Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Average Salary: $114,696
IT INFRASTRUCTURE ARCHITECT - 40011477
$92K - $153K *
Engineer cutting-edge enterprise IT infrastructure solutions. Lead strategic architecture planning and governance, ensuring scalability and security across networks, servers, and cloud platforms while...
Reposted today
$120K - $145K *
Shape the future of life science projects by leading multi-discipline teams, ensuring project delivery excellence, and fostering client relationships. Drive business growth while mentoring staff and m...
Today
AI Workforce - Endpoint Technical Lead (Delivery Focused)
$175K - $200K *
Transform enterprise endpoint solutions by leading architecture and delivery across Microsoft technologies. Drive operational excellence and ensure compliance while mentoring teams and collaborating w...
Today
Staff, Product Manager - Identity
$155K - $228K *
Join a team that's shaping the future of identity products, delivering secure, developer-first experiences. Collaborate with leadership to build innovative solutions that empower customers and enhance...
Today
Account Executive - North America New Logo
$140K - $220K *
Join a dynamic team focused on driving new business growth through strategic sales initiatives. Engage with key decision-makers, execute impactful presentations, and leverage multi-channel outreach to...
Today
Regulatory Affairs Director (Remote - United States)
$211K - $290K *
Champion global regulatory strategies to drive product approvals and market access for innovative dental solutions. Collaborate with cross-functional teams to navigate complex regulatory landscapes an...
Today
$95K - $115K *
Engage in strategic marketing management for Vascular product lines, leading a high-performing team to enhance market presence and drive sales growth. Your expertise in market dynamics will guide effe...
Reposted today
Human Resources Business Partner
$88K - $105K *
Join a dynamic team driving HR excellence by partnering with leadership to enhance talent, culture, and performance. Utilize data-driven insights and HR expertise to align organizational priorities an...
Reposted today
Affiliate Marketing Manager - US, Remote
$85K - $144K *
Take ownership of the North America affiliate channel by driving strategy, measuring performance, and fostering growth while leading a team and optimizing partnerships for maximum profitability...
Reposted today
Account Success Manager - Carolinas
$85K - $95K *
Optimize patient access and support healthcare providers in referrals by fostering strong relationships, enhancing resource utilization, and ensuring effective onboarding throughout your assigned terr...
Reposted today
Senior Staff Frontend Engineer
$150K - $180K *
Join us to architect a unified web platform that enhances user experience across multiple services. Lead front-end development, optimize performance, and mentor engineers while ensuring seamless integ...
Today
$108K - $130K *
Optimize procurement and supply chain activities for nuclear project delivery. Integrate procurement into planning and execution phases, ensuring compliance, cost-effectiveness, and supplier performan...
Reposted today
$80K - $95K *
Evaluate and enhance federal audit readiness and compliance. Collaborate cross-functionally to strengthen controls and mitigate compliance risks, while supporting corrective actions and fostering sust...
Reposted today
Director, Subcontract Management
$120K - $145K *
Lead the charge in federal subcontract management, ensuring compliance and effective execution across projects. Develop processes and build a strong team to foster growth in a dynamic federal services...
Reposted today
$110K - $130K *
Manage the full sales cycle to open new mid-market and enterprise accounts, develop cross-sell opportunities, and grow customer relationships through high-value cybersecurity services, ensuring commer...
Reposted today
Senior Mechanical Estimating Engineer (Life Sciences)
$95K - $115K *
Lead the future of mechanical and electrical engineering by managing complex projects, developing budgetary estimates, and mentoring less experienced staff while ensuring quality and compliance with s...
Reposted today
$90K - $110K *
Empower strategic growth by managing key accounts across diverse sectors. Drive revenue, enhance client relationships, and deliver integrated solutions while collaborating with global teams to ensure...
Reposted today
$80K - $95K *
Elevate project outcomes by leading moderately complex construction initiatives, ensuring adherence to safety standards, timelines, and budget management while fostering collaboration among stakeholde...
Reposted today
Customer Care Center Trainer - Remote U.S/CAN
$72K - $90K *
Empower our contact center teams by developing and delivering impactful training programs. Drive performance improvement and enhance patient experiences through effective coaching and collaboration wi...
Reposted today
Sr QLTY & RELIABILITY ENGINEER
$95K - $115K *
Lead quality improvement initiatives and ensure compliance by driving root cause analysis and cross-functional collaboration to enhance production integrity and customer satisfaction, while leveraging...
Reposted today
Fleet Maintenance Superintendent
$78K - $125K *
Champion the City’s Fleet Maintenance Garage by overseeing operations, managing budgets, and leading a skilled team to ensure optimal performance of all vehicles and equipment while adhering to safety...
Today
$74K - $95K *
Advance operational excellence by leading nationwide store audits, ensuring compliance, identifying risks, and driving continuous improvement in collaboration with cross-functional teams to enhance pe...
Reposted today
$120K - $145K *
Elevate your career by leading mechanical design for complex power generation projects. Drive technical excellence and mentor a team while managing project lifecycles from design to commissioning in a...
Today
Senior Director of Purchasing & Global Sourcing
$150K - $180K *
Lead strategic purchasing and global sourcing initiatives, driving supplier partnerships and optimizing costs while ensuring supply chain resilience and operational alignment across manufacturing oper...
Reposted today
ASIC Design Verification Engineer I (Full Time) - United States
$94K - $140K *
Contribute to the development of cutting-edge ASIC solutions by collaborating with cross-functional teams to ensure optimal performance and seamless integration of hardware platforms through rigorous...
Today
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.