Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$146K - $206K *

Unlock potential by leading software projects, collaborating with teams, and ensuring timely delivery while supporting product development and operational excellence in a dynamic environment...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$95K - $152K *

Transform project management by leading medium to large-scale E,F&I projects. Drive customer satisfaction and achieve financial targets while collaborating with cross-functional teams to ensure qualit...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Telecommunications & Hardware

$111K - $163K *

Join a team dedicated to driving successful IT project outcomes through effective management methodologies, ensuring on-time and on-budget completion while aligning with business goals and fostering c...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$139K - $235K *

Lead community growth initiatives by shaping strategies, enhancing member experiences, and driving engagement through integrated marketing efforts. Collaborate cross-functionally to foster meaningful...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$110K - $130K *

Transform partner relationships into measurable success by managing a strategic portfolio of technology and advisory partners. Collaborate across teams to drive growth, co-sell, and enhance operationa...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$125K - $150K *

Lead the charge in financial planning and analysis, driving strategic initiatives and cross-functional collaboration to enhance decision-making and operational effectiveness in a mission-driven enviro...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$120K - $145K *

Lead the charge in architecting and automating secure CI/CD pipelines and cloud infrastructure, ensuring compliance and resilience while delivering high-quality software through expert DevSecOps pract...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$90K - $110K *

Optimize the quality assurance process by leading data analytics and specification development. Drive actionable insights from complaints and non-conformance data while ensuring compliance across manu...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$130K - $150K *

Drive the pre-execution contract lifecycle for pharmacy and medical benefits, ensuring clear agreements and timely completion. Collaborate with cross-functional teams to enhance contracting processes...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$140K - $160K *

Innovate by leading global Credit & Collections operations, driving cash performance, and managing customer credit risk. Collaborate with cross-functional teams to enhance processes, ensure compliance...

United StatesRemote

Reposted 3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$138K - $165K *

Elevate your career by leading complex product initiatives across technical domains. Collaborate with cross-functional teams to drive strategic direction into actionable plans, ensuring measurable out...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$128K - $160K *

Drive operational excellence and customer satisfaction by managing services teams, optimizing project delivery, and enhancing client engagement strategies for government clients, ensuring alignment wi...

United StatesRemote

Reposted 5 days ago

  •   Less than 5 years exp.  •   Information Technology

$120K - $150K *

Innovate automated scoring solutions by leading a diverse team of experts. Drive research and development in natural language applications to enhance educational assessments and feedback mechanisms, e...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$75K - $90K *

Join a team that's dedicated to organic growth as you lead SEO strategies and initiatives. Collaborate with cross-functional teams, drive measurable performance, and optimize client accounts in divers...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Enterprise Technology

$115K - $125K *

Champion operational excellence by managing cross-regional teams, ensuring consistent performance standards, and facilitating effective agent execution. Drive strategic initiatives and resolve conflic...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$80K - $90K *

Drive revenue growth by establishing high-value partnerships, optimizing portfolio expansion, and securing contract renewals. Leverage data-driven strategies to enhance client relationships and positi...

Reposted today

  •   5 - 7 years exp.  •   Business Services

$93K - $125K *

Champion operational excellence as you support complex product programs, collaborating with engineers and partners. Drive data integrity, maintain documentation, and ensure seamless communication acro...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $200K *

Manage advanced product development programs for data center infrastructure, collaborating with cross-functional teams to drive comprehensive manufacturing strategies, optimize operations, and ensure...

RemoteRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $110K *

Shape your career by empowering sales teams with innovative enablement strategies. Collaborate across departments to enhance seller performance, drive revenue growth, and leverage AI tools for impactf...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Technical Services

$185K - $230K *

Empower patient access by leading reimbursement strategies in rare diseases. Collaborate cross-functionally to navigate complex pathways, educate providers, and support patients, ensuring compliance a...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$87K - $135K *

Unlock your potential by leading a dynamic Knowledge Management program that enhances IT support services, fosters collaboration, and drives efficiency for a large-scale enterprise environment. Make a...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $150K *

Elevate digital partnerships by driving growth and engagement through strategic planning and relationship management. Collaborate with cross-functional teams to optimize performance and expand technol...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Accelerate your career by driving analytics and operational excellence in a dynamic commercial environment. This role empowers you to enhance reporting, support strategic decisions, and collaborate cr...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Healthcare

$125K - $150K *

Shape the future of product marketing by bridging product and go-to-market teams. Drive impactful messaging, enablement, and strategies that resonate with audiences, ensuring alignment in a fast-paced...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $200K *

Discover innovative ways to engage audiences by leading voice and community strategies. Drive content standards, optimize performance with AI, and foster authentic connections across platforms while m...

United StatesRemote

3 days ago

  •   5 - 7 years exp.  •   Media

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.