Discover high-paying professional opportunities across Alabama with Ladders. Browse vetted jobs with salaries of $100,000 or more, from leadership and specialized individual-contributor roles to executive positions. Whether you’re considering a move or advancing your career close to home, explore openings in Alabama’s major employment centers and growing industries.
Alabama offers career opportunities in cities and regions throughout the state. Huntsville is known for aerospace, defense, engineering, and technology employers. Birmingham has a broad business community, including healthcare, finance, and professional services. Mobile supports opportunities in industries such as aerospace, logistics, manufacturing, and maritime commerce. Roles may also be available in Montgomery, Tuscaloosa, and other Alabama communities.
High-paying Alabama jobs can span technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Depending on the employer and location, you may find opportunities for experienced engineers, technology leaders, healthcare professionals, finance specialists, and business executives. Job availability and salary requirements vary by listing.
Use Ladders to search for roles that match your experience, desired location, and career goals. Review each listing for compensation, responsibilities, qualifications, and work arrangement. Since openings change, check back regularly and tailor your resume to highlight measurable results, leadership, and specialized skills relevant to the role.
Whether you’re targeting a position in Huntsville’s technology and aerospace ecosystem, Birmingham’s corporate and healthcare landscape, or another part of the state, Ladders can help you explore vetted professional jobs paying $100,000 or more. Browse current Alabama listings to find a role aligned with your expertise and next career step.
Senior Manager, Program Management Operations
$143K - $179K *
Lead cross-functional initiatives, optimizing governance and operational readiness for programs. Collaborate with stakeholders to enhance portfolio execution, reporting, and PMO capabilities, driving...
Reposted today
Nurse Practitioner or Physician Assistant (Monroeville, AL)
$187K *
Empower patient care by delivering high-quality primary and palliative services. Collaborate with a diverse team to assess, diagnose, and treat patients, ensuring optimal health outcomes in a supporti...
3 days ago
Account Specialist (Peachtree City, GA)
$160K - $192K *
Drive commercial performance by engaging healthcare providers and executing territory plans. Collaborate with cross-functional teams to support product launches and ensure patient access to innovative...
5 days ago
Senior Director, Commercial Manufacturing
$180K - $200K *
Champion commercial manufacturing excellence by leading technical operations, ensuring on-time delivery of drug products and APIs, and collaborating with regulatory teams to meet compliance and perfor...
4 weeks ago
Group Account Supervisor - Healthcare and Pharmaceutical Advertising
$100K - $139K *
Lead a dynamic account team to drive strategic growth and client relationships. Oversee financial management and tactical execution while fostering team development and ensuring high-level client sati...
2 weeks ago
Senior Oncology Account Manager, Kansas City
$150K - $230K *
Grow your career with a dynamic team focused on oncology solutions, driving product promotion and building relationships with key stakeholders to enhance patient access and care in a competitive bioph...
1 week ago
Case Manager - Registered Nurse - South Region
$60K - $129K *
Partner with us to enhance health outcomes through a comprehensive, collaborative case management approach, engaging with clients and healthcare providers to optimize care plans and ensure quality ser...
Reposted 1 week ago
Thought Leader Liaison, US Oncology, Northeast
$167K - $300K *
Elevate oncology marketing strategies by leading KOL engagement and advocacy initiatives. Utilize market insights to shape brand strategy and launch planning for innovative therapies, ensuring complia...
4 days ago
Associate Director, Compliance Field Commercialization, Lung
$177K - $221K *
Empower compliance excellence by leading the NSCLC field compliance program. Collaborate with cross-functional teams to identify risks, develop scalable solutions, and ensure adherence to regulations...
2 weeks ago
Sr. Sustainability Engineer - Radiopharmaceutical Manufacturing
$110K - $130K *
Innovate your career with a key role supporting the global launch and technical operations of radiopharmaceuticals, driving compliance, quality initiatives, and collaboration with CDMOs while leading...
Reposted 1 week ago
Lead Director, Medical Benefit Portfolio Product Management (Central Region)
$100K - $231K *
Unlock market potential by leading product strategy and execution for the Central Region. Drive portfolio performance, align cross-functional teams, and enhance customer value through innovative healt...
