Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,696

Sort By: Relevance

$157K - $298K *

Lead and scale high-performing data and analytics teams to drive business impact. Collaborate with stakeholders to refine data strategy and execute use cases, while mentoring a multi-disciplinary team...

Yesterday

  •   8 - 10 years exp.  •   Aerospace & Defense

$132K - $251K *

Shape the future of aviation by developing advanced machine learning models to enhance operational efficiency for major airlines and airports. Join a dynamic team where innovative ideas drive tangible...

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Reposted yesterday

  •   5 - 7 years exp.  •   Aerospace & Defense

$105K - $150K *

Empower construction teams by optimizing financial workflows and technology solutions. Serve as a subject matter expert in cost management, collaborating with stakeholders to enhance project cost cont...

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Yesterday

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$168K - $253K *

Lead the North America SDS R&D project portfolio, ensuring alignment with global standards. Drive project management excellence, optimize execution, and facilitate strategic transformation initiatives...

Yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$98K - $172K *

Champion patient care by providing pharmaceutical expertise, counseling, and immunizations. Engage with customers to enhance their health and well-being while ensuring compliance with regulations and...

Yesterday

  •   Less than 5 years exp.  •   Retail & Consumer Goods

$86K - $170K *

Lead the design and optimization of omnichannel customer journeys using Adobe tools. Collaborate with teams to translate strategies into actionable solutions that enhance engagement and drive results...

Yesterday

  •   Less than 5 years exp.  •   Business Services

$92K - $110K *

Transform your career with a dynamic team focused on building and optimizing scalable data solutions. Engage in cross-functional collaboration to enhance data integrity and efficiency through innovati...

Reposted yesterday

  •   Less than 5 years exp.  •   Business Services

$95K - $114K *

Join a dynamic team to lead critical application remediation efforts, collaborating with stakeholders to assess vulnerabilities and develop tailored delivery plans for successful implementation and ri...

Yesterday

  •   5 - 7 years exp.  •   Business Services

$87K - $105K *

Elevate your career by designing and deploying cutting-edge AI systems. Collaborate across the AI lifecycle, enhancing performance and integration of Large Language Models while solving real-world cha...

Yesterday

  •   Less than 5 years exp.  •   Business Services

$86K - $170K *

Join a dynamic team to design and optimize omnichannel customer journeys using Adobe tools. Collaborate with clients to enhance B2B and B2C experiences, leveraging data integration and personalization...

Yesterday

  •   Less than 5 years exp.  •   Business Services

$95K - $114K *

Join a team that's leading critical application remediation efforts, collaborating with stakeholders to assess vulnerabilities, document remediation strategies, and ensure seamless integration across...

Yesterday

  •   5 - 7 years exp.  •   Business Services

$92K - $110K *

Build scalable data architectures and manage cross-functional teams to enhance data solutions. Collaborate to optimize data collection, processing, and reporting, driving reliability and quality acros...

Reposted yesterday

  •   Less than 5 years exp.  •   Business Services

$141K - $278K *

Lead architectural efforts by integrating advanced AI technologies into enterprise systems. Collaborate cross-functionally to design, build, and secure applications on cloud platforms, ensuring scalab...

Reposted yesterday

  •   8 - 10 years exp.  •   Business Services

$141K - $278K *

Lead the integration of AI/ML models in enterprise applications. Design scalable solutions ensuring security and compliance, while collaborating with teams to align AI strategies with business goals a...

Reposted yesterday

  •   8 - 10 years exp.  •   Business Services

$74K - $107K *

Join a team that's dedicated to providing comprehensive care coordination for patients with hematological disorders. Collaborate with healthcare professionals to enhance patient outcomes through educa...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$155K - $317K *

Join a team that's transforming tax consulting by delivering innovative technology solutions. As a Senior Manager, you'll lead client engagements, drive strategy, and mentor talent, contributing to ou...

Reposted yesterday

  •   8 - 10 years exp.  •   Business Services

$95K - $115K *

Partner with us to deliver exceptional urgent care services, treating patients of all ages in a dynamic, interdisciplinary environment. Utilize your skills in a fast-paced clinic, providing quality ca...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$155K - $317K *

Partner with us to enhance tax departments through innovative technology solutions, managing client relationships while delivering strategic implementations of SAP and indirect tax engine engagements...

Reposted yesterday

  •   8 - 10 years exp.  •   Business Services

$122K - $183K *

Elevate laboratory services by collaborating with clinical leaders to enhance safety and quality initiatives. Drive strategic projects, manage budgets, and ensure compliance while fostering team devel...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$122K - $183K *

Partner with us to enhance laboratory services by collaborating with clinical leadership, managing budgets, and driving performance improvements to support clinical and safety initiatives across the o...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$122K - $183K *

Elevate laboratory operations by collaborating with clinical leaders to enhance safety and quality initiatives. Drive strategic projects, budget compliance, and performance improvements while ensuring...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$122K - $183K *

Champion laboratory services by collaborating with clinical leaders to enhance quality, efficiency, and compliance. Drive strategic initiatives, manage budgets, and foster team development to support...

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$66K - $131K *

Unlock business potential by cultivating customer relationships and driving revenue growth. Collaborate with teams to develop strategic plans, identify market opportunities, and ensure customer satisf...

Yesterday

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$108K - $130K *

Unlock potential by managing complex engineering projects with minimal supervision. Develop advanced skills while providing technical expertise and guidance to resolve intricate problems, ensuring ali...

Yesterday

  •   5 - 7 years exp.  •   Energy & Utilities

$68K - $103K *

Optimize patient care by leveraging advanced imaging techniques and collaborating with a multidisciplinary team to enhance diagnostic accuracy and improve outcomes in a dynamic healthcare environment...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.