Find $100K+ Jobs in Massachusetts

Explore professional opportunities across Massachusetts with Ladders. Browse vetted jobs paying $100,000 or more, from roles in Boston and Cambridge to opportunities in Worcester, Springfield, and other communities throughout the state. Whether you’re pursuing your next leadership position or advancing your career in a specialized field, discover openings that match your experience and goals.

Explore Massachusetts Career Opportunities

Massachusetts is home to a diverse economy with employers in technology, healthcare, financial services, education, biotechnology, manufacturing, and professional services. Job availability and compensation vary by employer, role, and experience. Use Ladders to explore current openings and identify opportunities aligned with your skills.

Search by Location and Specialty

Focus your search on major employment centers such as Boston, Cambridge, and Worcester, or look across the state for roles that fit your preferences. Refine your search by job title, industry, seniority, and other relevant criteria to find opportunities suited to your career direction.

Advance Your Career with Ladders

Ladders specializes in vetted professional jobs paying $100,000 or more. Review listings, compare role requirements, and apply to positions that align with your qualifications. Set up a complete profile and keep your resume current to make it easier to pursue your next Massachusetts opportunity.

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$313K - $391K *

Lead the safety and risk management activities for investigational and marketed products, providing expert guidance and oversight within a collaborative, matrix team environment, while ensuring compli...

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Drive evidence-based healthcare improvements by leading evaluations and strategic analyses. Collaborate with multidisciplinary teams to enhance Military Health System outcomes through expert consultat...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$208K - $250K *

Lead the charge in clinical development, overseeing trials and cross-functional teams to ensure high-quality data supports product strategy. Drive innovative research while ensuring compliance and fos...

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$125K - $165K *

Drive your career with a dynamic role focused on maximizing sales in dermatology. Engage with healthcare providers, build relationships, and promote innovative therapies to enhance patient outcomes in...

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $125K *

Optimize radiology solutions by analyzing workflows, enhancing clinical efficiency, and guiding stakeholders in implementing DeepHealth technologies for improved diagnostic outcomes and user adoption...

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$114K - $131K *

Drive the coordination and delivery of psychiatric care within a correctional facility, ensuring continuity and safety in treatment. Collaborate with multidisciplinary teams to enhance patient outcome...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$190K - $225K *

Transform relationships with key opinion leaders in rare neurological diseases, providing strategic insights and guidance to inform brand strategies and enhance engagement across medical and commercia...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$85K - $87K *

Drive impactful early intervention services by coordinating treatment plans and outreach for clients, collaborating with a multidisciplinary team to enhance child development and family support in a d...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in executing therapy access strategies, collaborating with internal teams to enhance patient access. Drive process improvements, mentor junior staff, and analyze payer trends to optimi...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$104K - $145K *

Join a team that's dedicated to enhancing children's lives through behavioral therapy. Provide in-home support and interventions for youth, while collaborating with families to foster understanding an...

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$94K - $119K *

Transform the lives of patients by providing tailored occupational therapy. Collaborate with a multidisciplinary team to enhance mobility and independence in a supportive environment, while advancing...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$94K - $119K *

Advance patient care by conducting assessments, developing treatment plans, and collaborating with healthcare teams. This role emphasizes a 1:1 treatment model, supporting individuals with diverse cha...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$173K - $205K *

Shape the future of neurology by leading in vivo pharmacology studies, collaborating with cross-functional teams, and driving data-driven decisions for IND submissions in a dynamic biotech environment...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Champion a data transformation journey, driving architectural innovation and modernizing technology stacks, while solving complex data issues in a collaborative, high-impact environment with broad cro...

United StatesRemote

Reposted 4 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$80K - $95K *

Join a team that's shaping the future of AI solutions by deploying and integrating cutting-edge technologies. Collaborate with customers and engineers to enhance system performance and drive innovatio...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$115K - $120K *

Join a team that's dedicated to supporting clients through relationship and family challenges. As a licensed clinician, you'll manage your own cases, provide therapy via telehealth, and ensure compreh...

Medford, MARemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $120K *

Empower clients by providing expert therapy in a remote setting, focusing on relationship and family dynamics. Manage your own caseload, make clinical decisions, and maintain accurate records to suppo...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $120K *

Transform lives as a Licensed Marriage and Family Therapist, providing remote therapy to individuals, couples, and families. Help clients navigate challenges and foster healthier relationships through...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$115K - $120K *

Join a team that's dedicated to enhancing family dynamics through remote therapy. You'll provide support to clients, develop tailored treatment plans, and track progress, all while working in a flexib...

Worcester, MARemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$210K - $250K *

Grow your career by providing comprehensive diagnostic radiology services, including consultations and interpretations for a diverse patient population. Collaborate remotely to ensure timely and accur...

United StatesRemote

4 days ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$196K - $342K *

Drive the Quality organization for the VET Platform, overseeing strategic initiatives and managing teams. Collaborate cross-functionally to enhance product quality and processes, ensuring compliance a...

Reposted today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $115K *

Unlock potential by providing vital sales support and presentations, driving customer integration and product utilization, while conducting market research to enhance offerings. Collaborate closely wi...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $115K *

Drive technical and sales support for sales teams, enhancing customer integration and product use to secure new business while troubleshooting existing products effectively. Engage with clients to ali...

Reposted 3 days ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Join a team that's redefining telehealth by delivering exceptional psychotherapy to older adults. Enjoy flexible hours, comprehensive support, and opportunities for professional growth while making a...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$141K - $177K *

Lead clinical initiatives by mentoring staff and providing patient-centered care in an urgent care setting, ensuring compliance and fostering collaboration for optimal health outcomes...

3 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs can I find in Massachusetts?question toggle

    Listings may include professional and leadership roles across fields such as technology, healthcare, finance, biotechnology, education, manufacturing, and business services. Available positions change, so browse current listings for the latest opportunities.

  • Where can I find professional jobs in Massachusetts?question toggle

    Search across the state, including major employment centers such as Boston, Cambridge, and Worcester. You can also use location filters to explore roles in other Massachusetts communities.

  • Are the Massachusetts jobs on Ladders vetted?question toggle

    Ladders features vetted professional job listings paying $100,000 or more. Review each listing for details about the employer, responsibilities, qualifications, and compensation.

  • How can I find a Massachusetts job that matches my experience?question toggle

    Use filters such as location, job title, industry, and seniority to narrow your search. Keep your resume current and compare each listing’s requirements with your skills and career goals.