Explore $100K+ Jobs in Iowa

Discover professional opportunities across Iowa with Ladders. Browse vetted job listings with salaries of $100,000 or more, from leadership and technology roles to finance, healthcare, engineering, and other specialized careers. Whether you’re considering a move or looking to advance your career close to home, explore opportunities in Iowa’s major employment centers and beyond.

Where to Find Professional Jobs in Iowa

Iowa offers career opportunities in cities and communities throughout the state. Des Moines is a major center for insurance, financial services, healthcare, and corporate leadership. Cedar Rapids and Iowa City have opportunities in technology, advanced manufacturing, education, and healthcare, while other regional hubs support a range of professional and industrial employers. Job availability and compensation vary by role, employer, and location.

In-Demand Fields and Roles

High-paying Iowa jobs can be found across industries such as insurance and finance, healthcare, information technology, engineering, manufacturing, agriculture-related business, and executive management. Employers may seek experienced professionals in areas including software and data, operations, sales, accounting, clinical leadership, and product or project management. Review each posting for its specific qualifications, responsibilities, and compensation details.

Find the Right Iowa Opportunity

Use Ladders to explore vetted professional openings with listed salaries of $100,000 or more. Refine your search by job title, industry, location, and other preferences. Compare roles and employer requirements, then apply to opportunities that align with your experience and career goals. Listings and salary information can change, so check individual postings for the latest details.

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$210K *

Empower patients through innovative telehealth solutions. Join our team of board-certified OB/GYN physicians to deliver high-quality, patient-centered care across Iowa, balancing flexibility with clin...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$210K *

Engage in a rewarding telehealth role, providing compassionate care across various clinical cases. Enjoy flexible scheduling while delivering high-quality virtual consultations to patients throughout...

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$141K - $196K *

Unlock potential by developing causal machine-learning models to optimize customer offers, analyzing complex data, and translating findings into actionable strategies for enhanced conversion rates acr...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Finance & Insurance

$235K - $270K *

Join a team that's driving access strategy across the Northeast, managing key payer relationships and ensuring launch readiness for rare disease therapies. Collaborate with cross-functional teams to o...

United StatesRemote

3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Shape the future of patient access by leading integrated strategies that enhance customer engagement and optimize portfolio performance across diverse healthcare channels, driving sustainable growth a...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$166K - $244K *

Join a dynamic team to lead the Employer PMO, driving strategic program delivery and cross-functional alignment while enhancing operational efficiency and leveraging modern tools for impactful outcome...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$151K - $314K *

Shape the future of global ERP delivery by leading a diverse team, executing strategic initiatives, and driving transformation across multiple regions to enhance operational efficiency and business va...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$180K - $215K *

Transform your career by leading regional sales efforts, driving product launch success, and building high-performing teams. Collaborate cross-functionally to achieve sales goals and foster strong cus...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$203K - $245K *

Unlock potential by leading a national team of Thought Leader Liaisons to enhance KOL engagement and advocacy in oncology. Drive strategic initiatives, foster collaboration, and ensure compliance whil...

RemoteRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$200K *

Transform the landscape of life sciences partnerships by driving co-developed deals. Leverage your extensive network and expertise to source, pitch, and close high-value agreements that enhance patien...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Healthcare

$173K - $217K *

Unlock potential by driving high-quality statistical analyses and AI integration in the pharmaceutical sector. Collaborate across functions to enhance drug development and regulatory processes through...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Innovate healthcare delivery by serving as a clinical liaison, translating partner needs into actionable insights for chronic care and telehealth programs, impacting thousands of patients nationwide t...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$124K - $169K *

Drive strategic insights and analytics to enhance payer access and pricing strategies for biopharmaceutical products, ensuring optimal patient access in a complex healthcare landscape. Collaborate acr...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$122K *

Elevate your career by managing global projects in Neuroscience, ensuring compliance, budget adherence, and successful collaboration across cross-functional teams to drive milestone achievement and en...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Grow your career with a dynamic role that drives actionable insights across e-commerce and service delivery. Collaborate with stakeholders to analyze data, build impactful reports, and enhance busines...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Lead the charge in managing complex projects within the pharmaceutical and biotech sectors, ensuring successful execution and delivery while mentoring teams and collaborating with stakeholders to achi...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$124K - $169K *

Optimize cross-portfolio analytics to enhance Gross-to-Net performance, identify anomalies, and drive process improvements. Collaborate with diverse teams to deliver actionable insights and scalable r...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$190K - $205K *

Advance your career by driving growth in healthcare through impactful sales presentations and relationship management with hospital stakeholders. Collaborate across teams to optimize customer engageme...

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$124K - $135K *

Shape impactful training programs for Field Access teams, enhancing access and reimbursement capabilities across therapeutic areas. Collaborate with stakeholders to ensure compliance and relevance, fo...

United StatesRemote

2 days ago

  •   Less than 5 years exp.  •   Healthcare

$190K - $230K *

Join a team that's driving innovation in biopharma partnerships. Leverage your expertise to identify and advance strategic opportunities, influence cross-functional decisions, and manage alliances tha...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Business Services

$150K - $230K *

Drive the promotion of oncology products by building relationships with key stakeholders, exceeding performance goals, and ensuring patient access to therapies while managing territory resources effec...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$145K - $195K *

Engage with patients and healthcare providers to streamline access to therapy. Collaborate with internal teams and specialty pharmacies to resolve reimbursement issues and enhance patient support. Dri...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Drive a unified technical organization to enhance customer support from application discovery to project conversion, focusing on team development, technical selling, and improving customer experiences...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$135K - $160K *

Lead the charge in building a unified technical organization that enhances customer experience through application support and field service, driving project conversions and fostering a culture of con...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$114K - $210K *

Champion the development of regulatory documents for global submissions, managing timelines and cross-functional collaboration to ensure quality and compliance with industry standards while mentoring...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100,000+ jobs are available in Iowa?question toggle

    Openings may include leadership, technology, finance and insurance, healthcare, engineering, sales, and operations roles. Availability depends on employer needs, experience, and location; review current listings for specific opportunities.

  • Which Iowa cities have professional jobs paying $100,000 or more?question toggle

    Des Moines, Cedar Rapids, and Iowa City are among the state’s major employment centers, with professional opportunities also available in other Iowa communities. Search by location to see current openings.

  • How can I find high-paying jobs in Iowa on Ladders?question toggle

    Browse Iowa listings and use filters such as job title, industry, and location. Ladders features vetted professional jobs with salaries of $100,000 or more; check each posting for qualifications and compensation details.

  • Do Iowa job listings on Ladders include salary information?question toggle

    Ladders focuses on jobs with salaries of $100,000 or more. Individual postings provide the available compensation information, which may vary by role and employer.