Find vetted professional opportunities in South Dakota with salaries of $100,000 or more on Ladders. From established employers in Sioux Falls and Rapid City to roles across the state, explore openings for experienced professionals seeking their next career move.
South Dakota’s economy includes healthcare, financial services, manufacturing, technology, agriculture, energy, and professional services. High-paying positions may include leadership, specialized technical, clinical, sales, and operations roles. Availability and compensation vary by employer, location, and experience.
Sioux Falls is a major center for healthcare, finance, and business services, while Rapid City offers opportunities in healthcare, tourism, government, and regional services. Employers in smaller cities and rural areas may also hire for specialized and senior-level positions.
Browse South Dakota listings, review salary and experience requirements, and focus your search on positions that match your expertise and career goals. New opportunities may be added as employers hire, so check back regularly.
$100K - $120K *
Elevate patient care by providing expert pharmacy consulting and clinical services. Collaborate with a dedicated team to ensure medication safety and mentor future pharmacists while enjoying growth op...
1 week ago
$100K - $120K *
Join a dynamic team to provide expert pharmacy consulting, educate patients on medications, and deliver clinical healthcare services while ensuring safety and compliance. Mentor colleagues and enhance...
1 week ago
$100K - $120K *
Join us to oversee pharmacy services, ensuring quality care through effective planning, execution, and evaluation. Collaborate with healthcare teams to enhance patient outcomes while supervising staff...
1 week ago
$108K - $135K *
Join our team as a Telehealth Pharmacist, where you'll enhance member health through Medication Therapy Management and clinical outreach programs, ensuring high-quality care and compliance with indust...
4 days ago
$84K - $99K *
Join a dynamic team to evaluate and process medication prior authorization requests, ensuring compliance with clinical guidelines and regulatory standards while facilitating timely patient access to n...
6 days ago
$101K - $126K *
Drive the development and execution of clinical programs, ensuring effective support, education, and coordination across departments while managing health outcomes and utilization data for continuous...
Reposted yesterday
$110K - $130K *
Take ownership of medication therapy management services, conducting comprehensive reviews and consultations. Collaborate with the MTM product team to ensure accurate data entry and enhance patient ca...
Yesterday
Clinical Pharmacist (Formulary & Quality)
$107K - $199K *
Redefine pharmacy care by developing formularies and policies, enhancing quality programs, and driving initiatives that improve Medicaid services while collaborating with diverse teams and stakeholder...
4 weeks ago
Managed Care Pharmacist - Managed Care/PBM
$110K - $130K *
Transform pharmacy outcomes by leading managed care initiatives that optimize clinical programs, enhance stakeholder collaboration, and drive cost efficiencies in pharmacy benefit management...
Reposted 2 weeks ago
$100K - $120K *
Drive excellence in pharmacy operations by providing exceptional patient care, ensuring compliance with regulations, and fostering strong relationships with healthcare providers while managing workflo...
3 weeks ago
$110K - $130K *
Empower decision-making by utilizing data-driven insights to enhance operations, supporting growth through statistical modeling and AI techniques while maintaining compliance in a complex regulatory e...
Reposted 1 week ago
$100K - $120K *
Join a team that's dedicated to delivering exceptional patient care while supervising pharmacy staff and championing operational excellence in a compliant environment. Contribute to cultural initiativ...
Yesterday
Pharmacist - Avera Family Health Center - Mitchell | Ambulatory Care
$100K - $120K *
Drive optimal patient care by collaborating with healthcare teams to enhance medication therapy and improve clinical outcomes for patients with chronic conditions. Ensure safe medication management an...
2 weeks ago
Director, Demand & Supply Planning
$125K - $150K *
Transform Drug Supply Chain Operations by leading cross-functional teams to establish reliable planning cadences and robust processes, ensuring continuous delivery of medication while driving efficien...
Reposted 4 weeks ago
$110K - $130K *
Drive medication therapy management services by conducting comprehensive reviews and consultations. Collaborate with the MTM product team to ensure accurate data entry and enhance patient care through...
1 week ago
Pharmacy District Manager, Amazon Pharmacy
$130K - $176K *
Inspire operational excellence as a strategic leader overseeing 8-10 pharmacies. Drive compliance, enhance patient care, and develop talent while ensuring consistent performance across multiple locati...
1 week ago
Pharmacist, Home Infusion - Evernorth - Hybrid or Remote
$112K - $189K *
Join us to ensure safe, effective medication therapy while advancing pharmaceutical care. Collaborate with healthcare teams, educate future practitioners, and support drug-related research to optimize...
Today
Pharmacist | Cancer Care Institute
$100K - $120K *
Empower patient health by using your clinical expertise to oversee medication management and collaborate with healthcare professionals, ensuring optimal therapeutic outcomes across care settings for d...
Reposted today
$100K - $120K *
Unlock potential by delivering expert pharmacy consulting and clinical services. Collaborate with a dedicated team to ensure medication safety, educate patients, and mentor pharmacy staff in a support...
3 weeks ago
$100K - $120K *
Inspire healthcare excellence by providing expert pharmacy consulting, educating patients on medication use, and ensuring safety through compliance. Collaborate with a dedicated team to deliver clinic...
3 weeks ago
$100K - $120K *
Drive patient-centered pharmacy services by providing expert consultations, educating on medication use, and ensuring safety through compliance. Mentor team members while delivering clinical healthcar...
3 weeks ago
Pharmacist Account Manager - Remote Nevada
$108K - $184K *
Unlock potential by leveraging clinical expertise to enhance pharmacy benefit management, analyze drug trends, and build strong client relationships. Drive strategic recommendations and support client...
1 week ago
Clinical Pharmacist - Value Based Care
$110K - $130K *
Unlock potential by leading a remote pharmacy program focused on medication adherence. Collaborate with a specialized team to enhance patient care through data-driven strategies and operational suppor...
6 days ago
$88K - $149K *
Join a dynamic team in evaluating medication prior authorizations while developing clinical criteria and working closely with healthcare providers to ensure quality patient care through evidence-based...
4 weeks ago
Medical Director -Pharmacy Appeals
$223K - $313K *
Shape the future of healthcare by leveraging your clinical expertise to review Medicare drug appeals, ensuring compliance and optimal value-based care through collaboration and analysis of complex cas...
6 days ago
What types of $100,000-plus jobs are available in South Dakota?
Depending on current openings, roles may span healthcare, finance, technology, manufacturing, sales, operations, and executive leadership. Requirements and salaries vary by position and employer.
Which South Dakota cities have professional job opportunities?
Sioux Falls and Rapid City are major employment centers, and opportunities may also be available in communities throughout the state.
How can I find high-paying jobs in South Dakota?
Use Ladders to browse vetted professional listings, compare role requirements, and identify openings with salaries of $100,000 or more.
Do South Dakota jobs listed on Ladders all pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Check each listing for its specific compensation details and requirements.