Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$195K - $341K *

Empower healthcare delivery by leading clinical reviews, provider education, and quality improvement initiatives. Collaborate with teams to enhance member care standards and support compliance with re...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$92K - $138K *

Join us as a Clinical Application Specialist, leveraging your expertise in maternal-infant care to deliver training and support for digital healthcare solutions. Collaborate with teams to enhance clin...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$226K - $310K *

Support and advise Global Human Resources on strategic employment law matters, managing compliance, investigations, and workforce strategies across diverse global regions to mitigate risks and promote...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$85K - $95K *

Transform the lives of children with autism by leading a dedicated team, designing personalized treatment plans, and collaborating with families and professionals to ensure high-quality ABA services a...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

Empower clients by leading the implementation of innovative solutions, ensuring successful adoption and integration of Omnissa Workspace ONE. Collaborate with diverse teams to drive business outcomes...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$90K - $110K *

Optimize analytics workflows in Clinical Operations to enhance productivity and performance insights. Collaborate on data integration, reporting, and automation, ensuring actionable insights drive str...

RemoteRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Partner with us to enhance our analytics workflows, integrating diverse data sources to drive insights for clinical operations leadership. You'll streamline reporting processes, ensuring data quality...

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$134K - $269K *

Advance enterprise consulting by driving revenue and client success. Oversee engagements, optimize resource management, and ensure delivery excellence across multi-phase projects to elevate market pre...

Reposted 4 days ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Deliver innovative solutions by managing complex programs, ensuring seamless execution and coordination across multiple contracts while leveraging extensive IT expertise and leadership skills to drive...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $250K *

Transform healthcare technology engagements by leading multidisciplinary teams, developing actionable strategies, and implementing AI and automation solutions to enhance operational efficiency and cli...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Business Services

$87K - $107K *

Deliver optimal health outcomes by facilitating care for complex healthcare needs, using clinical skills and managed care principles. Collaborate with a dedicated team to authorize necessary services...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$150K - $245K *

Drive your career forward by leading clinical strategy and execution in genetics medicine. Collaborate with cross-functional teams to translate genetic insights into innovative treatments, making a me...

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$268K - $302K *

Lead strategic clinical pharmacology initiatives, guiding drug development from early to late stages. Collaborate cross-functionally, ensuring robust pharmacological strategies and regulatory complian...

Cambridge, MARemote

Reposted yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$77K - $87K *

Champion strategic paid social initiatives, driving performance through data insights and collaboration across clients' portfolios, while ensuring continuous adaptation to market trends and platform i...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$250K - $300K *

Lead the charge in designing and implementing a scalable home-based care model, ensuring high-quality, patient-centered care through interdisciplinary collaboration and continuous improvement across d...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$120K - $145K *

Lead the charge in AI/ML initiatives that enhance student engagement and retention. Drive cross-functional collaboration to deliver predictive models and measurable outcomes, transforming data into ac...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$187K - $253K *

Shape the future of regulatory technology by leading strategic initiatives that enhance compliance, efficiency, and insight-driven operations across Regulatory Affairs and Medical Writing, ensuring se...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$249K - $308K *

Champion cross-functional R&D programs, driving strategy and execution for drug development. Lead teams through milestones, ensuring alignment with corporate objectives while managing risks and foster...

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$177K - $279K *

Unlock potential by architecting customized applications using Conga Products. Lead end-to-end Quote-to-Cash implementations, enhancing operational efficiency and driving business transformation in co...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$175K - $230K *

Empower healthcare innovation by leading a team of Field Clinical Specialists. Drive the successful launch of the Globe Pulsed Field System through training, support, and relationship-building with he...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$167K - $191K *

Unlock potential by leading HEOR/RWE initiatives, collaborating with cross-functional teams to drive evidence generation and strategic insights that inform clinical practice and access in oncology, en...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Lead strategic patient marketing initiatives for NF1 PN, overseeing agency relationships and driving engagement through omnichannel execution. Collaborate cross-functionally to enhance patient outreac...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$164K - $225K *

Develop and execute patient advocacy strategies, engaging with PAOs and cross-functional teams to elevate the patient voice and ensure successful partnerships for rare disease therapeutic areas...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$130K - $152K *

Design and implement enterprise identity solutions, focusing on Microsoft Entra. Drive identity security and governance across hybrid environments, ensuring compliance and operational excellence while...

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$126K - $204K *

Elevate patient care by collaborating with physicians and healthcare teams to manage treatment plans for patients with hematologic malignancies, ensuring comprehensive support and quality improvement...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.