Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Average Salary: $114,677
Medical Science Liaison /Senior Medical Science Liaison - Specialty - Northeast Region
$162K - $203K *
Transform your career by engaging with key opinion leaders in Urology and Women's Health. Leverage your scientific expertise to drive medical strategies and foster relationships that enhance product u...
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Senior Manager, Payment Integrity - Vended Audit Programs
$107K - $199K *
Optimize cost recovery initiatives by managing vendor partnerships and streamlining processes. Collaborate with health plans to achieve budget targets and present actionable insights to senior managem...
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$110K - $130K *
Lead the charge in managing complex ITS and traffic management projects, overseeing planning, design, and deployment. Collaborate with multidisciplinary teams to enhance transportation systems and imp...
Today
$100K - $160K *
Unlock potential by leading our channel strategy for System Integrators and Mechatronics across the Americas. Drive sales growth, enhance partner relationships, and implement successful initiatives to...
Reposted today
Manager, Health Informatics (Midwest)
$152K - $253K *
Transform healthcare delivery by leveraging health information technology to enhance patient care and operational efficiency. Collaborate with health systems and cross-functional teams to align techno...
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Lead Consultant CDH Implementation
$105K - $149K *
Transform complex Consumer-Directed Health implementations for major employers. Lead strategy, execution, and client engagement while serving as a subject-matter expert to ensure operational excellenc...
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$80K - $95K *
Grow your career with a dynamic team as you lead operations in a healthcare facility, focusing on patient care, team development, and financial management while fostering a culture of continuous impro...
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Strategic Business Developer 5
$120K - $145K *
Shape the future of avionics sales by leading business development efforts, engaging military and commercial aerospace customers, and driving strategic growth in the Americas through innovative test s...
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Director Manufacturing & Industrial Engineering
$130K - $155K *
Champion innovative manufacturing processes by leading engineering teams to enhance efficiency, safety, and quality across multiple sites. Drive continuous improvement initiatives and collaborate with...
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Director, Technical Product Management
$150K - $180K *
Pioneer the strategy and execution of data platforms and AI products, leading cross-functional teams to enhance commercial life sciences solutions while driving revenue growth and product adoption in...
Reposted today
$88K - $105K *
Shape Cencosud's external communications strategy, fostering relationships with media and stakeholders. Drive community engagement initiatives, manage reputational risks, and ensure alignment with cor...
Reposted today
Product Client Success Manager (First Party Casualty)
$78K - $120K *
Transform claims operations as you empower clients by driving adoption of innovative solutions, optimizing processes, and enhancing business outcomes in the First Party Casualty landscape across vario...
Reposted today
Marketing Manager- Duke Health Lake Norman
$80K - $95K *
Grow your career with a dynamic marketing role that drives strategic initiatives, enhances brand awareness, and fosters partnerships to support healthcare growth and patient engagement in the Lake Nor...
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$110K - $130K *
Reimagine patient care by delivering expert pharmacy services and consultations. Lead a collaborative team, ensuring medication safety and compliance while advancing your career through growth opportu...
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$110K - $130K *
Empower patients by delivering expert pharmacy services, educating on medications, and ensuring safety through compliance. Collaborate with a dedicated team to enhance healthcare outcomes and foster p...
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$88K - $105K *
Join a team that's driving innovation in project management for our Merchandising division. You'll oversee a diverse portfolio, ensuring timely execution and alignment with strategic goals to enhance...
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$137K - $315K *
Unlock your potential by designing and implementing key components of an advanced inference platform, enhancing execution efficiency for large language models in diverse environments. Collaborate with...
Reposted today
HDNU Projects Supplier Engagement Leader - Supplier Development
$125K - $208K *
Transform supplier engagement strategies to enhance performance and scalability. Collaborate with cross-functional teams to drive initiatives and improvements within the supply chain, ensuring alignme...
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$100K - $120K *
Lead the charge in overseeing financial functions across multiple divisions, ensuring accurate reporting and operational support. Drive budgeting, forecasting, and process improvements to enhance prof...
Reposted today
$81K - $110K *
Lead the transformation of patient care by enhancing utilization review processes, ensuring quality documentation, and collaborating with healthcare teams to optimize clinical outcomes and financial p...
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Business Process Improvement & Internal Controls Specialist Department of War (DOW)
$61K - $101K *
Unlock potential by joining a dynamic team focused on financial management, internal controls, and fraud risk. Collaborate with federal clients to enhance processes and drive measurable outcomes in au...
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$80K - $95K *
Innovate customer engagement by executing targeted ABM campaigns that drive site expansion within Enterprise and Mid-Market accounts, ensuring timely outreach and pipeline growth through multi-channel...
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Pharmacist - Full-time Floater
$110K - $130K *
Lead the charge in providing exceptional pharmacy services, motivating staff, and ensuring operational excellence across multiple locations. Empower teams to enhance patient care while maintaining hig...
Reposted today
$95K - $115K *
Transform financial leadership in a dynamic 24/7 manufacturing environment. Drive accurate reporting, cost controls, and strategic analysis to enhance productivity and profitability while partnering w...
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$70K - $100K *
Unlock potential by driving business growth through consultative sales, building relationships, and delivering tailored wildlife solutions to residential and commercial clients while ensuring exceptio...
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What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.