Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$150K - $180K *

Innovate the future of architectural strategy by leading technical direction, fostering collaboration across teams, and driving scalable solutions that align with business goals while mentoring senior...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Healthcare

$60K - $129K *

Transform lives by providing expert case management and crisis intervention for members facing behavioral health challenges. Leverage your clinical skills to develop care plans, coordinate services, a...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$145K - $218K *

Architect innovative market access strategies to enhance U.S. reimbursement for cutting-edge healthcare solutions. Collaborate across functions to drive payer engagement, coding, and coverage initiati...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$172K - $233K *

Join a dynamic team as a Senior Medical Science Liaison, driving scientific engagement with healthcare providers to enhance patient outcomes in obesity and related conditions. Collaborate with key opi...

2 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$95K - $115K *

Join a dynamic team to support product management for government insurance, ensuring compliance and driving strategic initiatives. Leverage your expertise to lead analysis, define requirements, and en...

RemoteRemote

4 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$150K - $190K *

Drive member activation by leading a cross-functional team to optimize outreach, incentives, and messaging strategies. Own the activation roadmap and funnel metrics to enhance engagement and ensure sc...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$94K - $136K *

Transform financial insights into strategic decisions by providing advanced analytical support across Finance, Operations, and Strategic Planning. Collaborate with leadership to drive impactful projec...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $145K *

Optimize clinical support for Heart Alert Service by reviewing ECG episodes, ensuring accurate documentation, and collaborating across functions to enhance patient care and workflow efficiency...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$90K - $140K *

Transform your career by driving growth and adoption of innovative surgical glaucoma technology. Engage with healthcare professionals, deliver expert support, and build lasting relationships to enhanc...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Transform financial operations by leveraging Workday expertise to enhance reporting, payroll, and planning processes. Collaborate with cross-functional teams to deliver scalable solutions and drive co...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Optimize deal structuring and commercial solutions, partnering with sales to drive strategic opportunities. Manage proposals, objection handling, and internal approvals while enhancing collaboration a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$120K - $130K *

Unlock potential by leading complex data engineering initiatives, enhancing platform reliability, and mentoring junior engineers. Collaborate across teams to design and implement scalable solutions wh...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $115K *

Analyze and enhance client data reporting, driving insights and trends to support customer satisfaction and business growth. Collaborate with cross-functional teams to ensure data integrity and delive...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$135K - $170K *

Champion our SOX compliance efforts by managing key activities, collaborating with teams, and enhancing internal controls. Bring your expertise in public accounting and life sciences to drive improvem...

3 days ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$126K - $189K *

Join a team that's leading provider enrollment operations, ensuring timely onboarding, compliance, and accuracy. Drive strategic initiatives and enhance operational efficiency across networks while co...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Healthcare

$120K - $250K *

Transform clinical trials by ensuring patient safety and scientific integrity. Collaborate with stakeholders to uphold regulatory standards and optimize study protocols, while providing expert medical...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$175K - $200K *

Lead the charge in developing integrated media strategies and client partnerships across pharmaceutical and life sciences accounts, driving business growth and ensuring exceptional delivery and client...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Advance financial operations by managing project finance teams, enhancing reporting processes, and supporting month-end close activities. Collaborate with stakeholders to ensure accurate revenue recog...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$135K - $160K *

Advance your career by managing financial operations for project teams, enhancing reporting accuracy, and leading financial analysis to support clinical trials and strategic decision-making...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Healthcare

$90K - $117K *

Elevate your career by leading SDTM programming activities, ensuring quality deliverables, and collaborating cross-functionally to optimize clinical data transformation in a dynamic environment...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Empower your veterinary career by providing urgent care for pets in a supportive, modern environment. Collaborate with a dedicated team to manage diverse cases while enjoying a flexible schedule and o...

4 weeks ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$69K - $125K *

Transform regulatory insights into actionable strategies by analyzing national and state legislative activities. Collaborate with legal and business teams to ensure compliance and support effective de...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$190K - $235K *

Transform the future of digital marketing strategy by leading cross-functional initiatives that align brand objectives with innovative digital capabilities, ensuring a cohesive and effective customer...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Shape the future of brand strategy by leading integrated initiatives, translating insights into actionable plans, and collaborating with cross-functional teams to deliver impactful solutions across as...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$160K - $200K *

Join a dynamic team as a senior leader driving profitable growth in healthcare services. Oversee sales strategy, lead a high-performing team, and collaborate across functions to deliver innovative sol...

RemoteRemote

Reposted yesterday

  •   5 - 7 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.