Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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$76K - $90K *

Optimize supply chain insights and capabilities, driving client value through data-driven storytelling and collaboration. Lead initiatives that enhance decision-making and foster partnerships, while m...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Enterprise Technology

$80K - $145K *

Join a team that's advancing data analytics for VA modernization initiatives. Utilize SQL and Python to drive AI-enabled insights, enhance operational workflows, and support decision-making through ri...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Business Services

$54K - $159K *

Drive your career with impactful leadership in Medicare supplemental benefits. Oversee implementation and operations, ensuring effective program delivery and continuous improvement in a dynamic, colla...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Empower your career by joining a dynamic team as an Epic Prelude Analyst, driving enhancements in patient access and revenue cycle workflows through collaboration and innovative solutions...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Engage in cutting-edge AI development by designing and scaling intelligent applications. Leverage Generative AI and modern tools to enhance productivity and integrate workflows within healthcare platf...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$170K - $190K *

Transform the future of enterprise deployment by leading SAP S/4HANA initiatives across multiple regions. Drive strategic alignment, ensure operational readiness, and deliver measurable outcomes while...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$125K - $143K *

Drive the development and execution of tailored training programs, ensuring effective skill enhancement for sales representatives. Collaborate with cross-functional teams to align training strategies...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in managing complex clinical trials, ensuring timely delivery, budget adherence, and high-quality outcomes while collaborating with multidisciplinary teams and stakeholders to enhance...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Contribute to quality operations initiatives by reviewing study documents, supporting audits, and ensuring compliance with regulatory standards. Collaborate with cross-functional teams to enhance qual...

RemoteRemote

5 days ago

  •   5 - 7 years exp.  •   Finance & Insurance

$205K - $380K *

Engage as a strategic leader in enterprise sales, driving growth by securing key healthcare partnerships and executing market strategies. Collaborate with cross-functional teams to enhance customer va...

United StatesRemote

4 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$78K - $119K *

Lead the charge in enhancing palliative care operations, ensuring high-quality support for patients with advanced chronic illnesses. Collaborate with diverse teams to improve care coordination and pat...

Pascagoula, MSRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$210K - $250K *

Unlock potential by leading strategic initiatives to expand faculty and enhance academic excellence. This role involves mentorship, vision, and collaboration to meet diverse educational and clinical n...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$156K - $212K *

Shape the future of training by leading impactful learning solutions for obesity and related conditions. Collaborate with cross-functional teams to design and deliver engaging curricula that enhance f...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$55K - $109K *

Engage in leading the dental Provider Relations team, enhancing provider relationships and operational effectiveness. Drive network management activities to ensure member access to care and improve pr...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $160K *

Contribute to the evolution of data-driven healthcare products, shaping strategy and execution. Collaborate with cross-functional teams to deliver AI-enabled solutions that enhance clinical outcomes a...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $180K *

Unlock the potential of brand innovation by leading strategy and consumer insights for new product launches. Collaborate across teams to shape compelling narratives and ensure market readiness, drivin...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$150K - $180K *

Innovate the future of architectural strategy by leading technical direction, fostering collaboration across teams, and driving scalable solutions that align with business goals while mentoring senior...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Healthcare

$145K - $218K *

Architect innovative market access strategies to enhance U.S. reimbursement for cutting-edge healthcare solutions. Collaborate across functions to drive payer engagement, coding, and coverage initiati...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$95K - $115K *

Join a dynamic team to support product management for government insurance, ensuring compliance and driving strategic initiatives. Leverage your expertise to lead analysis, define requirements, and en...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $190K *

Drive member activation by leading a cross-functional team to optimize outreach, incentives, and messaging strategies. Own the activation roadmap and funnel metrics to enhance engagement and ensure sc...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$94K - $136K *

Transform financial insights into strategic decisions by providing advanced analytical support across Finance, Operations, and Strategic Planning. Collaborate with leadership to drive impactful projec...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Optimize clinical support for Heart Alert Service by reviewing ECG episodes, ensuring accurate documentation, and collaborating across functions to enhance patient care and workflow efficiency...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$90K - $140K *

Transform your career by driving growth and adoption of innovative surgical glaucoma technology. Engage with healthcare professionals, deliver expert support, and build lasting relationships to enhanc...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Transform financial operations by leveraging Workday expertise to enhance reporting, payroll, and planning processes. Collaborate with cross-functional teams to deliver scalable solutions and drive co...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Optimize deal structuring and commercial solutions, partnering with sales to drive strategic opportunities. Manage proposals, objection handling, and internal approvals while enhancing collaboration a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.