Explore $100K+ Jobs in Alabama

Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.

Where to Find Professional Jobs in Alabama

Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.

Industries and Roles

High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.

Find the Right Alabama Opportunity

Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.

Advance Your Career in Alabama

Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.

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$130K - $211K *

Drive the design delivery for complex capital projects, influencing management and ensuring adherence to engineering standards while leading a diverse team of internal and external partners to achieve...

3 weeks ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$133K - $178K *

Advance R&D financial strategies by leading planning, reporting, and analysis. Collaborate across teams to evaluate investments and enhance financial processes, ensuring informed decision-making and o...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$150K - $170K *

Join a team that's transforming drug development through data science. Leverage your expertise to build predictive models and analytics, driving process improvements and technology transfer in a colla...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Drive data integrity and operational excellence by resolving complex payer data issues, collaborating across teams, and enhancing data quality for value-based care initiatives. Play a key role in opti...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$139K - $188K *

Unlock potential by leading regulatory writing for complex submissions, mentoring junior writers, and driving departmental initiatives. Collaborate with cross-functional teams to ensure compliance and...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Elevate member care by facilitating seamless transitions from hospital to home. Collaborate with healthcare teams to ensure safe discharges, reduce readmissions, and provide comprehensive support thro...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$99K - $118K *

Transform your career by leveraging your clinical and coding expertise to defend appeals for healthcare claims. This role demands independent analysis, strong communication, and proficiency in AI tool...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$162K - $195K *

Shape the future of cardiovascular care by driving the launch of a novel cardiac myosin inhibitor. Collaborate with healthcare professionals and internal teams to establish strategic relationships and...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$295K - $314K *

Drive strategic biostatistical leadership for clinical development programs, overseeing statistical activities, collaborating with cross-functional teams, and ensuring high-quality data analysis to su...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Transform the future of education and health as a visionary leader, overseeing academic operations, faculty development, and strategic initiatives in a dynamic department dedicated to special educatio...

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$100K - $120K *

Pioneer innovative leadership in a dynamic academic department, enhancing education and health through research, outreach, and teaching. Drive strategic initiatives, foster collaboration, and elevate...

1 week ago

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$175K - $215K *

Elevate the technology function by leading engineering, delivery, and operations. Collaborate closely with leadership to shape technical strategy, ship code weekly, and ensure high standards in a dyna...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Media

$71K - $107K *

Elevate patient care by delivering comprehensive nursing services in home settings. Collaborate with healthcare teams to ensure continuity of care, implement care plans, and maintain high standards of...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$71K - $107K *

Shape the future of home health care by providing exceptional nursing services, coordinating patient care, and collaborating with healthcare professionals to ensure quality outcomes and continuity of...

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$79K - $117K *

Deliver strategic leadership by optimizing patient billing processes to enhance the financial health of healthcare services, ensuring compliance with regulations while driving team performance and cus...

RemoteRemote

Reposted today

  •   5 - 7 years exp.  •   Hospitals & Medical Centers

$114K - $140K *

Help us drive sales and enhance patient care by leveraging your clinical expertise and sales acumen. As a key liaison, you'll promote innovative products and strategies while building strong relations...

3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$170K - $190K *

Empower innovation at the intersection of technology and law. Guide product, engineering, and compliance teams in navigating regulatory landscapes and mitigating risks related to AI and machine learni...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Information Technology

$150K - $230K *

Champion the promotion of oncology products, building strong relationships with healthcare professionals to enhance patient access and drive brand value in a competitive market. Lead strategic initiat...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$235K - $270K *

Drive your career forward by leading access strategies across the Central region. Manage key payer relationships and ensure launch readiness for rare disease products while collaborating with cross-fu...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$210K - $250K *

Drive transformative healthcare initiatives by leading a team of practitioners, optimizing clinical protocols, and enhancing patient care through innovative medical solutions in weight management and...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$130K - $217K *

Join a team that's driving innovation in pharmacy operations, managing complex initiatives, and enhancing business performance. Collaborate with senior leaders to deliver measurable impact and shape t...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$150K - $180K *

Drive impactful scientific communication by overseeing content development across therapeutic areas, ensuring strategic alignment with client goals while managing a team and collaborating with various...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Aerospace & Defense

$120K - $160K *

Drive brand awareness and product adoption by engaging healthcare professionals and stakeholders. Execute territory strategies, build relationships, and navigate access dynamics to establish trust and...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$130K - $160K *

Oversee the operational planning and execution of clinical trials, ensuring compliance with regulatory standards while managing cross-functional teams to meet project timelines, budgets, and quality o...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$140K - $175K *

Empower scientific innovation by collaborating within product pods to develop and evaluate real-world evidence agents. Drive impactful research and ensure scientific rigor while partnering with indust...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in Alabama?question toggle

    Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.

  • Which Alabama cities have high-paying professional jobs?question toggle

    Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.

  • Are the Alabama jobs on Ladders vetted?question toggle

    Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.

  • How can I find a $100K+ job in Alabama?question toggle

    Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.

  • Do Alabama jobs listed on Ladders require in-person work?question toggle

    Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.