Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$80K - $95K *

Join our team to drive sales across a defined portfolio, engaging healthcare organizations with our innovative solutions. Own the sales cycle from prospecting to closing while collaborating with inter...

United StatesRemote

Reposted 4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$138K - $188K *

Lead global trade compliance initiatives, ensuring adherence to regulations across multiple jurisdictions. Drive strategic programs for import/export operations, risk management, and partner governanc...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$175K - $210K *

Shape the future of corporate law by providing strategic legal counsel on M&A, governance, and compliance for a dynamic multinational company. Collaborate with diverse teams to navigate complex transa...

United StatesRemote

2 days ago

  •   11 - 15 years exp.  •   Manufacturing & Automotive

$158K - $197K *

Unlock potential by leading the automation of clinical data integration and dashboard development. Collaborate across teams to enhance data usability and implement AI solutions, ensuring compliance an...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $215K *

Lead regional sales initiatives, driving product launch success and team performance. Collaborate cross-functionally to execute strategies, foster customer relationships, and ensure compliance while b...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$157K - $213K *

Lead the charge in shaping innovative training for Oncology Sales teams, collaborating with cross-functional leaders to enhance curricula and drive business success in a dynamic environment focused on...

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $181K *

Shape the future of nursing education by leading curriculum development, faculty empowerment, and student success initiatives. Drive compliance and foster collaboration to enhance academic operations...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$195K - $264K *

Champion growth by leading a team of Pulmonology Medical Specialists, driving sales performance, and fostering talent development while ensuring compliance and integrity in a dynamic market environmen...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Analyze performance metrics to empower ACOs in Value-Based Care programs. Collaborate with teams to provide actionable insights, track KPIs, and optimize risk scores, driving data-driven decisions for...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$194K - $361K *

Lead the development of innovative NovaOS capabilities, ensuring alignment with business goals and driving continuous improvement through collaboration across cross-functional teams. Deliver measurabl...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Elevate your career by leading multiple dialysis centers, driving operational excellence, and fostering a culture of patient care. Collaborate with a dedicated team to achieve strategic growth and ens...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $322K *

Join a team that's dedicated to delivering compassionate psychiatric care to incarcerated individuals with complex needs. Collaborate with a multidisciplinary team to support recovery and improve ment...

1 month ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$116K - $145K *

Optimize proposal performance and strategic growth initiatives, leading a collaborative team to enhance RFP responses, competitive positioning, and resource allocation for maximum impact and success a...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$156K - $247K *

Transform patient support strategies and services to ensure effective access for patients navigating their treatment journey, fostering innovative solutions and improving overall patient experiences t...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$200K - $250K *

Accelerate progress at our rapidly growing segment by leading sales efforts into child welfare and behavioral health markets. Build relationships, drive pipeline development, and execute sales strateg...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$140K - $185K *

Accelerate progress at the forefront of payor relations, leading a team to develop strategic partnerships that enhance patient access and optimize reimbursement for innovative medical technologies in...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Unlock potential by leading Health and VA claims operations, driving strategic initiatives, enhancing recovery outcomes, and ensuring operational excellence across multiple teams and client portfolios...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$134K - $162K *

Contribute to the advancement of medical physics by leading dosimetry analysis for radiopharmaceuticals. Collaborate with cross-functional teams to drive research in drug development and improve imagi...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$178K - $238K *

Drive impactful oncology drug development by leading program management, optimizing team efficiency, and ensuring strategic alignment across global projects to enhance patient outcomes and organizatio...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$120K - $150K *

Drive reputation management and consumer insights initiatives, enhancing brand trust and informing strategic decisions. Collaborate across teams to analyze data, identify trends, and improve consumer...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$89K - $171K *

Transform your career by connecting with healthcare professionals and driving product utilization. In this dynamic role, you'll lead sales efforts, build relationships, and contribute to patient care...

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive customer success by managing key accounts, ensuring satisfaction, and expanding revenue through upselling. Collaborate with internal teams to align customer needs with solutions, while leveragin...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$104K - $141K *

Lead the charge in transforming Human Genetics strategy into actionable plans, ensuring measurable progress across R&D. Collaborate with cross-functional teams to align priorities and drive successful...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$100K - $150K *

Join a team that's dedicated to enhancing clinical support through technical expertise and customer training. Drive product demonstrations and ensure customer satisfaction while collaborating with sal...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Champion strategic marketing initiatives to drive growth in North America. Collaborate with cross-functional teams to develop market strategies, analyze trends, and enhance customer engagement, ensuri...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.