Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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$102K - $133K *

Unlock potential by optimizing clinical systems and driving informatics initiatives. This role combines strategy with hands-on support across EHR applications, fostering collaboration to enhance workf...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K *

Drive new business growth by owning the full sales cycle in SMB and Mid-Market segments. Build relationships, strategize territory plans, and deliver compelling proposals to meet client needs while ex...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$250K - $300K *

Lead the charge in transforming cardiovascular care. Oversee clinical teams, ensuring high standards, build partnerships, and shape value-based care strategies to improve patient outcomes and provider...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $190K *

Empower our sales team by driving strategic growth in key accounts. Leverage your expertise in Enterprise SaaS to navigate complex sales in the Life Sciences sector, fostering partnerships and deliver...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$110K - $130K *

Transform customer IT service requirements into innovative solutions that enhance loyalty and profitability. Lead technical resources in delivering high-quality financial industry solutions while ensu...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$104K - $120K *

Unlock your potential as an SLP providing remote speech therapy. Collaborate with educators, develop IEPs, and support student success in a flexible environment tailored for diverse learning needs...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$210K - $250K *

Drive excellence in inpatient psychiatry by leading comprehensive behavioral health services, enhancing care quality, and ensuring effective collaboration among multidisciplinary teams while overseein...

1 month ago

  •   5 - 7 years exp.  •   Healthcare

$174K - $374K *

Engage with patients in their homes to conduct health evaluations, build relationships, and bridge care gaps. This role demands extensive travel and flexibility to provide personalized care and diagno...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$140K - $190K *

Join a team that's transforming clinical trials through advanced data science. Drive the development of predictive models and machine learning algorithms to enhance patient enrollment and trial manage...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Manage IT projects to implement M365 solutions for diverse clients, ensuring successful execution of project goals and fostering collaboration between teams...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $160K *

Lead the management of privacy risks and regulatory compliance while providing expert guidance on AI-related legal issues to cross-functional teams in a dynamic healthcare environment. Drive privacy i...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$82K - $132K *

Champion the future of clinical documentation education by developing and implementing training for healthcare providers. Collaborate with teams to enhance quality metrics and ensure compliance with d...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $230K *

Join a dynamic team as you lead engineering efforts to develop an AI Patient Engagement Agent, transforming clinical trials by automating patient interactions and enhancing operational efficiency for...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Drive healthcare transformation by leading advanced consulting initiatives, enhancing delivery systems, and improving health outcomes. Collaborate with clients and stakeholders to implement strategic...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$128K - $176K *

Transform complex clinical and regulatory documents into clear, compliant submissions. Collaborate with teams to ensure accuracy and adherence to standards while managing multiple projects in a fast-p...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$330K - $390K *

Join a team that's driving enterprise-level strategic statistical leadership across Biostatistics. You'll oversee programs, mentor statisitians, and ensure collaboration for successful drug developmen...

United StatesRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Transform virtual primary care by delivering exceptional patient care in a collaborative environment. Join a dedicated team for a 5-month full-time opportunity, enhancing your skills while making a me...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Partner with us to drive sales in the Neurosurgery product line, achieving revenue targets through strategic planning, relationship building, and exceptional customer service in a dynamic operating ro...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Unlock potential by joining a dynamic team of healthcare providers in a busy outpatient practice, delivering comprehensive primary, urgent, and specialty care while fostering strong patient relationsh...

4 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$90K - $110K *

Drive patient care excellence in a dynamic outpatient setting, blending primary, urgent, and pain management services. Collaborate with a dedicated team to enhance patient relationships and ensure con...

5 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$80K - $100K *

Take ownership of complex desktop and mobile device support, ensuring high customer satisfaction. Administer enterprise management platforms and collaborate with teams to deliver effective technology...

RemoteRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $100K *

Transform endpoint management by leading complex support initiatives, ensuring seamless service delivery across diverse environments. Collaborate with teams to enhance user experience and optimize tec...

RemoteRemote

4 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Shape the future of recruitment by building a market strategy, developing client relationships, and managing the full recruitment lifecycle to drive success and revenue growth in a dynamic environment...

United StatesRemote

6 days ago

  •   Less than 5 years exp.  •   Staffing

$80K - $115K *

Join a team that's dedicated to transforming lives through therapy. We seek Licensed Therapists to provide exceptional care to diverse populations, fostering growth and healing in a supportive environ...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $115K *

Join a team that's dedicated to providing exceptional therapy services to diverse populations. Collaborate with a skilled clinical team to enhance mental health outcomes for adults and youth, ensuring...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.