Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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$73K - $115K *

Grow your career with a dynamic team focused on optimizing provider operations. Lead credentialing initiatives, implement AI solutions, and enhance workflows while ensuring compliance and operational...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Unlock your potential by analyzing Medicaid data to enhance program performance, quality, and access. Collaborate with diverse teams to develop insights that drive impactful decisions in healthcare an...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$225K - $265K *

Shape the future of oncology by leading clinical studies in early-phase development. Collaborate with multidisciplinary teams to drive innovative therapies and ensure high-quality execution of clinica...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$150K - $240K *

Advance healthcare delivery by leading a dynamic Care Coordination team, ensuring compliance with regulations, optimizing resource utilization, and enhancing patient care through strategic planning an...

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$186K - $233K *

Pioneer innovative strategies in breast oncology, driving commercial success through collaboration and data-driven insights. Lead cross-functional teams to enhance product adoption and optimize market...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$115K - $125K *

Drive the development and management of virtual health services, enhancing operational excellence and patient experience while scaling innovative care models across the organization. Lead strategic in...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$80K - $100K *

Shape the future of medical communications by crafting high-quality, scientifically accurate content. Collaborate with diverse teams to deliver impactful resources that meet client needs while mentori...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$171K - $246K *

Shape the future of mental health care by providing remote psychiatric assessments and treatments. Deliver compassionate support to diverse clients, focusing on adults and adolescents, while collabora...

RemoteRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Healthcare

$101K - $126K *

Join a dynamic team to lead complex projects, ensuring timely delivery and alignment with strategic goals. Collaborate across departments, manage risks, and mentor others while leveraging best practic...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$291K - $307K *

Innovate as you lead the Logistics product organization, shaping strategy and vision for sustainable growth while driving efficiencies that enhance the marketplace experience for customers, shoppers...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Consumer Technology

$110K - $130K *

Unlock your potential by managing key accounts in the pet food industry. Collaborate with diverse brands to drive growth, enhance customer relationships, and execute strategic plans that improve pet h...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$177K - $221K *

Champion global revenue accounting policies and lead technical assessments across U.S. and international markets, ensuring compliance with U.S. GAAP and SEC reporting while collaborating with regional...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Empower business success by collaborating with cross-functional teams to enhance operations, gather requirements, and implement IT solutions that align with strategic goals. Drive improvements in orde...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Transform your career with a pivotal role in clinical research, leading oncology studies and collaborating with cross-functional teams to ensure scientific excellence and regulatory compliance while m...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Innovate clinical system implementations by ensuring seamless integration of technologies and workflows. Collaborate with clinical and technical teams to enhance patient care and operational efficienc...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$156K - $214K *

Transform the digital landscape for Medical Affairs by owning product vision, prioritizing backlogs, and ensuring compliance. Collaborate with experts to deliver insights and enhance engagement throug...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$404K - $500K+*

Transform the Federal Civilian landscape by leading sales teams to drive adoption of cybersecurity and data solutions. Cultivate executive relationships, establish GTM strategies, and achieve multi-mi...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Telecommunications & Hardware

$110K - $130K *

Lead the charge in Epic solutions delivery by providing expert support, managing projects, and mentoring team members. Shape the future of healthcare IT by aligning technical teams with stakeholder ne...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Empower your career by leading sales strategies across the US. Collaborate with a dynamic team to drive growth, develop client relationships, and deliver impactful presentations while navigating indus...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $140K *

Shape the future of healthcare integration by leading and executing complex HL7 projects. Utilize your expertise in medical informatics and enhancing customer satisfaction while managing dynamic, mult...

United StatesRemote

Reposted 2 days ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$95K - $110K *

Partner with us to transform healthcare delivery by providing telephonic clinical triage and support. You'll advocate for members, ensuring they receive timely care while collaborating with a dedicate...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Advance global service delivery by managing offshore partnerships, ensuring performance excellence, and driving operational improvements across teams to enhance productivity and quality outcomes...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Healthcare

$101K - $154K *

Shape product strategy and commercialization efforts, ensuring alignment with market trends and customer needs. Drive product development, marketing initiatives, and cross-functional collaboration to...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$90K - $105K *

Advance your career by leading a dedicated team in delivering trauma-informed care for substance use disorders. Shape clinical practices and foster a supportive environment in a new clinic focused on...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Champion the growth of hematology products by educating healthcare providers, driving demand, and fostering relationships within cancer centers. Leverage cross-functional teams to ensure a positive ex...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.