Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.
Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.
High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.
Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.
Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.
Business Analyst (NCPDP) - Remote
$95K - $115K *
Champion innovative solutions as a Business Solutions Analyst, collaborating with healthcare organizations to drive strategic initiatives and operational excellence across diverse projects and deliver...
4 weeks ago
Head of Analytical Development, Pulmovant
$160K - $200K *
Lead the charge in analytical development, overseeing drug substance and product strategies. Collaborate across teams to ensure compliance and performance, while mentoring a high-performing analytical...
2 weeks ago
Regulatory Affairs Consultant - Regulatory Generalist
$100K - $120K *
Take ownership of regulatory support for pharmaceutical programs, managing IND and NDA submissions, health authority interactions, and lifecycle maintenance. Collaborate with cross-functional teams to...
3 weeks ago
Clinical Genomics Advanced Practice Provider
$110K - $130K *
Unlock potential by joining a dynamic Clinical Oncology Team, where you'll leverage your oncology and genomics expertise to enhance point-of-care products, drive clinical workflows, and support person...
1 week ago
Director / Senior Director / Executive Director, Regulatory Affairs
$210K - $275K *
Transform regulatory affairs in oncology by leading strategic submission initiatives and cross-functional collaborations, ensuring compliance and quality for impactful development programs. Drive regu...
Reposted today
Nurse Practitioner Primary Care
$90K - $110K *
Transform patient care by providing direct support in long-term facilities. Collaborate with healthcare teams to deliver quality assessments, treatment plans, and education while ensuring compliance w...
4 weeks ago
Corporate Talent Acquisition Manager
$90K - $110K *
Shape the future of talent acquisition by leading a dynamic team to attract top executives and enhance recruitment strategies in a large, multifaceted organization, ensuring a high-quality candidate e...
2 weeks ago
Director, Medical Science Liaison (East)
$148K - $222K *
Drive clinical adoption and enhance partnerships by leading a high-performing Medical Science Liaison team. Collaborate with sales and medical teams to educate stakeholders, influence decision-making...
1 week ago
$100K - $125K *
Join our dynamic finance team as you drive margin and profitability through detailed analysis and strategic insights. Collaborate with senior leadership to transform data into actionable initiatives t...
1 week ago
Strategic Account Executive- Inventory Services
$94K - $125K *
Empower your career with an impactful role driving sales of complex supply chain solutions in healthcare. Engage C-suite executives, manage strategic accounts, and address industry challenges to deliv...
Reposted 4 weeks ago
Medical Assistant II & Phlebotomy Technician
$66K - $93K *
Advance patient care by providing clinical and clerical support, performing phlebotomy tasks, and ensuring smooth workflow within the team. Collaborate effectively to implement medical plans and enhan...
2 days ago
$110K - $130K *
Unlock potential by leading communications strategy to enhance brand narrative, drive awareness and loyalty, and engage diverse stakeholders in a fast-paced environment that supports food waste reduct...
Reposted 3 weeks ago
$170K - $180K *
Transform the sales landscape by leading strategic initiatives that enhance performance management, forecasting, and accountability across the commercial organization, driving profitable growth and ac...
3 weeks ago
Senior Analyst, Medical Economics - UM Analytics (Remote)
$90K - $110K *
Drive impactful medical economics analysis by extracting and synthesizing data to identify trends, enhance financial performance, and support executive decision-making across healthcare operations and...
3 weeks ago
Claims Compliance Program Manager
$73K - $130K *
Lead the charge in overseeing claims compliance activities, enhancing operational quality, and ensuring audit readiness. Collaborate cross-functionally to identify gaps, monitor KPIs, and drive improv...
4 days ago
Executive Director of Product Management , Resiliency
$150K - $214K *
Join a team that's redefining healthcare product management through innovative supply chain solutions. Lead cross-functional initiatives and shape the future of resilience in healthcare with strategic...
Reposted 4 weeks ago
$78K - $106K *
Transform client payment policies by ensuring accuracy and compliance. Engage with internal and external teams to manage medical policy updates, conduct analyses, and enhance client relationships whil...
2 weeks ago
$229K - $310K *
Drive project management and business development to enhance operational efficiency in life sciences R&D, while leading diverse teams and ensuring profitability through strategic customer engagement a...
Reposted 4 days ago
Primary Care Physician (Mobile, AL)
$200K - $250K *
Join a dedicated team as a Primary Care Physician, enhancing patient care through a collaborative, value-based model focused on seniors. Leverage your expertise to improve outcomes and provide a conci...
1 week ago
Clinical Account Specialist HS - Mobile
$132K - $174K *
Drive demand for innovative dermatology solutions by building relationships with healthcare professionals and ensuring patient access to therapies. Collaborate within a dynamic team to enhance patient...
4 days ago
Senior District Manager, Immunology Autoantibody Diseases, Gulf Coast
$120K - $145K *
Lead the charge in driving district performance and talent development in the immunology sector. Elevate strategy execution through cross-functional partnerships and advanced coaching, ensuring alignm...
1 week ago
Director, Cost of Care Solutions
$129K - $162K *
Unlock potential by leading enterprise-wide Cost of Care solutions. Drive scalability, optimize deployment, and enhance operational effectiveness across diverse markets, collaborating with stakeholder...
Reposted 1 week ago
$112K - $154K *
Lead the development and maintenance of Pharmacovigilance Risk Management Plans, ensuring pivotal safety documentation and compliance with global regulatory standards through collaboration and strong...
1 month ago
$105K - $202K *
Create innovative AI-powered healthcare products by transforming complex workflows into intuitive applications. Collaborate with cross-functional teams to deliver impactful user experiences and own fe...
3 weeks ago
Revenue Cycle Enterprise Partner
$133K - $191K *
Transform revenue cycle operations by leading strategic initiatives, optimizing performance, and fostering collaboration across business units to enhance service delivery and achieve organizational go...
1 week ago
What types of $100K+ jobs can I find in Alabama?
Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.
Which Alabama cities have high-paying professional jobs?
Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.
Are the Alabama jobs on Ladders vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.
How can I find a $100K+ job in Alabama?
Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.
Do Alabama jobs listed on Ladders require in-person work?
Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.