Reposted 1 week ago
Account Director, Promotional Medical Education
$100K - $120K *
Partner with us to drive strategic healthcare marketing initiatives. Lead client relationships, oversee peer-to-peer programs, and mentor team members to ensure compliance and achieve results while fo...
Reposted 2 weeks ago
$61K - $122K *
Optimize product delivery by bridging business needs and technical teams, leading requirement gathering, defining user stories, and ensuring alignment with stakeholders to enhance Epic EHR capabilitie...
Today
Account Specialist, Needham, MA
$160K - $192K *
Join a dynamic team to drive commercial performance and enhance patient access. Engage healthcare providers, support product launches, and collaborate with cross-functional partners to achieve sales g...
1 week ago
Staff Software Engineer - Biopharma Reporting and Specialty Analytics
$96K - $151K *
Join a team that's transforming healthcare by developing analytic products from clinical data. Collaborate in an agile environment to deliver insights that enhance efficacy and drive innovation in the...
Yesterday
Senior Manager, Drug Safety & Pharmacovigilance
$132K - $172K *
Lead pharmacovigilance operations and safety science initiatives, ensuring compliance and quality in drug safety reporting. Oversee vendor performance, manage safety data, and contribute to regulatory...
2 weeks ago
$80K - $95K *
Join a team that's dedicated to ensuring quality excellence through meticulous document control, product release oversight, and data analysis, while fostering a collaborative environment to drive cont...
3 weeks ago
Nurse Practitioner or Physician Assistant (Brewton, AL)
$187K *
Join a team that's dedicated to providing exceptional primary care to diverse patients. Utilize your clinical expertise to assess, diagnose, and treat chronic conditions while fostering trust and coll...
3 days ago
Account Specialist (Cleveland, OH)
$160K - $192K *
Join a team that's driving commercial success by engaging healthcare providers, building relationships, and supporting innovative therapies. Your expertise will be pivotal in executing business plans...
1 week ago
$160K - $192K *
Lead the charge in driving commercial performance by engaging healthcare providers, building relationships, and executing territory business plans to ensure patient access to innovative therapies and...
1 week ago
Account Specialist, Lafayette, IN
$160K - $192K *
Drive commercial performance by engaging healthcare providers and executing territory plans. Collaborate with cross-functional teams to support product launches and ensure patient access to innovative...
1 week ago
Senior Oncology Account Manager, Columbia
$150K - $230K *
Engage with key stakeholders to promote oncology products, build relationships, and drive brand value. Utilize market insights to develop strategic plans, ensuring patient access and compliance while...
1 week ago
Senior Director, US Marketing, Inborn Errors of Metabolism
$247K - $305K *
Support the strategic commercialization of rare disease therapies by leading marketing initiatives, collaborating cross-functionally, and optimizing brand strategies to enhance patient access and enga...
Reposted yesterday
Executive Director, Account Management
$255K - $310K *
Lead a high-performing team to execute market access strategies, optimize payer engagement, and enhance product positioning. Drive collaboration across stakeholders to ensure effective reimbursement a...
1 week ago
Senior Oncology Account Manager, Cleveland
$150K - $230K *
Drive impactful oncology product promotion by building strong relationships with key stakeholders. Leverage clinical expertise and market insights to exceed performance goals while ensuring patient ac...
1 week ago
What types of $100K+ jobs can I find in Alabama?
Listings may include senior and specialized roles in technology, engineering, healthcare, manufacturing, finance, operations, sales, and executive leadership. Available jobs depend on current employer openings.
Which Alabama cities have high-paying professional jobs?
Professional opportunities can be found in Huntsville, Birmingham, Mobile, Montgomery, Tuscaloosa, and other areas. The number and type of openings vary by location.
Are the Alabama jobs on Ladders vetted?
Ladders focuses on vetted professional jobs with salaries of $100,000 or more. Review each listing for its specific compensation details, qualifications, and other terms.
How can I find a $100K+ job in Alabama?
Search Alabama listings by role, location, and relevant keywords, then review the compensation and requirements for each opening. Keep your resume current and highlight experience and accomplishments that fit your target roles.
Do Alabama jobs listed on Ladders require in-person work?
Work arrangements vary by employer and position. Check each listing to see whether the role is on-site, hybrid, or remote and whether location-specific requirements apply.