical trials, ensuring data integrity, and collaborating with global experts to advance...
3 weeks ago
Associate Medical Director, Clinical Research
$225K - $281K *
Explore your career in clinical development as you design and lead innovative oncology studies, ensuring data integrity and compliance while collaborating with cross-functional teams and cultivating r...
3 weeks ago
$200K - $215K *
Advance the cloud platform capabilities, ensuring secure, reliable, and scalable product delivery while enhancing developer experience and shaping reliability practices in a mission-driven healthcare...
3 weeks ago
$110K - $130K *
Lead the charge in strategic decision-making and daily operations, ensuring quality and cost-effectiveness while fostering community relations and promoting organizational goals through effective mana...
2 weeks ago
$110K - $130K *
Support clients in maximizing their Workday investment by implementing and enhancing Adaptive Planning solutions. Drive project success through relationship building, best practices, and exceptional s...
3 weeks ago
$90K - $110K *
Engage in comprehensive patient care as a Nurse Practitioner, collaborating with physicians to implement treatment plans, mentor staff, and ensure high-quality medical services in an integrated care t...
2 days ago
Ambulatory Surgery Center Administrator/DON
$110K - $130K *
Drive the strategic direction and operational performance of our Ambulatory Surgery Center, ensuring high-quality patient care, financial sustainability, and compliance with regulatory standards while...
Reposted 3 weeks ago
Senior Network Medical Director, West Region
$184K - $396K *
Lead our clinical strategy in the West Region, driving performance in cost, quality, and member experience through partnerships with healthcare providers. Collaborate with teams to enhance value-based...
Reposted 6 days ago
Senior Staff Platform Engineer
$135K - $160K *
Reimagine cloud infrastructure as you build and operate scalable systems that empower product teams. Ensure reliability and speed in a dynamic environment, supporting enterprise-scale solutions for Fo...
Today
Senior or Principal Practice Leader - Environmental Engineer or Geoscienist
$110K - $130K *
Join a team that's shaping the future of environmental engineering. Lead diverse projects, drive business development, and mentor professionals while ensuring compliance and client satisfaction across...
3 days ago
Associate Director, Thought Leader Liaison, Oncology - Central
$157K - $256K *
Champion strategic engagements with oncology thought leaders to enhance insights and drive initiatives for our Solid Tumor portfolio, focusing on collaboration across teams and executing regional stra...
4 days ago
NeuroPsych Account Specialist - Hawaii HI
$123K - $168K *
Explore the potential of Neurocrine products by managing key accounts, driving sales growth, and fostering relationships with healthcare professionals. Collaborate cross-functionally to enhance produc...
3 weeks ago
Sr. Engineer, AI Cyber Security
$140K - $187K *
Innovate the future of AI security by designing and implementing robust defenses against adversarial threats, ensuring the integrity of AI systems while fostering innovation and collaboration across c...
2 weeks ago
$109K - $144K *
Reimagine healthcare technology as an Application Analyst supporting Epic Professional Billing. Leverage your expertise in revenue cycle operations to optimize billing accuracy and enhance workflow ef...
4 weeks ago
$160K - $180K *
Join us to lead our accounting operations, ensuring accuracy and scalability. Drive financial reporting, audits, and team development while applying your technical expertise in a dynamic, multi-channe...
2 weeks ago
Senior Security Consultant, Application Security
$75K - $175K *
Advance application security initiatives by leading manual code reviews, penetration tests, and threat modeling. Work closely with clients to strengthen their secure development processes, delivering...
Reposted 2 weeks ago
Licensed Clinical Social Worker (LCSW, LCMHC, LMFT) Ballantyne Office
$80K - $115K *
Transform patient care by joining our dedicated team of therapists. Enjoy flexible scheduling, competitive compensation, and a supportive environment while making a meaningful impact on diverse popula...
3 weeks ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.