Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down

Sort By: Relevance

$85K - $110K *

Develop engaging, platform-native content that connects healthcare insights with audiences. Collaborate with teams to create innovative social media strategies, transforming complex information into r...

United StatesRemote

Reposted 3 weeks ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$128K - $153K *

Join a team that's shaping the future of technology by delivering impactful software solutions. Collaborate on innovative projects, optimize data operations, and enhance user experiences while support...

United StatesRemote

2 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$124K - $236K *

Reimagine your career by leading a dynamic team in financial advisory. Drive impactful projects with finance executives, enhance reporting processes, and foster client relationships while developing j...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$120K - $145K *

Join a dynamic team to drive the development of a cutting-edge marketplace, enhancing provider products and economic incentives while collaborating closely with engineering and operations to transform...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$90K - $110K *

Champion client success by leading complex implementations, managing risks, and ensuring operational readiness. Collaborate with executive stakeholders to deliver projects on time while maintaining hi...

RemoteRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Finance & Insurance

$150K - $180K *

Transform compensation and rewards at scale, ensuring fairness and clarity across global teams. Collaborate with leadership to design and implement effective pay structures, cycles, and equity guideli...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Elevate your career by leading demand generation strategies that drive pipeline growth in the public sector. Collaborate with sales and marketing teams to optimize campaigns, enhance performance, and...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$217K - $303K *

Innovate by building next-gen media infrastructure to enhance video/audio content processing and delivery. Collaborate with multidisciplinary teams to tackle complex challenges, ensuring high-quality...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Media

$80K - $100K *

Shape the future of medical communications by crafting high-quality, scientifically accurate content. Collaborate with diverse teams to deliver impactful resources that meet client needs while mentori...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$118K - $230K *

Lead data-driven growth strategies by collaborating with Marketing, Sales, and CX teams. Utilize advanced analytics and machine learning to optimize customer acquisition and retention, driving measura...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Take ownership of large-scale construction projects, managing stakeholders and ensuring compliance. Oversee project governance, track milestones, and enhance processes while fostering client relations...

United StatesRemote

4 days ago

  •   5 - 7 years exp.  •   Real Estate & Construction

$160K - $200K *

Unlock your potential as a strategic leader driving growth through innovative marketing strategies. Collaborate with teams to enhance demand generation and optimize performance, ensuring alignment wit...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Finance & Insurance

$129K - $177K *

Shape the future of profitability analysis by transforming complex data into actionable insights for senior leadership, driving strategic decisions in a dynamic, fast-paced environment with opportunit...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Enterprise Technology

$100K - $120K *

Empower enterprise clients by driving product adoption and success. As a key advisor, you'll manage relationships, develop strategic roadmaps, and ensure customer satisfaction while collaborating with...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$70K - $95K *

Join a team that's shaping the future of AI in international development. Lead market research initiatives to identify opportunities, analyze trends, and provide strategic insights that drive business...

United StatesRemote

6 days ago

  •   5 - 7 years exp.  •   Enterprise Technology

$144K - $189K *

Unlock potential by leading product innovation in clinical genomics. Shape tools for case management and data workflows, ensuring efficiency and quality while collaborating with lab directors and engi...

United StatesRemote

3 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$140K - $150K *

Reimagine data management as a Senior Technical Product Owner, leading cross-functional teams to drive product vision and execution. Oversee complex SQL Server systems and cloud-native applications, e...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Healthcare

$142K - $224K *

Unlock strategic partnerships by managing end-to-end contracting processes, ensuring optimal patient access through collaboration with internal teams and external stakeholders. Drive initiatives that...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$72K - $108K *

Shape the future of data analytics by designing and building a robust data layer in BigQuery. Collaborate with cross-functional teams to standardize metrics and enable self-service analytics, ensuring...

United StatesRemote

Reposted 2 weeks ago

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$125K - $169K *

Transform customer outcomes by leading a high-performing team dedicated to leveraging Samsara's solutions. Drive strategic growth while ensuring enterprise clients realize sustained value from their i...

United StatesRemote

Reposted 2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$124K - $165K *

Innovate the Federal and Defense marketing strategy by executing integrated, multi-channel programs that drive pipeline growth. Collaborate closely with sales leadership to engage diverse federal audi...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Lead complex product group initiatives, ensuring successful delivery through strategic planning, stakeholder engagement, and cross-team collaboration. Mentor program managers while driving transformat...

United StatesRemote

1 month ago

  •   8 - 10 years exp.  •   Retail & Consumer Goods

$132K - $338K *

Lead the charge in embedding Responsible AI across the lifecycle, managing global teams, and architecting production-grade AI solutions while ensuring ethical standards and governance are met througho...

3 weeks ago

  •   8 - 10 years exp.  •   Business Services

$80K - $110K *

Lead the execution of R&D tax credit projects, managing client engagements from start to finish while ensuring compliance and accuracy in documentation and reporting. Collaborate with cross-functional...

United StatesRemote

1 month ago

  •   Less than 5 years exp.  •   Legal & Accounting

$120K - $145K *

Join a team that's dedicated to delivering innovative technical solutions. As a Senior Solutions & Implementation Manager, you'll engage with C-level executives and lead high-profile projects, ensurin...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Finance & Insurance

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.