Explore $100K+ Jobs in Mississippi

Discover professional opportunities in Mississippi with Ladders, where job seekers can explore vetted roles paying $100,000 or more. From positions in Jackson and the Gulf Coast to opportunities in communities across the state, find roles that match your experience, skills, and career goals.

Professional Opportunities Across Mississippi

Mississippi employers hire experienced professionals across industries such as healthcare, finance, manufacturing, technology, energy, and business operations. Available roles and compensation vary by employer, location, and qualifications, so review each listing for details about responsibilities, salary, and requirements.

Search in Mississippi Cities and Regions

Find opportunities in major employment centers including Jackson, Gulfport, and Southaven, as well as other Mississippi communities. Use location and job-title filters to focus your search, and consider remote or hybrid listings when available.

Find a Role That Fits Your Career

Compare opportunities by seniority, specialty, and work arrangement. Keep your résumé current, highlight measurable results, and tailor your application to the qualifications in each listing. Ladders helps professionals explore vetted jobs with salaries of at least $100,000.

Start Your Mississippi Job Search

Browse Mississippi jobs on Ladders and take the next step toward a professional opportunity aligned with your expertise and compensation goals. Listings change frequently, so check back for new roles.

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$155K - $160K *

Shape the future of data solutions by designing scalable architectures that drive AI and analytics initiatives. Collaborate with cross-functional teams to implement innovative strategies that enhance...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$165K - $206K *

Contribute to innovative research by leveraging advanced mass spectrometry to uncover biological insights and drive drug discovery. Collaborate across disciplines to develop impactful therapeutic moda...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$177K - $195K *

Engage with healthcare professionals to build relationships and provide education on HAE treatment. Drive access support and promote Donidalorsen while collaborating with cross-functional teams to enh...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$147K - $192K *

Tackle new opportunities in the healthcare sector by driving sales and strategy. Engage with C-suite executives, implement effective sales policies, and analyze market trends to maximize revenue growt...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Healthcare

$100K - $130K *

Lead the charge in enhancing member care as you coach and develop clinical teams, oversee daily operations, and ensure compliance with regulatory standards while driving quality improvements and opera...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Unlock potential by leading product marketing strategies for developer-facing solutions. Collaborate across teams to enhance messaging, drive customer engagement, and ensure successful deployments, al...

United StatesRemote

2 days ago

  •   5 - 7 years exp.  •   Information Technology

$193K - $244K *

Support business growth by drafting and negotiating partner agreements, providing strategic legal advice, and leading cross-functional projects. Collaborate with internal teams to ensure compliance an...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Consumer Technology

$120K - $145K *

Join a team that's advancing oncology solutions by managing global clinical trials. Lead project execution from protocol development to study closeout, ensuring quality and compliance while fostering...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join a team that's dedicated to enhancing community care for Veterans. Oversee nursing practices, coordinate patient referrals, and collaborate with multidisciplinary teams to ensure high-quality care...

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$100K - $162K *

Drive sales growth in assigned territory by developing strategic plans, conducting impactful presentations, and fostering strong relationships with healthcare professionals while adhering to ethical p...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Accelerate progress at an innovative healthcare firm by leading account-based marketing initiatives. Collaborate closely with Sales to create impactful marketing plays that engage targeted health syst...

United StatesRemote

1 month ago

  •   5 - 7 years exp.  •   Healthcare

$272K - $340K *

Join a team that's driving CMC strategy and execution for innovative therapies. Lead cross-functional efforts in drug and device development, ensuring compliance and operational excellence from clinic...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$136K - $170K *

Shape the future of quality assurance by managing chemistry and microbiology labs, ensuring compliance with regulations, and driving continuous improvement in product quality and safety through effect...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$100K - $120K *

Elevate patient care by delivering virtual health services, ensuring compliance with regulations, and fostering teamwork in a dynamic environment. Utilize your expertise to provide accurate diagnoses...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $135K *

Transform compliance oversight in the DME order-to-payment lifecycle. Lead audits, analyze data, and coordinate payer audits while developing practical controls and reporting to enhance revenue integr...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $145K *

Lead campaign strategy and execution for oncology pharma marketing, driving performance optimization and cross-functional collaboration. Own end-to-end campaign management, ensuring alignment with bus...

United StatesRemote

Reposted 3 days ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Empower our rehabilitation team by leading operations, ensuring compliance, and enhancing patient care. Drive financial success and foster strong relationships with staff and clients while maintaining...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$175K *

Optimize revenue cycle management by leading a dynamic team to enhance processes, drive automation, and ensure compliance in a fast-paced telehealth environment. Collaborate with cross-functional team...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$200K - $398K *

Drive impactful legal strategies in a global clinical research environment, guiding senior leadership on complex regulatory and compliance matters while fostering innovation and risk management across...

RemoteRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$90K - $110K *

Lead the charge in delivering comprehensive patient care as a Nurse Practitioner, collaborating with healthcare teams to ensure effective diagnosis, treatment, and education while maintaining high sta...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Join a dynamic healthcare team to provide comprehensive patient care, ensuring effective diagnosis, treatment, and education. Collaborate with multidisciplinary teams to enhance patient outcomes while...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$90K - $110K *

Advance patient care by examining and treating individuals independently while collaborating with healthcare teams. Utilize your expertise to ensure effective diagnosis, treatment, and education, all...

3 days ago

  •   Less than 5 years exp.  •   Healthcare

$180K - $215K *

Drive regional sales success by leading a high-performing team, executing launch strategies, and fostering customer relationships to achieve business objectives in a dynamic environment...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Join a team that's dedicated to optimizing revenue cycle operations, ensuring compliance, and enhancing service quality. Lead daily activities, mentor staff, and collaborate with senior leadership to...

Reposted 2 days ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$82K - $182K *

Develop and maintain QuickBase applications while leading complex analytics projects. Ensure data integrity and support clinical performance reporting. Collaborate with stakeholders to drive continuou...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of jobs can I find in Mississippi on Ladders?question toggle

    You can explore professional opportunities across fields such as healthcare, finance, manufacturing, technology, energy, and business operations. Roles and availability vary over time.

  • Are Mississippi jobs on Ladders vetted?question toggle

    Ladders hosts vetted professional jobs that pay $100,000 or more. Check each listing for compensation details, qualifications, and other job-specific information.

  • Where in Mississippi can I search for jobs?question toggle

    Search across the state, including employment centers such as Jackson, Gulfport, and Southaven. You can use location filters to narrow results.

  • How can I find remote or hybrid jobs based in Mississippi?question toggle

    Use available work-arrangement filters or review listing details to identify remote and hybrid opportunities. Availability depends on the employer and role.

  • How do I improve my chances of getting hired for a Mississippi job?question toggle

    Tailor your résumé to the role, emphasize relevant experience and measurable outcomes, and ensure you meet the listed qualifications before applying.