Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$108K - $144K *

Elevate your career by leading paleontological projects, mentoring teams, and driving business development. Utilize your expertise to navigate complex environmental compliance challenges across North...

2 weeks ago

  •   8 - 10 years exp.  •   Business Services

$120K - $135K *

Champion the growth of partnerships in the public safety sector, harnessing your sales expertise to cultivate high-level relationships, create member benefits, and drive innovative solutions that enha...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$148K - $190K *

Join us to lead user experience design on our innovative learning platform. You'll own the design end-to-end, establishing a design system, shaping navigation, and enhancing the student experience thr...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$144K - $240K *

Champion software quality by leading Verification & Validation efforts for autonomous labs, creating automated tests and ensuring seamless integration with hardware systems for rapid development...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $216K *

Transform program administration for a large federal services initiative, overseeing workforce planning, financial operations, and compliance. Collaborate with diverse teams to enhance operational eff...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$80K - $95K *

Shape the future of healthcare revenue management by leading IDR processes, ensuring compliance, and driving data-informed improvements while mentoring a team of analysts to optimize workflows and enh...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$90K - $140K *

Shape the future of biotechnology by driving growth for innovative cell counting solutions. Collaborate with key account managers to enhance customer experiences and manage complex sales processes acr...

Today

  •   Less than 5 years exp.  •   Healthcare

$170K - $200K *

Elevate our Enterprise business by building impactful relationships with brokers and consultants. Drive engagement strategies, generate new business opportunities, and enhance BetterHelp's presence in...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$155K - $410K *

Lead the charge in transforming healthcare payer operations through data science, driving strategic initiatives, and enhancing member experiences while guiding teams to deliver actionable insights and...

Yesterday

  •   8 - 10 years exp.  •   Legal & Accounting

$166K - $200K *

Empower clinical innovation by leading complex development programs, ensuring high-quality data and compliance. Collaborate cross-functionally to drive scientific strategy and enhance product developm...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Advance the adoption of cutting-edge prostate cancer imaging solutions while leading site activations, enhancing workflows, and ensuring optimal product utilization in the oncology sector, supporting...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Advance your career by leading the harmonization and standardization of product transfer processes across global regions, ensuring compliance and quality in manufacturing operations while partnering w...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $190K *

Champion growth by developing and executing strategic sales plans for tech-enabled services in the state and local government sector, driving client engagement and exceeding sales quotas through relat...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$75K - $90K *

Drive impactful healthcare solutions by fostering relationships with physicians, hospitals, and community partners. Leverage creativity and strategic planning to enhance service delivery in hospice ca...

3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$180K - $275K *

Unlock potential by defining and driving the technical vision and product strategy for Next-Gen SIEM and Log Management products, ensuring alignment with market needs and customer motivations while fo...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$88K - $105K *

Lead the logistics strategy for critical defense programs, ensuring seamless support and operational readiness. Collaborate with cross-functional teams to develop and execute comprehensive plans that...

1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$127K - $212K *

Champion secure architecture by conducting reviews and assessments for cloud and on-premise systems. Leverage your cybersecurity expertise to design solutions that align with security best practices a...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Business Services

$125K - $150K *

Shape data-driven solutions by leveraging your expertise in machine learning and analytics. Collaborate with cross-functional teams to deliver impactful insights and ensure seamless deployment in prod...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$110K - $130K *

Design and implement AI solutions by rapidly prototyping applications, transforming ideas into scalable production models. Collaborate with clients, stakeholders, and teams to deliver innovative techn...

3 weeks ago

  •   Less than 5 years exp.  •   Business Services

$150K - $195K *

Empower quality assurance excellence by leading GMP oversight for contract manufacturing and validation projects, ensuring compliance and collaboration across technical operations to support drug deve...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Manage implementation projects, ensuring clear ownership and accountability across complex customer engagements while maintaining rigorous oversight of critical paths and deliverables for timely launc...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$85K - $100K *

Transform healthcare analytics by supporting ACOs in the MSSP program. Leverage data-driven insights to track performance metrics, optimize risk scores, and collaborate with teams to enhance value-bas...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$122K - $163K *

Empower clinical development through scientific leadership in biomarker and bioanalytical strategies, guiding assay design, CRO oversight, and regulatory submissions in a fast-paced environment...

Reposted yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $170K *

Drive business growth by building relationships and delivering innovative solutions in the Higher Education sector. Leverage your expertise in sales and strategic transformation to meet client needs a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$230K - $255K *

Accelerate state government affairs strategies to enhance patient access and foster relationships with key stakeholders. Collaborate cross-functionally to navigate legislative landscapes and advocate...

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.