Explore $100K+ Jobs in Alabama

Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.

Where to Find Professional Jobs in Alabama

Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.

Industries and Roles

High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.

Find the Right Alabama Opportunity

Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.

Advance Your Career in Alabama

Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.

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$46K - $122K *

Champion operational excellence and relationship management for healthcare partners. Collaborate across teams to drive strategic initiatives, enhance partner performance, and oversee issue resolution...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$90K - $110K *

Elevate patient care by enhancing pediatric endocrinology evaluations and services. Collaborate with families to provide comprehensive outpatient care, ensuring adherence to safety standards while man...

1 week ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$174K - $203K *

Empower clinical innovations by leading statistical strategies in oncology trials. Collaborate with cross-functional teams to design studies, analyze data, and support regulatory submissions, ensuring...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$90K - $130K *

Drive legal excellence by managing contracts and compliance for healthcare units. Collaborate with teams to navigate technology agreements and uphold healthcare laws, ensuring business success and ris...

RemoteRemote

1 month ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$105K - $125K *

Pioneer the development of robust software solutions in eDiary and clinical data platforms, leveraging modern technologies to enhance patient engagement and ensure regulatory compliance while collabor...

United StatesRemote

Reposted 6 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$180K - $215K *

Drive regional success by leading launch execution and building high-performing teams. Foster customer relationships and ensure alignment with corporate goals in a fast-paced, entrepreneurial environm...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$180K - $215K *

Tackle the challenge of launching a groundbreaking product by leading a high-performing sales team, driving regional execution, and fostering key customer relationships in a dynamic, fast-paced enviro...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Shape the future of patient care by delivering comprehensive assessments, implementing care plans, and collaborating with healthcare teams to ensure optimal outcomes and safety for all patients. Join...

Reposted today

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Champion animal health by delivering exceptional medical and surgical care in a collaborative environment. Join a passionate team dedicated to enhancing the well-being of companion animals while pursu...

Today

  •   Less than 5 years exp.  •   Healthcare

$134K - $306K *

Elevate customer engagement by developing and executing strategic study plans, leading cross-functional teams, and ensuring successful project delivery in the rare disease therapeutic area...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$97K - $104K *

Join a team that's dedicated to enhancing patient care through effective leadership and innovative program development in a dynamic rehabilitation environment. Oversee clinical operations, manage staf...

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $95K *

Drive comprehensive legal support across diverse business functions, managing contracts, insurance, and litigation. Collaborate with cross-functional teams to ensure compliance and facilitate growth i...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Real Estate & Construction

$87K - $110K *

Engage with customers to ensure their success through onboarding, training, and support. Build strong relationships, manage inquiries, and collaborate with teams to enhance customer satisfaction and d...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Deliver comprehensive psychological assessments and evidence-based interventions, guiding treatment plans for complex cases. Collaborate with interdisciplinary teams and supervise trainees while enhan...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$100K - $150K *

Transform the future of business development by building strategic partnerships across key professional services. Drive growth through relationship-building and co-closing deals, while shaping a natio...

RemoteRemote

3 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$80K - $95K *

Empower clinical teams by leading strategic initiatives in informatics, optimizing workflows, and enhancing technology integration to improve healthcare outcomes and operational efficiency across vari...

1 month ago

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$100K - $140K *

Drive innovative media strategies for healthcare clients, leveraging audience insights and performance data. Collaborate with cross-functional teams to enhance planning processes and deliver impactful...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$105K - $150K *

Transform healthcare insights by leading client engagements with real-world data. Drive business development and project delivery while building long-term client relationships in a dynamic, hybrid wor...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$83K - $222K *

Innovate your career with a Senior Epic Analyst role focused on designing and optimizing Epic solutions for population health and care coordination, while mentoring junior analysts and collaborating w...

RemoteRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$120K - $145K *

Unlock product potential by leading the development of innovative food safety solutions. Collaborate with cross-functional teams to address complex industry challenges and drive scalable product strat...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$90K - $110K *

Analyze healthcare data to enhance clinical insights and improve medication use. Collaborate with cross-functional teams to develop analytics tools and real-world evidence studies, driving better heal...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Manage diverse legal matters in a dynamic industrial environment, providing strategic support across commercial contracts, regulatory compliance, and corporate governance while collaborating closely w...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Energy & Utilities

$80K - $95K *

Lead the seamless delivery of services to enhance customer satisfaction. Collaborate with a team of technicians to tackle challenges, drive innovation, and ensure high-quality service in a fast-paced...

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$265K - $300K *

Shape the future of neurodegenerative disease diagnostics by leading scientific strategy, driving research programs, and building expert networks to establish industry leadership in innovative solutio...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Business Services

$120K - $145K *

Unlock potential by leading pre-sales technical strategies that align solutions with client needs, driving revenue growth and retention through collaboration with sales teams and delivering tailored p...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Alabama?question toggle

    Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.

  • Which Alabama cities have high-paying professional jobs?question toggle

    Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.

  • Are the Alabama jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.

  • How can I find a $100K+ job in Alabama?question toggle

    Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.

  • Do Alabama jobs listed on Ladders require in-person work?question toggle

    Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.