Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$136K - $230K *

Elevate customer success by delivering Professional Services engagements, including installation, migration, and training, while collaborating with project managers to enhance delivery consistency and...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Information Technology

$95K - $115K *

Elevate the development of innovative chemical processes by optimizing existing routes and synthesizing key intermediates. Collaborate with teams to ensure project success while maintaining safety and...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$164K - $305K *

Join a team that's redefining account management by driving growth and retention for complex health systems. Build strategic relationships with C-suite executives and lead cross-functional teams to de...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$163K - $203K *

Lead the charge in executing compliance strategies across regulated sectors, ensuring robust oversight and operational clarity while collaborating with cross-functional teams to navigate regulatory la...

RemoteRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$82K - $112K *

Shape compelling product narratives by leveraging market insights and AI tools. Collaborate cross-functionally to drive go-to-market strategies, ensuring impactful messaging and training materials tha...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$115K - $192K *

Drive success by managing strategic merchant partnerships, blending account management and operations to enhance performance and growth. Collaborate cross-functionally to deliver scalable solutions an...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Transportation

$173K - $310K *

Transform clinical AI solutions by leveraging your expertise in patient care and research. Collaborate cross-functionally to enhance clinical accuracy and support strategic partnerships, ensuring the...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$220K - $240K *

Lead the charge in delivering exceptional customer experiences throughout the customer journey. Collaborate with cross-functional teams to drive growth, strategy, and insight within a global, high-imp...

1 month ago

  •   8 - 10 years exp.  •   Business Services

$220K - $240K *

Elevate customer success across the full lifecycle by developing strategies, leading multi-disciplinary teams, and ensuring industry-leading support, insights, and partnership within a global commerci...

1 month ago

  •   8 - 10 years exp.  •   Business Services

$220K - $240K *

Transform customer experiences by leading a global Customer Success organization, driving engagement, insights, and strategy across commercial, product, and analytics teams to deliver long-term value...

1 month ago

  •   8 - 10 years exp.  •   Business Services

$220K - $240K *

Optimize customer success through strategic leadership and analytics, guiding a global team to deliver exceptional customer experiences and drive market growth in the Resins & Technologies sector...

RemoteRemote

1 month ago

  •   8 - 10 years exp.  •   Business Services

$120K - $145K *

Lead the charge in defining and activating brand strategies across multiple channels, enhancing donor engagement and retention through innovative content and social communications while collaborating...

RemoteRemote

5 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$175K - $250K *

Lead the charge in executing clinical outsourcing strategies across oncology trials, managing vendor relationships, contract negotiations, and financial oversight to ensure optimal performance and com...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Empower medical initiatives by leading project teams, providing strategic guidance, and ensuring compliance with regulatory standards while fostering high-performing teams in a dynamic environment...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$89K - $155K *

Advance patient care by connecting with medical professionals, delivering clinical insights, and driving product utilization through strategic sales initiatives and relationship management in a dynami...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Manage the operational backbone of multiple HCI portfolios by coordinating and executing initiatives, engaging with diverse stakeholders, and overseeing project timelines, budgets, and deliverables fo...

RemoteRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$180K - $190K *

Join a team that's dedicated to advancing precision medicine by leveraging AI to provide cutting-edge educational support and scientific expertise on cancer biomarker tests while engaging key opinion...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Healthcare

$87K - $136K *

Elevate our Sales and Operations Planning by leading demand and supply strategies, ensuring product availability while managing inventory and cash flow. Collaborate with cross-functional teams to driv...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$134K - $223K *

Lead digital web projects, ensuring optimal performance and compliance across the GSK.com platform. Collaborate with cross-functional teams to enhance user experience, mitigate cybersecurity risks, an...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Elevate project outcomes by leading cross-functional teams to deliver clinical research projects on time and within budget, ensuring compliance with regulatory standards and client expectations while...

United StatesRemote

Reposted 2 days ago

  •   Less than 5 years exp.  •   Healthcare

$170K - $200K *

Transform the future of AI governance by leading enterprise strategy, ensuring compliance, and managing risks across the AI lifecycle. Collaborate with cross-functional teams to implement responsible...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$180K - $220K *

Drive the enterprise data strategy and governance, ensuring data quality, compliance, and accessibility. Lead cross-functional teams to foster a data-rich culture, enabling advanced analytics and AI r...

United StatesRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Healthcare

$100K - $120K *

Unlock potential by leading community programs, overseeing loan and grant administration, and fostering relationships with stakeholders to enhance rural development initiatives and ensure effective pr...

1 week ago

  •   Less than 5 years exp.  •   Transportation

$82K - $115K *

Innovate faculty management and student engagement strategies while coaching and supporting educators. Drive academic excellence and uphold performance standards within a dynamic educational environme...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Drive revenue growth by cultivating relationships and managing the full-cycle sales process in the healthcare technology sector. Utilize AI-driven solutions to enhance client performance and deliver v...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.