Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$120K - $145K *

Transform patient care by providing comprehensive services to diverse populations. Collaborate with healthcare teams to diagnose, treat, and educate patients while maintaining accurate medical records...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$126K - $140K *

Shape the future of customer success by owning technical onboarding, guiding clients through implementation, optimizing deployments, and ensuring adherence to best practices for optimal use of the pla...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Empower individuals by delivering tailored, evidence-based psychotherapy remotely to older adults. Collaborate with a supportive team while managing your schedule and focusing on patient care, aided b...

Massachusetts, USRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $150K *

Elevate operational excellence by leading strategic initiatives and financial management across multiple institutions. Collaborate with senior leadership to drive goals, enhance partnerships, and ensu...

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$250K - $300K *

Partner with us to provide expert breast imaging interpretation in a fully remote setting. Enjoy flexible scheduling and a supportive team environment while contributing to exceptional patient care ac...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$85K - $130K *

Champion change in healthcare IT consulting by leading enterprise software projects and enhancing organizational workflows. Collaborate with leadership, drive client success, and deliver impactful res...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$110K - $141K *

Pioneer excellence in program management by leading large-scale Healthcare IT initiatives. Collaborate with C-suite stakeholders to ensure strategic delivery, financial performance, and risk managemen...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$205K - $341K *

Lead the charge in Global Patient Safety, overseeing safety strategies and cross-functional collaboration to ensure optimal drug development and patient safety across therapeutic areas...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$205K - $341K *

Join a team that's shaping the future of patient safety by leading global strategies and cross-functional collaborations to ensure optimal safety support for innovative therapies. Make a meaningful im...

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$190K - $225K *

Shape the future of healthcare by driving strategic KOL engagement and insight generation in rare neurology. Collaborate with thought leaders to influence brand strategy and enhance patient outcomes t...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Join a team that's transforming healthcare by supporting robotic systems in clinical settings. You'll empower users through training and technical expertise, ensuring safe and effective adoption of in...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Join a team that's pivotal in advancing robotic minimally invasive care. You'll support early users, provide technical expertise during procedures, and collaborate with engineering teams to enhance sy...

Boston, MARemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$148K - $246K *

Champion healthcare legal compliance and investigations, partnering with senior leadership to navigate complex regulatory landscapes. Utilize expertise in healthcare laws to ensure integrity while sup...

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$76K - $116K *

Transform lives as you provide quality nursing care in a dynamic environment, developing tailored care plans to enhance resident well-being while collaborating with a multidisciplinary team focused on...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$136K - $187K *

Join a team that's dedicated to empowering patients with generalized Myasthenia Gravis through education and support. As a key point of contact, you'll coordinate care, provide resources, and ensure c...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$280K - $340K *

Transform regulatory strategy and operations across CMC and clinical activities, leading a high-performing team to ensure compliance and successful product approvals from development through post-appr...

United StatesRemote

3 weeks ago

  •   15+ years exp.  •   Information Technology

$180K - $200K *

Drive market adoption and revenue growth in nephrology and transplant sectors. Leverage expert relationships and strategic business plans to promote innovative genetic diagnostic tools and enhance chr...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$135K - $150K *

Join a team that's dedicated to improving patient outcomes through expert pharmacy care. Collaborate with healthcare professionals to ensure safe medication practices and provide compassionate support...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K - $95K *

Advance patient care by providing evidence-based ABA services as a BCaBA, collaborating within a multidisciplinary team to support children's developmental needs while ensuring flexible scheduling and...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Innovate clinical quality systems for scalable care delivery, ensuring standards meet payer expectations and driving measurable performance improvements across independent health providers...

RemoteRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Deliver impactful sales leadership by managing a dynamic team, driving growth, and fostering key relationships within the healthcare community to achieve regional sales objectives and enhance professi...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$66K - $113K *

Champion enterprise portfolio reporting and analytics, developing insights to drive strategic decision-making and enhance project visibility. Collaborate across teams to create actionable dashboards a...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$274K - $457K *

Shape the future of hematology clinical development by leading study teams, ensuring regulatory compliance, and guiding strategic initiatives. Your expertise will shape innovative therapies that signi...

Reposted 5 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$131K - $223K *

Transform federal child welfare initiatives by providing strategic leadership and oversight for a multi-million-dollar contract, ensuring effective management of technical assistance and stakeholder c...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Business Services

$140K - $171K *

Shape investor relations and corporate communications strategies, ensuring effective engagement with stakeholders. Collaborate to execute communication plans, analyze investor trends, and manage inves...

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.