Explore $100K+ Jobs in Alabama

Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.

Where to Find Professional Jobs in Alabama

Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.

Industries and Roles

High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.

Find the Right Alabama Opportunity

Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.

Advance Your Career in Alabama

Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.

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$93K - $159K *

Advance your career by developing and standardizing Procurement processes that enhance compliance and efficiency. Collaborate with cross-functional teams to create clear documentation and governance p...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$100K - $162K *

Drive success by developing strategic sales plans and fostering relationships in your territory. Achieve sales goals through effective presentations and ethical practices while continuously enhancing...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$155K - $175K *

Serve as a key scientific partner in the field, driving prelaunch and launch strategies through trusted relationships, high-quality exchanges, and actionable insights to enhance product adoption and c...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$155K - $175K *

Drive impactful scientific engagement by building relationships with key stakeholders, translating clinical data into actionable insights, and ensuring successful product adoption in a dynamic prelaun...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Empower the clinical support team by coordinating complex cases, mentoring junior counselors, and enhancing protocols. Your expertise will drive effective communication and quality standards in geneti...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$229K - $458K *

Champion strategic growth initiatives in advanced manufacturing, driving business development and forging key partnerships. Collaborate with cross-functional teams to enhance service offerings and mee...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$175K - $237K *

Lead the charge in digital manufacturing innovation, transforming operational needs into practical solutions. Collaborate globally to enhance data, AI, and automation capabilities, ensuring safe and e...

United StatesRemote

3 days ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$180K - $215K *

Transform your career by leading regional sales efforts for a groundbreaking product. Drive performance, build a high-performing team, and engage with key healthcare providers in a fast-paced, entrepr...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$226K - $292K *

Lead strategic trade initiatives by collaborating with cross-functional teams to optimize distribution networks and channel strategies, ensuring alignment with market dynamics and compliance while dri...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Inspire growth in sales talent and elevate clinical performance through coaching and mentoring. Collaborate with leadership to design impactful training programs and build relationships that enhance t...

RemoteRemote

Reposted 1 month ago

  •   5 - 7 years exp.  •   Healthcare

$177K - $221K *

Drive the development and implementation of innovative clinical solutions, leading a technical team to deliver AI-enabled applications and analytics. Collaborate with stakeholders to ensure scalable...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$235K - $265K *

Bring your expertise to a pivotal leadership role, driving sales success and team performance in a dynamic environment. Lead product launches and foster collaboration to meet patient needs and achieve...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$148K - $205K *

Take ownership of complex PBM data integrations, ensuring accurate claims and eligibility processing while leading cross-functional teams and managing delivery timelines and risks...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Healthcare

$83K - $99K *

Optimize budget development for clinical change orders, collaborating across departments. Drive operational success by managing the budget lifecycle, ensuring accuracy, and resolving issues to support...

United StatesRemote

Reposted 4 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$78K - $88K *

Drive supplier relationships and manage product lines to optimize performance. Collaborate with teams on product development, analyze market trends, and execute pricing strategies to enhance value and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Champion statistical programming excellence in oncology clinical trials. Lead programming activities, collaborate with cross-functional teams, and ensure high-quality deliverables from study start-up...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$132K - $193K *

Unlock potential by leading the enterprise employee listening strategy, enhancing assessment science, and applying analytics to drive data-informed talent decisions. Collaborate with cross-functional...

RemoteRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$245K - $265K *

Drive strategic partnerships with Medical Experts in neurology, enhancing patient care through insights and collaboration. This field-based role requires strong relationship-building and cross-functio...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $230K *

Unlock potential by driving oncology product success through strategic relationships and innovative solutions. Lead efforts to enhance patient access and exceed performance goals while navigating a co...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$155K - $190K *

Manage the planning and execution of CMC operations across multiple development programs, ensuring alignment with regulatory milestones and efficient collaboration with cross-functional teams and CDMO...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$150K - $180K *

Unlock potential by guiding global regulatory strategies for innovative AI/ML healthcare solutions. Collaborate cross-functionally to navigate complex regulations while balancing innovation and patien...

United StatesRemote

Reposted 4 weeks ago

  •   11 - 15 years exp.  •   Healthcare

$80K - $100K *

Take ownership of complex desktop and mobile device support, ensuring high customer satisfaction. Administer enterprise management platforms and collaborate with teams to deliver effective technology...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$80K - $100K *

Transform endpoint management by leading complex support initiatives, ensuring seamless service delivery across diverse environments. Collaborate with teams to enhance user experience and optimize tec...

RemoteRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$285K - $325K *

Drive transformational patient impact by leading cross-functional teams and executing strategic drug development programs in an agile environment. Foster collaboration and accountability to deliver in...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$160K - $200K *

Join a team that's shaping the future of healthcare finance by overseeing all financial operations, ensuring efficiency and compliance, and leading the executive team to deliver high-quality services...

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Alabama?question toggle

    Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.

  • Which Alabama cities have high-paying professional jobs?question toggle

    Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.

  • Are the Alabama jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.

  • How can I find a $100K+ job in Alabama?question toggle

    Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.

  • Do Alabama jobs listed on Ladders require in-person work?question toggle

    Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.