Explore $100K+ Jobs in Iowa

Find professional opportunities across Iowa with salaries of $100,000 or more. From Des Moines and Cedar Rapids to Iowa City, Davenport, and beyond, Ladders helps experienced professionals discover vetted roles that match their skills and career goals.

High-Paying Careers Across Iowa

Iowa employers hire experienced professionals in fields such as healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Available positions and compensation vary by employer, location, and experience, so explore listings to see which opportunities fit your background.

Where to Find Iowa Opportunities

Search jobs in major employment centers including Des Moines, Cedar Rapids, Iowa City, Davenport, and Sioux City, as well as remote and hybrid roles that may be available to candidates in Iowa. Use location and job-title filters to focus your search.

Find a Role That Fits Your Experience

Compare responsibilities, qualifications, and compensation details across openings. Keep your resume current, tailor applications to each position, and set up job alerts to stay informed when relevant high-paying jobs are posted.

Search Vetted Professional Jobs on Ladders

Ladders focuses on professional opportunities paying $100,000 or more. Browse Iowa listings to find your next career move and connect with roles suited to your expertise.

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$97K - $138K *

Help us shape the future of competitive intelligence by leading strategic initiatives that drive market insights and customer advocacy, enhancing our sales and marketing efforts while fostering strong...

United StatesRemote

2 weeks ago

  •   5 - 7 years exp.  •   Consumer Technology

$120K - $145K *

Drive innovation by designing async backend systems that integrate AI seamlessly, enabling scalable solutions for millions of businesses. Collaborate with a dynamic team to transform concepts into pro...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Shape the future of hotel technology by owning the end-to-end booking experience, bridging guest interactions and hotel-focused workflows to drive measurable business value through innovative solution...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Hospitality & Recreation

$150K - $180K *

Champion integrated marketing strategies to drive growth, enhance brand awareness, and support sales initiatives. Lead cross-functional teams in executing customer-centric programs that generate deman...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$110K - $130K *

Transform your career by leading full-cycle recruiting for GTM roles. Collaborate with executives to define hiring standards, build strong talent pipelines, and drive strategic hiring initiatives in a...

United StatesRemote

3 weeks ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $180K *

Join a team that's redefining the buyer experience in B2B software. As a Principal Product Manager, you'll lead strategy, drive product delivery, and enhance buyer trust across multiple platforms, ens...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Enterprise Technology

$120K - $145K *

Innovate enterprise architecture solutions that enhance business operations. Collaborate with IT and business teams to tackle complex challenges, ensuring scalable, secure, and efficient systems acros...

United StatesRemote

3 weeks ago

  •   8 - 10 years exp.  •   Information Technology

$83K - $110K *

Lead operational excellence by managing complex training programs and enhancing processes for a statewide initiative, ensuring effective communication and client engagement while fostering a high-perf...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Business Services

$200K - $250K *

Pioneer innovative solutions in enterprise healthcare by owning product development, enhancing EMR integrations, and streamlining implementations to ensure rapid adoption and customer satisfaction acr...

United StatesRemote

4 weeks ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $138K *

Optimize sales strategies and drive growth in the US Academic market by partnering with teams to deliver innovative research solutions, enhance customer relationships, and achieve sales targets while...

United StatesRemote

4 weeks ago

  •   5 - 7 years exp.  •   Information Technology

$180K - $252K *

Take ownership of strategic finance initiatives, driving growth through collaboration and analysis. Lead cross-functional teams to execute high-impact projects that align with organizational goals and...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Media

$94K - $266K *

Lead end-to-end SAP PP solution architecture for complex S/4HANA programs. Collaborate with cross-functional teams, mentor consultants, and advise executives on manufacturing strategies and Industry 4...

Today

  •   5 - 7 years exp.  •   Business Services

$160K - $220K *

Join us to lead and expand our Analytics practice, driving data insights and marketing strategies while managing a talented team in a dynamic and evolving digital landscape...

RemoteRemote

Reposted yesterday

  •   8 - 10 years exp.  •   Media

$128K - $160K *

Manage the integration and presentation of financial data within a leading market intelligence platform. Collaborate with cross-functional teams to enhance search and agentic capabilities, ensuring da...

United StatesRemote

Reposted 3 days ago

  •   Less than 5 years exp.  •   Consumer Technology

$94K - $148K *

Join a team that's redefining technology sourcing strategies to drive savings and innovation. Lead cross-functional collaboration, manage supplier performance, and coach a talented team to optimize te...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$100K - $120K *

Lead efforts to enhance rural healthcare by managing RHT implementation, ensuring alignment across teams, negotiating vendor services, and establishing processes for successful onboarding and support...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$160K - $200K *

Shape and drive commercial strategies to enhance revenue growth and client relationships across diverse consumer brand sectors. Collaborate with teams to ensure client satisfaction while identifying n...

United StatesRemote

Reposted 3 days ago

  •   8 - 10 years exp.  •   Media

$110K - $130K *

Advance your career by driving business development in clinical research and medical imaging. Build strategic client relationships, identify new opportunities, and contribute to innovative healthcare...

United StatesRemote

Reposted 3 weeks ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$136K - $195K *

Drive end-to-end integration governance and value realization across acquisitions. Lead cross-functional teams to ensure disciplined execution, synergy delivery, and alignment with operational excelle...

RemoteRemote

1 month ago

  •   8 - 10 years exp.  •   Energy & Utilities

$80K - $95K *

Join a team that's dedicated to enhancing client experiences through exceptional facility management. Oversee multiple locations, collaborate on strategic initiatives, and ensure a welcoming atmospher...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Legal & Accounting

$110K - $130K *

Drive impactful AI and Agentforce delivery projects, managing customer relationships and internal initiatives. Leverage your strategic planning and analytical skills to oversee project execution and f...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$100K - $230K *

Grow strategic client relationships in South Texas through solutions-driven sales. Utilize technical expertise to address complex customer needs and expand market share while fostering long-term partn...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$175K - $190K *

Lead and mentor a team of Program Managers to drive strategic data center builds, ensuring seamless execution and stakeholder alignment while navigating complex infrastructure challenges in a high-gro...

United StatesRemote

2 weeks ago

  •   11 - 15 years exp.  •   Information Technology

$130K - $170K *

Shape the future of capital projects by leading multi-discipline teams to deliver complex design packages, ensuring quality and client satisfaction across diverse sectors including healthcare and gove...

United StatesRemote

2 weeks ago

  •   8 - 10 years exp.  •   Technical Services

$90K - $130K *

Shape the future of our sales strategy by developing plans that align with business objectives and drive measurable goals, ensuring effective implementation and collaboration across regional teams to...

United StatesRemote

Reposted 2 weeks ago

  •   5 - 7 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What kinds of $100,000+ jobs are available in Iowa?question toggle

    Listings may include opportunities in healthcare, technology, finance, engineering, manufacturing, insurance, and business leadership. Roles and salary ranges vary by employer and experience.

  • Which Iowa cities have professional jobs listed?question toggle

    Explore opportunities in Des Moines, Cedar Rapids, Iowa City, Davenport, Sioux City, and other Iowa locations. Remote or hybrid openings may also be available.

  • Are all jobs on this page guaranteed to pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more, but compensation and eligibility can vary. Review each listing for its specific salary information and requirements.

  • How can I find the right high-paying job in Iowa?question toggle

    Use filters for location, job title, and other preferences, then compare responsibilities and qualifications. Keeping your resume updated and setting job alerts can help you respond to relevant openings.