Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$130K - $160K *

Join a team that's advancing radiopharmaceuticals by leading formulation and manufacturing efforts. Collaborate with experts to ensure product quality and regulatory compliance while driving innovativ...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$88K - $105K *

Join a team that's dedicated to enhancing patient care in a dynamic urgent care environment. As a vital clinical collaborator, you'll lead triage, manage patient flow, and implement nursing interventi...

1 week ago

  •   Less than 5 years exp.  •   Staffing

$110K - $115K *

Innovate testing strategies and enhance software quality through automated and manual verification. Collaborate across teams to ensure compliance and optimize processes while leveraging AWS and full-s...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $100K *

Empower People Operations by optimizing processes across the employee lifecycle. Collaborate cross-functionally to enhance efficiency, drive improvements, and maintain high-quality HR services while s...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$175K - $210K *

Drive the enterprise data strategy and governance, ensuring data quality, compliance, and accessibility. Lead cross-functional teams to foster a data-rich culture, enabling advanced analytics and AI r...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$112K - $140K *

Partner with us to drive renewal retention and premium preservation by managing a high-volume portfolio, ensuring timely renewals, and serving as the primary contact for agents. Leverage your expertis...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Finance & Insurance

$80K - $95K *

Accelerate your career by leading a nursing home facility, ensuring high-quality care, financial success, and compliance with regulations. Collaborate with department heads to foster a positive enviro...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$164K - $280K *

Champion modern frontend architecture by leading a cross-team initiative to enhance clinical applications, ensuring scalability, quality, and consistency through React, GraphQL, and Node.js in a colla...

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$95K - $115K *

Engage with clients to transform complex Enterprise Architecture needs into actionable solutions. Manage implementation workstreams, ensuring effective onboarding and training while fostering strong r...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$140K - $200K *

Drive the execution of innovative clinical trials in a fast-paced biotech environment, ensuring compliance and effective collaboration with teams to meet study objectives and timelines across diverse...

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$170K - $190K *

Champion innovative technical solutions as you lead the architecture and implementation on cutting-edge projects. Collaborate with clients and cross-functional teams to ensure successful delivery and...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $225K *

Elevate the consumer healthcare experience by building and scaling innovative web applications. Collaborate across teams to tackle operational challenges while ensuring technical excellence and a seam...

2 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$75K - $125K *

Support our team by providing exceptional administrative assistance, managing complex calendars, and facilitating client engagement. Your proactive approach will enhance efficiency and collaboration a...

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$64K - $100K *

Lead the charge in managing conflicts of interest for lateral candidates, conducting thorough research and analysis to support risk management initiatives while collaborating with teams to ensure comp...

1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$235K - $300K *

Elevate patient care by leading educational initiatives for clinicians on advanced neurotoxin therapies. Utilize your expertise in spasticity and cervical dystonia to enhance training programs and sup...

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$105K - $130K *

Join a team that's redefining billing solutions in the legal sector. Leverage your expertise in law firm financial operations to support sales efforts, conduct client demos, and enhance our innovative...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$250K - $290K *

Elevate your career by joining a leading Family Medicine practice offering competitive compensation, flexible schedules, and robust support. Contribute to excellence in patient care within a thriving...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$94K - $120K *

Lead the strategic direction of managed services portfolios, ensure high-quality outcomes, and drive customer satisfaction while partnering across functions to align services with innovations and need...

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$150K - $180K *

Lead global clinical operations to ensure timely delivery of complex clinical studies, fostering collaboration, and driving patient engagement while managing budgets and compliance effectively...

4 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$142K - $195K *

Pioneer innovative technology strategies that align business vision with IT execution. Collaborate across teams to drive enterprise architecture modernization and deliver impactful solutions while men...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Join a team that's dedicated to optimizing EHR systems, enhancing workflows, and supporting healthcare professionals by building and maintaining tailored applications for effective patient care and op...

RemoteRemote

4 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$88K - $134K *

Shape the future of customer success by leading the deployment of IoT solutions for enterprise clients. Your role will bridge sales and strategy, ensuring clients maximize the value of their technolog...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$150K - $180K *

Transform architecture strategy in a leading healthcare organization, driving innovation and collaboration across IT infrastructure while ensuring alignment with business and regulatory standards...

Massachusetts, USRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Staffing

$420K - $476K *

Elevate your career by driving Employer Sales growth, shaping go-to-market strategies, and building a high-performing sales organization. This strategic role requires strong leadership and expertise i...

United StatesRemote

Reposted 2 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$80K - $104K *

Partner with us to deliver high-quality oral and maxillofacial surgical care in a supportive environment. Enjoy clinical autonomy, strong referral relationships, and modern facilities while advancing...

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.