Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,788

Sort By: Relevance

$120K - $145K *

Champion technical solutions by leading a team in delivering complex software implementations, ensuring alignment with business goals while upholding coding standards across on-prem and cloud environm...

Reposted today

  •   8 - 10 years exp.  •   Finance & Insurance

$95K - $131K *

Drive patient independence by managing Peritoneal Dialysis care, educating patients and caregivers, and collaborating with teams to ensure high-quality outcomes. This role combines clinical expertise...

Today

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Innovate AI-powered workflows by designing and optimizing multi-step solutions that address complex business challenges, leveraging large language models and orchestration frameworks to enhance operat...

Reposted today

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $180K *

Drive compliance and operational risk oversight for a Front Line Unit, ensuring adherence to policies while managing a team to identify and mitigate risks effectively. Engage in proactive risk managem...

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Lead the charge in optimizing the Safe Harbor program, ensuring timely equipment delivery and strong OEM and distributor relationships. Drive strategic planning and execution while managing a high-per...

Today

  •   5 - 7 years exp.  •   Energy & Utilities

$230K - $322K *

Grow your career with a leading ML team focused on enhancing ad retrieval systems. Drive technical direction, develop innovative models, and collaborate across teams to optimize user experience and ad...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Media

$75K - $130K *

Transform client relationships and drive sales growth by collaborating with cross-functional teams. Leverage insights and best practices to enhance client engagement and execute strategic initiatives...

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$105K - $140K *

Join us to optimize the commercial operating plan for small accounts, enhancing customer experiences and driving measurable growth through hands-on strategies and collaboration across teams...

RemoteRemote

Today

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$125K - $148K *

Empower your career by joining a dedicated post-acute care team, providing high-quality patient care in skilled nursing facilities. Enjoy autonomy, excellent support, and growth opportunities while ma...

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$110K - $130K *

Develop and maintain Python automation for derivatives trading applications, ensuring accurate trade validation across front-, middle-, and back-office workflows. Collaborate with engineers and capita...

Today

  •   5 - 7 years exp.  •   Staffing

$110K - $130K *

Transform security control assurance by engineering automated testing and monitoring solutions. Collaborate with cross-functional teams to enhance cybersecurity visibility and reduce manual efforts wh...

Today

  •   8 - 10 years exp.  •   Staffing

$110K - $130K *

Join a team that's dedicated to optimizing cybersecurity technology portfolios through data analytics, governance, and strategic insights. Collaborate across departments to enhance visibility, streaml...

Today

  •   8 - 10 years exp.  •   Staffing

$120K - $145K *

Transform enterprise communications security by leading modernization initiatives, collaborating with global teams, and designing scalable solutions that enhance protection and operational efficiency...

Today

  •   5 - 7 years exp.  •   Staffing

$88K - $105K *

Lead technology infrastructure delivery from planning to closeout, ensuring seamless coordination among construction, cabling, and field teams. Drive accountability and resolve issues to guarantee suc...

Today

  •   5 - 7 years exp.  •   Staffing

$110K - $130K *

Accelerate progress at our team by developing and executing robust testing strategies for data-intensive applications, ensuring quality and functionality throughout the software development lifecycle...

Today

  •   5 - 7 years exp.  •   Staffing

$110K - $130K *

Join a dynamic team managing mission-critical SQL Server environments, ensuring high availability and performance. Collaborate with engineering teams to optimize database operations and drive stabilit...

Today

  •   8 - 10 years exp.  •   Staffing

$83K - $115K *

Transform service delivery by leading a skilled team of engineers, ensuring operational excellence and customer satisfaction through effective coordination and relationship management. Drive continuou...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Manage enterprise data security assessments and remediation efforts, collaborating with stakeholders to enhance data protection processes and reporting metrics, ensuring compliance and operational eff...

Today

  •   8 - 10 years exp.  •   Staffing

$80K - $95K *

Join a team that's dedicated to delivering exceptional geotechnical engineering projects. Manage multiple projects, coordinate with engineers and crews, and ensure client satisfaction through effectiv...

Today

  •   5 - 7 years exp.  •   Technical Services

$110K - $130K *

Manage clinical operations for low to moderate complexity studies, ensuring timely delivery of clean data while adhering to quality and budget expectations. Collaborate with teams to meet project goal...

North Carolina, USRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$88K - $112K *

Drive the development and execution of a comprehensive enterprise risk management program, collaborating across global functions to enhance risk governance, reporting, and education while maintaining...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Business Services

$240K - $285K *

Help us shape a transformative People Operations strategy that drives organizational effectiveness and talent development. Lead initiatives from concept to execution, fostering a culture of accountabi...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Information Technology

$132K - $272K *

Elevate retail partnerships by developing integrated strategies that drive growth and innovation. Collaborate across teams to transform complex opportunities into actionable plans, enhancing commerce...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Consumer Technology

$139K - $232K *

Unlock potential by providing enterprise architecture leadership for Retail and Consumer Banking. Shape technology strategies and roadmaps across various banking capabilities, ensuring alignment with...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $150K *

Lead the charge in developing a robust security platform for exam integrity. Oversee five security domains, drive market intelligence, and ensure evidence-based performance metrics while collaborating...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.