Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.
Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.
High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.
Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.
Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.
Senior Director, DMPK Project Leader
$177K - $338K *
Champion DMPK project leadership by ensuring high-quality data delivery and supporting drug candidate progression through innovative modeling and cross-functional collaboration in a dynamic biotech en...
Reposted 3 days ago
Clinical Application Specialist
$80K - $90K *
Shape the future of Cell and Gene Therapy by providing expert application support, driving customer integration, and enhancing product utilization through collaboration and technical guidance across t...
3 weeks ago
Vice President, Global Supply Chain
$272K - $340K *
Lead the charge in shaping a global supply chain strategy that ensures seamless delivery of clinical and commercial products. Build a high-performing team and foster partnerships to meet regulatory st...
2 weeks ago
Sales Representative, Pain - Fresno, CA
$72K - $108K *
Unlock potential by developing strategic business plans and conducting impactful sales presentations. Achieve sales goals while fostering relationships and ensuring compliance with ethical practices i...
Today
Senior Director, Observational Research, CPSO
$204K - $276K *
Lead the charge in global observational research, driving clinical operational strategy and execution. Collaborate with cross-functional teams to ensure quality and efficiency in evidence generation t...
Today
$150K - $180K *
Join a team that's redefining scientific data management in drug discovery. Lead the scientific data team, bridging scientists and engineers to ensure data integrity, quality, and innovative solutions...
3 weeks ago
Manager, Regional Sales - Specialty (Penn-Erie)
$149K - $187K *
Drive regional sales success by leading a team of Territory Sales Managers, fostering a culture of accountability and collaboration, and executing strategic initiatives to achieve performance targets...
2 weeks ago
$144K - $173K *
Shape the future of pharmaceutical media by leading client strategy and integrated media delivery. Drive audience engagement, manage high-impact relationships, and leverage data insights to achieve me...
2 weeks ago
Healthcare Program & Project Manager (Remote)
$80K - $95K *
Transform healthcare initiatives by leading projects from inception to completion. Coordinate teams, manage timelines, and ensure clear communication to drive organizational priorities and deliver mea...
Yesterday
Director, Chronic Practice Liaison - Remote
$126K - $210K *
Lead strategic initiatives to enhance referral growth and provider engagement across chronic therapy markets. Drive collaboration among cross-functional teams to optimize patient progression and deliv...
3 weeks ago
Senior Account Manager, Med Affairs
$90K - $105K *
Collaborate with clients and teams to manage projects, expectations, and delivery, ensuring high standards and strategic growth in a fast-paced medical affairs environment. Leverage experience to iden...
Reposted 1 week ago
Supply Chain Contracting Manager- GPO
$96K - $118K *
Join a dynamic team to develop and manage supply chain contracting strategies that optimize costs and enhance value for member pharmacies. This role involves supplier negotiations, category performanc...
2 weeks ago
Senior Scientist, Safety Assessment and Investigative Toxicology
$66K - $189K *
Innovate analytical strategies to enhance toxicology assessments, ensuring compliance and data integrity. Collaborate across teams to drive project success and influence decision-making through advanc...
4 days ago
Senior Safety Physician - CNS (remote)
$222K - $356K *
Unlock your potential as a Senior Safety Physician, leading safety oversight for late-stage CNS clinical development. Collaborate with cross-functional teams to drive risk management and regulatory su...
Reposted 2 weeks ago
Pharmacy Benefits Management (PBM) Underwriting, Senior Analyst
$46K - $122K *
Join a team that's redefining healthcare contracts by leveraging financial expertise and strategic negotiation skills to enhance client relationships and drive business success in a dynamic environmen...
2 days ago
Pharmacy Benefits Management (PBM) Underwriting, Senior Analyst
$46K - $122K *
Unlock potential by joining a strategic team that formulates pricing strategies and analyzes complex data modeling for financial profitability in a dynamic healthcare environment. Drive impactful clie...
Reposted 2 weeks ago
Sales Representative, Pain - Sacramento, CA
$72K - $108K *
Accelerate progress at driving sales growth through strategic territory management, effective customer engagement, and adherence to ethical practices while achieving quarterly goals and fostering stro...
Today
$260K - $270K *
Unlock your potential as a Psychiatrist, providing advanced outpatient care via virtual platforms. Collaborate with multidisciplinary teams to deliver comprehensive treatment for diverse psychiatric c...
1 week ago
Corporate Communications Manager
$127K - $159K *
Transform corporate communications by crafting compelling content that enhances reputation, engages employees, and supports strategic initiatives. Collaborate across teams to manage projects and ampli...
Reposted 2 days ago
Manager, Supply Planning and Logistics
$100K - $120K *
Lead the charge in managing supply chain and logistics operations, ensuring accurate inventory control and timely shipments. Collaborate with internal and external partners to optimize processes and s...
2 days ago
$180K - $220K *
Lead the charge in providing comprehensive medical care to diverse patient populations, ensuring accurate diagnoses, effective treatments, and patient education while collaborating with healthcare tea...
3 weeks ago
21GRAMS- VP, Medical Strategy Director
$180K - $195K *
Elevate healthcare marketing by transforming complex science into impactful strategies. Lead multidisciplinary teams to inspire creativity, drive behavior change, and build trusted client relationship...
Reposted 2 weeks ago
$90K - $110K *
Transform complex clinical data into compelling copy that resonates. Collaborate with cross-functional teams to create impactful healthcare campaigns, ensuring accuracy and brand voice across diverse...
2 weeks ago
$143K - $203K *
Manage and lead global trade compliance operations, ensuring adherence to import/export regulations and fostering collaboration across teams to enhance efficiency and compliance...
Reposted 3 weeks ago
$88K - $105K *
Tackle strategic leadership in QC for raw materials, ensuring timely and compliant laboratory operations through effective resource management, team development, and regulatory adherence. Drive cross...
Reposted 3 weeks ago
What types of $100K+ jobs can I find in Alabama?
Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.
Which Alabama cities have high-paying professional jobs?
Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.
Are the Alabama jobs on Ladders vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.
How can I find a $100K+ job in Alabama?
Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.
Do Alabama jobs listed on Ladders require in-person work?
Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.