Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,696

Sort By: Relevance

$80K - $95K *

Engage with patients as a Virtually Integrated Care RN, providing essential remote support and care coordination. Utilize advanced clinical skills to assess needs, develop care plans, and enhance pati...

RemoteRemote

Yesterday

  •   Less than 5 years exp.  •   Hospitals & Medical Centers

$110K - $130K *

Optimize the Innovation portfolio by leading high-impact projects, collaborating with senior leaders, and driving strategic initiatives. Your role will ensure seamless operations and foster growth in...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Healthcare

$160K - $200K *

Drive the growth of Data Science and AI initiatives across diverse sectors, focusing on strategic industries. Lead business development, advisory roles, and solution creation to enhance client engagem...

United StatesRemote

Yesterday

  •   11 - 15 years exp.  •   Information Technology

$80K - $95K *

Transform public sector compliance reporting by ensuring accuracy, timeliness, and adherence to contractual obligations. Collaborate across teams to mitigate risks and enhance operational efficiency t...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Information Technology

$100K - $120K *

Innovate patient care by delivering expert pharmaceutical services in home infusion therapy. Collaborate with healthcare teams to ensure optimal drug therapy outcomes while adhering to regulatory stan...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$90K - $140K *

Join a dynamic team to lead complex data management projects, blending Agile methodologies with technical expertise. Drive collaboration across healthcare analytics, ensuring successful delivery and s...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Legal & Accounting

$150K - $180K *

Lead a high-performing sales team to drive new logo acquisition and revenue growth in enterprise software. Develop strategies, foster collaboration, and engage executive customers to expand market sha...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Enterprise Technology

$110K - $130K *

Lead the transformation of healthcare IT by managing ServiceNow projects, enhancing workflows, and ensuring seamless integration. Collaborate with cross-functional teams to deliver innovative solution...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Healthcare

$120K - $175K *

Join a team that's dedicated to managing complex professional liability claims, focusing on legal malpractice. Leverage your expertise to evaluate coverage, negotiate outcomes, and ensure timely reser...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$83K - $104K *

Join a team that's dedicated to empowering patients through effective speech therapy. As a Speech Language Pathologist, you'll design and implement personalized rehab plans, enhancing communication an...

Yesterday

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Transform operational excellence by leading technical initiatives to optimize manufacturing processes, enhance equipment reliability, and drive continuous improvement in a dynamic production environme...

Yesterday

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$126K - $236K *

Lead the charge in consumer engagement and growth strategy, driving awareness and deepening user connections across channels. Collaborate cross-functionally to optimize campaigns that inspire action a...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Media

$135K - $175K *

Drive the integration of AI tools into a secure cloud platform for capital markets, ensuring compliance and security while collaborating with top law firms and engineering teams to enhance document wo...

RemoteRemote

Yesterday

  •   5 - 7 years exp.  •   Enterprise Technology

$160K - $190K *

Drive transformation initiatives by leading cross-functional teams to enhance client onboarding and service operations. Own the end-to-end process from strategy to execution, ensuring measurable outco...

Yesterday

  •   5 - 7 years exp.  •   Finance & Insurance

$90K - $110K *

Join a team that's driving enterprise growth by building relationships and closing new business. This proactive sales role focuses on acquiring customers for innovative workforce development solutions...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Education, Government & Non-Profit

$80K - $95K *

Provide leadership for dynamic distribution operations, ensuring safety, efficiency, and quality in the movement and storage of materials. Collaborate across functions to drive continuous improvement...

Reposted yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Lead the charge in overseeing a large distribution operation, ensuring safe and efficient movement of materials. Drive operational excellence, safety standards, and continuous improvement while managi...

Reposted yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$275K - $340K *

Drive growth by leading sales and customer success teams, refining strategies, and optimizing processes. Shape the commercial landscape while mentoring talent and ensuring high-value customer relation...

United StatesRemote

Yesterday

  •   5 - 7 years exp.  •   Media

$199K - $269K *

Shape patient affordability strategies by leading a dynamic team focused on co-pay programs and innovative solutions. Collaborate cross-functionally to enhance operations, optimize performance, and dr...

United StatesRemote

Reposted yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$191K - $258K *

Shape the future of global safety by leading the development and submission of periodic aggregate safety reports. Drive compliance and collaboration across teams while managing a diverse global team t...

United StatesRemote

Yesterday

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$143K - $169K *

Drive customer-centric strategies by analyzing data, optimizing journeys, and collaborating across teams to enhance the overall customer experience. Lead initiatives that align with organizational goa...

United StatesRemote

Yesterday

  •   8 - 10 years exp.  •   Consumer Technology

$182K - $266K *

Optimize operational performance by leading Continuous Improvement initiatives across manufacturing sites. Collaborate with leaders to implement strategic plans, enhance quality systems, and drive org...

Yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$182K - $266K *

Join a team that's driving operational excellence through Continuous Improvement initiatives. Collaborate across functions to enhance manufacturing performance, implement strategic plans, and build su...

Yesterday

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$75K - $120K *

Advance your career by developing and supporting diverse applications, balancing project delivery with troubleshooting. Collaborate with teams to enhance systems and ensure reliable performance across...

Reposted yesterday

  •   Less than 5 years exp.  •   Media

$171K - $274K *

Manage complex commercial real estate transactions while advising executives. Leverage legal expertise in mortgage loans to influence strategic initiatives and advance compliance, fostering innovation...

Reposted yesterday

  •   8 - 10 years exp.  •   Media

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.