Explore $100K+ Jobs in Alabama

Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.

Where to Find Professional Jobs in Alabama

Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.

Industries and Roles

High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.

Find the Right Alabama Opportunity

Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.

Advance Your Career in Alabama

Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.

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$150K - $180K *

Transform your career by driving new revenue growth in diverse industries. As a key sales leader, you'll identify prospects, develop relationships, and deliver tailored marketing solutions, ensuring c...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Media

$106K - $172K *

Elevate veterinary care by interpreting digital cytology and hematology cases. Collaborate with veterinarians, ensure quality control, and contribute to outreach efforts while maintaining high standar...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Unlock financial potential by analyzing complex healthcare contracts and data. Collaborate with health systems to translate insights into measurable outcomes, driving operational value and shaping AI...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$211K - $290K *

Champion global regulatory strategies to drive product approvals and market access for innovative dental solutions. Collaborate with cross-functional teams to navigate complex regulatory landscapes an...

RemoteRemote

3 days ago

  •   8 - 10 years exp.  •   Healthcare

$125K - $156K *

Drive data excellence by leading analytics initiatives, enhancing governance, and integrating systems. Collaborate with leadership to deliver impactful insights and ensure compliance while leveraging...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Staffing

$99K - $148K *

Unlock potential by delivering advanced nursing and medical services to Mental Health/Addiction clients, ensuring compliance with established protocols while providing comprehensive evaluations and co...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$235K - $270K *

Transform the landscape of oncology sales by driving growth within your territory. Collaborate with sales teams to identify opportunities, engage with key accounts, and promote cutting-edge diagnostic...

United StatesRemote

Reposted 3 days ago

  •   5 - 7 years exp.  •   Healthcare

$137K - $185K *

Elevate procurement strategies by analyzing supplier performance and collaborating cross-functionally to ensure material availability and operational efficiency, driving continuous improvement in supp...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$98K - $155K *

Accelerate progress at the forefront of value-based care by leading strategic partnerships, driving growth innovation, and optimizing performance across national health plans and ACOs while mentoring...

6 days ago

  •   8 - 10 years exp.  •   Healthcare

$150K - $180K *

Engineer advanced protein design models and collaborate with experts to innovate in AI Drug Discovery, driving the development of candidate antibody therapeutics through deep learning and systems biol...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$132K - $221K *

Drive enterprise-wide legal support for global contracting activities, focusing on procurement and technology transactions. Collaborate with cross-functional teams to manage risks and ensure complianc...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$72K - $97K *

Accelerate progress at clinical trials by supporting regional study delivery, ensuring quality standards, and collaborating with key stakeholders to meet study goals within timelines and budget...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$135K - $160K *

Drive strategic initiatives by developing KPI frameworks and operational dashboards, analyzing performance data, and collaborating across teams to enhance business outcomes and support informed decisi...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

$200K - $250K *

Champion the evolution of fraud prevention strategies, enhancing customer experience while safeguarding against risks. Collaborate cross-functionally to design innovative solutions that balance securi...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$210K - $250K *

Drive strategic financial planning and analysis to optimize resource allocation, support executive decision-making, and enhance operational performance across the organization, ensuring alignment with...

RemoteRemote

2 weeks ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$173K - $320K *

Shape the future of rheumatology by providing strategic medical oversight across clinical trials. Lead the innovation and development of groundbreaking therapies while collaborating with multidiscipli...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$176K - $230K *

Lead the charge in transforming healthcare through data-driven solutions. As a Senior Data Scientist, you'll spearhead projects that enhance patient outcomes, leveraging your expertise to align data s...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$126K - $173K *

Join a team that's redefining product management by owning the end-to-end strategy for Next Best Action. Collaborate with cross-functional teams to drive discovery, prioritize initiatives, and deliver...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$105K - $115K *

Join a team that's focused on diversifying paid media channels and optimizing conversion strategies. You'll lead initiatives across affiliate, programmatic, and social platforms to enhance member acqu...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Drive impactful clinical consulting by bridging expertise in real-world data with strategic insights. Collaborate across teams to enhance health outcomes research and contribute to thought leadership...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$134K - $179K *

Lead the charge in bridging genomic variants with clinical insights, collaborating with scientists to automate and scale curation workflows. Drive innovation in AI/ML applications while ensuring softw...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$145K - $165K *

Drive impactful clinical research strategies by collaborating with cross-functional teams, analyzing data, and disseminating findings through publications and presentations. Elevate your career while...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$101K - $203K *

Transform product strategy by leading digital product development and enhancements. Collaborate with cross-functional teams to gather insights, prioritize initiatives, and drive innovation that meets...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$85K - $110K *

Develop engaging, platform-native content that connects healthcare insights with audiences. Collaborate with teams to create innovative social media strategies, transforming complex information into r...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$72K - $104K *

Unlock your potential by delivering exceptional customer support in veterinary care. Engage with clients, resolve inquiries, and ensure compliance with industry standards while collaborating with inte...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Alabama?question toggle

    Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.

  • Which Alabama cities have high-paying professional jobs?question toggle

    Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.

  • Are the Alabama jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.

  • How can I find a $100K+ job in Alabama?question toggle

    Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.

  • Do Alabama jobs listed on Ladders require in-person work?question toggle

    Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.