Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.
Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.
High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.
Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.
Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.
Clinical Trial Liaison (Oncology)
$100K - $120K *
Accelerate progress at clinical sites by enhancing patient recruitment strategies and supporting Oncology studies. Collaborate with teams to optimize enrollment processes and ensure effective communic...
2 days ago
$120K - $145K *
Lead cross-functional teams to develop and execute a strategic product roadmap, integrating market insights and performance metrics to drive customer-centric solutions in the diagnostics and genomics...
3 weeks ago
Senior Legal Counsel, Supply Chain Procurement and Operations NA
$150K - $180K *
Empower your career by serving as a legal partner in procurement and supply chain, providing expert guidance and support in contract negotiation, vendor relations, and operational risk management acro...
Reposted 3 days ago
Sr Account Manager, Industrial Water, NA
$120K - $140K *
Partner with us to drive growth in industrial accounts, leveraging your sales expertise to expand relationships and deliver innovative water treatment solutions that meet the needs of our customers an...
Reposted 3 days ago
Territory Leader: St. Louis, Missouri
$80K - $95K *
Grow your career in pharmaceutical sales by building relationships in dermatology. This role involves extensive travel to engage with healthcare professionals, promote products, and achieve sales goal...
1 week ago
Senior Bioinformatics & Genomics Data System Engineer
$113K - $142K *
Elevate your career by joining our dynamic team to design, develop, and optimize bioinformatics software tools and systems, ensuring robust functionality and compliance in a fast-paced, innovative env...
Yesterday
Deputy Chief of Party II, Technical, Continuity of Integrated Health Services
$95K - $117K *
Champion integrated health initiatives across multiple countries, providing strategic oversight and leadership for malaria, maternal health, and infectious disease programs. Ensure quality interventio...
4 weeks ago
$100K - $120K *
Champion a dynamic sales environment by leveraging your network and maximizing lead sources to drive success. Collaborate with a motivated team, embody integrity, and achieve exceptional results in th...
2 days ago
$100K - $120K *
Drive your career forward as a Loan Officer, leveraging your network and sales skills to maximize leads and earnings. Join a dynamic team focused on integrity and excellence, where your contributions...
2 days ago
Director, GCP Inspection Management- Americas
$172K - $232K *
Lead the GCP Inspection Management team to ensure inspection readiness and compliance. Oversee strategy development, cross-functional collaboration, and risk mitigation for successful regulatory inspe...
3 weeks ago
$130K - $150K *
Champion clinical project success by leading operations, training teams, and ensuring compliance. Drive strategic planning and risk management while overseeing site performance and fostering collabora...
1 week ago
Account Specialist, Des Moines, IA
$160K - $192K *
Optimize commercial performance by engaging healthcare providers and driving product adoption. Collaborate with cross-functional teams to support launches and enhance patient access to innovative ther...
1 week ago
Associate Contracts Manager - FSP
$68K - $103K *
Champion contract negotiation and management, ensuring timely delivery of legal agreements and compliance with project timelines. Collaborate closely with clinical teams across North America and Europ...
Reposted yesterday
Associate Contracts Manager - FSP
$68K - $103K *
Join a team that's enhancing clinical research by drafting and negotiating diverse agreements, ensuring compliance with timelines, and collaborating with global stakeholders to achieve successful proj...
Reposted 2 days ago
RN Operations Manager, One Medical Operations , Virtual Care Operations
$74K - $129K *
Elevate healthcare delivery by managing operations for a nationwide virtual medical team. Collaborate with leaders to optimize patient care, drive performance improvements, and implement innovative wo...
2 weeks ago
Senior Director, Contact Center
$150K - $180K *
Lead the future of patient experience by driving strategic initiatives and operational excellence in a high-volume healthcare contact center. Collaborate with cross-functional teams to enhance service...
Reposted 2 days ago
Principal Scientist/Associate Director, Translational Medicine
$190K - $210K *
Collaborate with cross-functional teams to drive clinical biomarker strategy and execution, translating discovery insights into actionable approaches that enhance patient outcomes in early neuroscienc...
6 days ago
Manager, Network Management (National Health Systems)
$54K - $159K *
Champion contract negotiations by driving initiatives, cultivating relationships, and ensuring compliance with performance goals. Leverage expertise to support cost-saving strategies and enhance cross...
Reposted 2 days ago
Director, Global Real-World Evidence & Health Outcomes Scientist, Oncology
$204K - $340K *
Lead the charge in generating impactful real-world evidence to support oncology products, ensuring alignment with market needs and regulatory requirements while collaborating across teams to drive evi...
1 week ago
Clinical Scientist - Oncology - Home-based anywhere in the US - FSP
$110K - $130K *
Elevate your career by supporting clinical studies through scientific expertise, operational delivery, and compliance. Collaborate with cross-functional teams and stakeholders to ensure successful tri...
4 weeks ago
Expert Data Scientist, Fraud Risk Detection
$120K - $145K *
Engineer innovative fraud detection models and features to identify high-risk activities while ensuring a seamless experience for legitimate customers. Collaborate with teams to translate insights int...
Yesterday
$250K - $500K *
Engage in transformative wound care as a Family Medicine Physician, leading initiatives in skilled nursing facilities. Utilize advanced techniques to enhance patient healing and collaborate with a ded...
3 days ago
$250K - $500K *
Join a team that's transforming patient care through advanced wound healing techniques. Collaborate in skilled nursing facilities, providing comprehensive treatment for chronic and complex wounds whil...
1 week ago
Market Manager, Outlying areas
$106K - $132K *
Drive local market execution and performance by collaborating with teams, leveraging data for growth, and managing distributor relationships to ensure alignment with strategic goals and operational ex...
Reposted 3 weeks ago
$90K - $100K *
Join a team that's redefining accounting excellence by managing month-end closes, revenue recognition, and international audits. Leverage your CPA expertise to enhance financial integrity and drive pr...
2 weeks ago
What types of $100K+ jobs can I find in Alabama?
Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.
Which Alabama cities have high-paying professional jobs?
Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.
Are the Alabama jobs on Ladders vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.
How can I find a $100K+ job in Alabama?
Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.
Do Alabama jobs listed on Ladders require in-person work?
Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.