Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.
Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.
High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.
Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.
Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.
$80K - $95K *
Engage with patients as a Virtually Integrated Care RN, providing essential remote support and care coordination. Utilize advanced clinical skills to assess needs, develop care plans, and enhance pati...
3 days ago
$180K - $220K *
Transform healthcare delivery by providing expert diagnosis and treatment to military personnel and their families. Lead quality initiatives and ensure continuity of care in a dynamic clinical environ...
2 days ago
$100K - $160K *
Lead critical evaluations of biological risks, mentor junior specialists, and ensure high-quality labeling for AI safety classifiers in a dynamic life-sciences environment focused on biodefense and bi...
3 days ago
HCP Personal Marketing Lead - Epilepsy
$190K - $214K *
Lead HCP personal promotion strategy, developing and optimizing initiatives that engage healthcare professionals. Collaborate cross-functionally to ensure compliance and effectiveness in promotional t...
3 days ago
Principal, Data Governance Platforms
$149K - $224K *
Shape the future of data governance by leading the design and implementation of enterprise platforms that ensure data integrity, quality, and compliance across the organization, while collaborating wi...
2 weeks ago
Senior Manager, Third Party Data Governance
$120K - $145K *
Shape the future of data governance by leading a team to manage third-party data compliance, ensuring operational excellence and regulatory adherence while fostering collaboration across business unit...
Yesterday
Senior Budget Administrator - Clinical Trials
$100K - $161K *
Advance your career by coordinating clinical trial budgets and coverage analyses. Collaborate with stakeholders to ensure compliance and cost efficiency while mentoring junior staff and enhancing admi...
1 week ago
Sr. Director, Scientific Affairs
$181K - $225K *
Lead the charge in operationalizing complex clinical studies globally, collaborating with cross-functional teams to enhance proposal development and manage global lab relationships, ensuring strategic...
3 weeks ago
Sr. Director, Scientific Affairs
$181K - $225K *
Lead the charge in advancing scientific operations within a dynamic team, driving global lab relationships and supporting complex clinical studies. Collaborate across functions to ensure strategic, op...
3 weeks ago
APP (NP/PA) Primary Care Inbox Management (remote)
$119K - $134K *
Partner with us to enhance patient care by supporting primary care teams remotely. Collaborate with on-site providers to manage patient needs effectively, ensuring seamless communication and coordinat...
1 week ago
$110K - $130K *
Join a team that's dedicated to creating impactful medical education content for healthcare providers and patients. Collaborate closely with scientific and account teams to deliver high-quality materi...
Reposted 2 days ago
Applied AI Scientist IV - Healthcare, LLM/SLM, RAG experience
$113K - $197K *
Shape the future of healthcare by leading AI initiatives that enhance operations and patient outcomes. Drive innovation, mentor teams, and establish technical standards across machine learning, NLP, a...
3 weeks ago
Sr Area Business Director, West
$160K - $190K *
Lead the charge in driving growth by managing a high-performing sales team, collaborating across functions, and executing strategic initiatives to enhance commercial success in the Hematology sector...
Yesterday
Key Account Manager - Baltimore, MD
$170K - $205K *
Transform sales strategies by driving key account growth and fostering relationships in the healthcare sector. Collaborate cross-functionally to establish a strong foundation for a new kidney transpla...
3 weeks ago
Business Development Director I, Early Drug Development
$80K - $120K *
Shape the future of Crop Protection & Chemicals by driving sales and fostering client relationships. Utilize strategic insights and collaboration to achieve targets and expand market presence while ma...
Reposted 1 week ago
Senior/Staff AI Scientist, Antibody Design
$150K - $180K *
Transform innovative protein design through advanced AI techniques, enhancing antibody drug discovery. Collaborate across disciplines to maximize efficiency and impact, while leading research that set...
Reposted 4 weeks ago
Regional Account Manager-Eastern Midwest Region
$186K - $234K *
Grow your career by driving sales and building relationships in the neurology and rare disease sectors. Collaborate with healthcare professionals to enhance patient care and achieve sales targets whil...
3 weeks ago
Rare Hematology Thought Leader Liaison
$146K - $211K *
Transform the landscape of hematology by engaging KOLs, driving market development, and executing strategic initiatives to enhance patient care and foster collaboration across multidisciplinary teams...
Reposted 2 weeks ago
$100K - $130K *
Champion growth and build lasting partnerships by driving sales for custom corrugated packaging in North Alabama, Eastern Mississippi, and South Tennessee. Leverage industry insights and customer rela...
Reposted 3 weeks ago
Sr. CTM/Associate Director, QED Alliance support
$145K - $177K *
Join a team that's dedicated to advancing clinical trials for rare diseases. As a Senior Clinical Trial Manager, you'll lead operational execution, ensuring compliance and quality while fostering stro...
3 weeks ago
$116K - $145K *
Join a dynamic team to design and implement cloud security solutions, enhancing information security and compliance while mitigating cyber threats across the organization. Drive innovation and improve...
Reposted 4 weeks ago
Senior Manager, Contract Manufacturing
$138K - $145K *
Transform your career by overseeing contract manufacturing operations, ensuring quality and efficiency across diverse product formats. Collaborate with cross-functional teams to drive improvements and...
1 week ago
$100K - $130K *
Support the financial planning and analysis for Executive Leadership, encompassing budgeting, forecasting, and reporting. Collaborate cross-functionally to drive profitability through data-driven insi...
Reposted 2 weeks ago
Urgent Care Nurse Practitioner / Physician Assistant - Phenix City, AL | Up to $10K Sign-On Bonus
$114K - $187K *
Unlock potential by providing high-quality urgent care as a Nurse Practitioner or Physician Assistant. Engage with patients, perform procedures, and collaborate with a dedicated team in a supportive c...
1 week ago
$175K - $200K *
Transform compliance within a dynamic enterprise by designing and overseeing an effective Ethics and Compliance Program that aligns with regulations and promotes enterprise growth. Drive culture and a...
Reposted 2 days ago
What types of $100K+ jobs can I find in Alabama?
Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.
Which Alabama cities have high-paying professional jobs?
Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.
Are the Alabama jobs on Ladders vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.
How can I find a $100K+ job in Alabama?
Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.
Do Alabama jobs listed on Ladders require in-person work?
Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.