Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$132K - $338K *

Lead the charge in embedding Responsible AI across the lifecycle, managing global teams, and architecting production-grade AI solutions while ensuring ethical standards and governance are met througho...

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$80K - $110K *

Lead the execution of R&D tax credit projects, managing client engagements from start to finish while ensuring compliance and accuracy in documentation and reporting. Collaborate with cross-functional...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Legal & Accounting

$120K - $145K *

Join a team that's dedicated to delivering innovative technical solutions. As a Senior Solutions & Implementation Manager, you'll engage with C-level executives and lead high-profile projects, ensurin...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$100K - $120K *

Accelerate progress at driving new client partnerships and revenue growth within a high-autonomy, results-driven sales environment. Own the complete sales cycle, leveraging networks to create strategi...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Business Services

$110K - $130K *

Drive complex project implementations by leading cross-functional teams, managing deliverables, and ensuring compliance. Leverage Salesforce expertise to optimize processes and foster client relations...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Information Technology

$130K - $160K *

Unlock potential by leading global compensation strategies across multiple regions. Collaborate with HR and business leaders to execute merit cycles, benchmark roles, and innovate with AI tools to enh...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$80K - $120K *

Engage clients by driving sales of Managed and Professional Services, identifying opportunities, and delivering tailored solutions. Cultivate relationships to exceed revenue targets while leveraging i...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Enterprise Technology

$130K - $163K *

Accelerate progress at expanding our portfolio by driving revenue and managing private label accounts while collaborating with cross-functional teams to create innovative, customer-centric solutions t...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Food & Beverages

$90K - $150K *

Join a team that's driving strategic sourcing initiatives in healthcare. Lead complex negotiations and sourcing events, ensuring compliance and value for member organizations while collaborating with...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Healthcare

$110K - $130K *

Elevate commercial performance by partnering with teams to translate strategies into actionable enablement. Drive measurable outcomes through effective training, tools, and continuous improvement acro...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$108K - $180K *

Join us in leading product strategy and execution for a diverse portfolio, enhancing Provider Contracting and Credentialing. Collaborate with cross-functional teams to drive innovation, improve custom...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$120K - $150K *

Reimagine brand identity and creative direction, leading a dynamic team to elevate packaging, campaigns, and content. Drive innovative storytelling and community experiences while collaborating across...

United StatesRemote

4 weeks ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Empower revenue operations by architecting and optimizing scalable GTM systems. Collaborate with cross-functional teams to translate complex business needs into automated solutions, ensuring seamless...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Information Technology

$100K - $120K *

Lead the charge in transforming healthcare analytics by building robust data models and dashboards. Collaborate with diverse stakeholders to deliver actionable insights, ensuring data quality and clar...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $149K *

Unlock potential by leading healthcare data analytics to enhance hospital quality performance and rankings. Collaborate with teams to design dashboards, mentor analysts, and present insights to execut...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Healthcare

$80K - $95K *

Shape the future of financial content by crafting engaging, SEO-driven copy that informs and converts. Collaborate with SEO experts and compliance teams to produce clear, compliant content that resona...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$99K - $232K *

Lead Salesforce CPQ and Revenue Cloud initiatives, guiding teams to enhance operational efficiency and achieve business goals through effective solution design and implementation, while fostering a cu...

4 weeks ago

  •   5 - 7 years exp.  •   Legal & Accounting

$209K - $239K *

Transform business strategies by leveraging analytics and AI to drive growth and profitability. Collaborate with cross-functional teams to enhance product offerings and optimize marketing efforts in a...

RemoteRemote

2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$116K - $145K *

Join a team that's redefining claims adjudication by leading the vision, strategy, and lifecycle of a comprehensive platform. Drive innovation across product, operations, and client-facing teams to de...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$162K - $225K *

Join a team that's shaping the future of fintech through M&A, fundraising, and strategic projects. Collaborate with executives to drive impactful decisions and build corporate development capabilities...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$109K - $140K *

Champion financial excellence by leading accounting and reporting for diverse legal entities. Drive process improvements, ensure compliance with GAAP, and develop a high-performing team while collabor...

1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$150K - $180K *

Lead the charge in providing strategic legal guidance for commercial agreements, balancing risk management with revenue growth. Collaborate with cross-functional teams to negotiate and optimize contra...

United StatesRemote

2 days ago

  •   8 - 10 years exp.  •   Enterprise Technology

$136K - $181K *

Take ownership of CRA management by leading teams, developing metrics, and ensuring compliance with monitoring standards. Drive continuous improvement and optimize effectiveness across the Site Manage...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$80K - $95K *

Champion client success by managing complex insurance placements, negotiating optimal coverage, and fostering key relationships in the insurance marketplace. Stay informed on industry trends to delive...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

$122K - $173K *

Champion the future of hardware operations by leading a dynamic team, overseeing installations, and ensuring optimal performance of cutting-edge infrastructure. Drive strategic initiatives and enhance...

3 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.