Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$75K - $100K *

Elevate your career as a therapist with flexible scheduling options, including hybrid and telehealth opportunities. Join a supportive team that values your expertise and offers competitive compensatio...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $215K *

Develop and lead regional strategies to drive product launch success, ensuring alignment with corporate goals. Build a high-performing team, foster customer relationships, and execute data-driven deci...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$220K - $240K *

Lead patient marketing initiatives to enhance engagement and awareness for a rare disease community. Collaborate with cross-functional teams to develop strategies that drive brand perception and suppo...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$108K - $145K *

Empower project delivery excellence by managing complex client engagements, mentoring team members, and driving process improvements. Collaborate with stakeholders to achieve revenue targets while ens...

3 days ago

  •   5 - 7 years exp.  •   Information Technology

$245K - $335K *

Join a team that's redefining drug discovery by leading business operations across technology and national security. Drive accountability, build metrics, and empower teams to deliver impactful results...

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$232K - $290K *

Lead the charge in optimizing workforce operations and analytics for multi-condition health care services. Develop strategies for capacity planning, staffing, and analytics to drive efficiency and sup...

United StatesRemote

Reposted 3 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$93K - $99K *

Shape the future of patient care by leading the MDS assessment process, developing individualized care plans, and ensuring compliance with regulations in a skilled nursing environment. Drive quality o...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$93K - $99K *

Elevate patient care by leading the MDS process and developing tailored care plans. Collaborate with healthcare teams to ensure compliance with regulations while enhancing resident outcomes in a skill...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$142K - $185K *

Pioneer strategic HR initiatives to enhance corporate functions and build leadership capabilities. Collaborate across departments to anticipate talent needs, shape organizational design, and drive wor...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$100K *

Transform lives by empowering clients through personalized fitness programs. Leverage your passion for wellness to manage your schedule, foster client relationships, and develop professionally within...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$109K - $164K *

Drive advanced digital forensics and incident response initiatives while mentoring a skilled engineering team. Leverage deep technical knowledge to enhance operational capabilities and ensure exceptio...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Champion innovative solutions as a Senior Implementation Project Manager, leading complex software implementations and driving customer success through effective project management and collaboration a...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Information Technology

$175K - $250K *

Join a team that's optimizing medical cost management and driving financial performance across Commercial lines. Leverage your expertise in healthcare economics to influence strategic contracting and...

United StatesRemote

4 days ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Drive your career as a Compliance Architect, guiding clients through CMMC compliance journeys. Collaborate with stakeholders to assess risks, develop strategic roadmaps, and ensure alignment with regu...

RemoteRemote

Reposted today

  •   8 - 10 years exp.  •   Information Technology

$76K - $148K *

Play a key role in managing clinical trials, ensuring compliance and quality oversight of project deliverables while collaborating with cross-functional teams to meet timelines and budget goals...

RemoteRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Manage a comprehensive EHR portfolio, ensuring alignment with strategic goals and facilitating communication among stakeholders while promoting project governance and reporting for improved decision-m...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Staffing

$75K - $90K *

Join a team that's dedicated to providing personalized, skilled nursing care in home settings. Enjoy autonomy, strong support, and the opportunity to build meaningful relationships with patients while...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$74K - $137K *

Engage stakeholders to deliver innovative training programs on Direct Tax Compliance solutions. Collaborate with teams to enhance learning experiences through various formats, ensuring alignment with...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Media

$74K - $137K *

Elevate your career by delivering expert training in Direct Tax Compliance solutions, enhancing customer success through engaging learning experiences. Collaborate with teams to create impactful conte...

RemoteRemote

3 weeks ago

  •   Less than 5 years exp.  •   Media

$100K - $120K *

Transform preclinical research by leading innovative in vivo and in vitro pharmacology studies. Collaborate with biotech partners to design experiments, analyze data, and mentor junior staff within a...

4 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $115K *

Shape the future of psychiatric nursing by enhancing care management and compliance. Collaborate with leadership to support clinical operations, training, and quality improvement initiatives, ensuring...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$79K - $97K *

Join a team that's dedicated to optimizing HR operations through hands-on support of Dayforce HCM and iCIMS. Leverage your expertise in HRIS to enhance processes, troubleshoot issues, and drive compli...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Real Estate & Construction

$130K - $190K *

Drive the design and operation of robust AI systems, leading technical delivery and guiding teams in building high-throughput pipelines and production services that enhance customer engagement across...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$130K - $190K *

Shape the future of AI by building scalable AI agents that drive innovation across healthcare applications, fostering collaboration with diverse teams to implement advanced solutions and ensure operat...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Hospitality & Recreation

$125K - $150K *

Transform technology operations by leading IT and cybersecurity strategies, ensuring secure, scalable systems while enhancing employee support in a dynamic, remote-first environment. Collaborate acros...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Food & Beverages

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.