Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,677

Sort By: Relevance

$80K - $95K *

Drive innovation in healthcare technology management by serving as a key advisor in biomedical engineering, overseeing medical technology infrastructure, and ensuring seamless integration of clinical...

Today

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$150K - $180K *

Drive transformative AI initiatives across departments by leading a strategic team in designing scalable, agentic workflows that enhance decision-making and efficiency, ensuring measurable business ou...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Healthcare

$222K - $278K *

Empower businesses by eliminating supply chain blind spots. Drive adoption of our innovative Tracking Label product, collaborating with Enterprise teams to enhance shipment visibility and security acr...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$160K - $200K *

Drive the evolution of Sales Operations by designing and optimizing processes, governance, and technology to enhance execution and productivity across the organization, ensuring alignment with strateg...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$100K - $155K *

Empower targeted marketing initiatives that drive engagement and revenue growth. Collaborate with Sales and Product teams to create personalized strategies, leveraging insights and AI tools to enhance...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$95K - $123K *

Lead inventory control and quality initiatives, ensuring compliance and operational excellence across multiple facilities. Collaborate with cross-functional teams to drive performance, mitigate risks...

Today

  •   5 - 7 years exp.  •   Transportation

$90K - $110K *

Unlock potential by overseeing clinical trials, ensuring compliance with protocols and regulations. Collaborate with investigators and coordinators to protect participant rights and verify data integr...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Healthcare

$85K - $95K *

Accelerate progress at our Third Party Management vertical by engaging in prospecting and sales processes. Collaborate with leadership to define strategies, enrich CRM, and generate opportunities that...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$85K - $100K *

Join a team that's focused on driving financial accuracy while managing month-end closes, reconciliations, and cost accounting. Contribute to board-level reporting in a dynamic PE-backed SaaS environm...

United StatesRemote

Reposted today

  •   5 - 7 years exp.  •   Healthcare

$95K - $115K *

Join a dynamic team to lead proposal development for transportation projects, driving win strategies and fostering collaboration across multidisciplinary teams to deliver compelling, client-focused su...

Today

  •   5 - 7 years exp.  •   Real Estate & Construction

$75K - $90K *

Drive operational excellence by leading a dynamic team in a fast-paced environment, ensuring top-notch service and product quality while achieving sales growth and fostering a positive workplace cultu...

Today

  •   Less than 5 years exp.  •   Food & Beverages

$75K - $90K *

Drive your career with a dynamic leadership role overseeing operations, enhancing customer experience, and maximizing sales growth in a fast-paced restaurant environment. Lead a team to deliver except...

Today

  •   Less than 5 years exp.  •   Food & Beverages

$75K - $90K *

Lead the charge in driving operational excellence and sales growth in a dynamic restaurant environment, ensuring top-notch customer service and team performance while managing daily operations effecti...

Today

  •   Less than 5 years exp.  •   Food & Beverages

$110K - $130K *

Elevate analytics capabilities by designing and implementing robust ETL processes, data solutions, and dashboards. Lead projects, mentor developers, and drive data-driven decision-making across teams...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Energy & Utilities

$100K - $120K *

Optimize telecom financial governance by managing contracts, analyzing costs, and ensuring compliance across enterprise services. Collaborate with cross-functional teams to enhance operational efficie...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$110K - $130K *

Empower your career by leading manufacturing and industrial engineering teams to design and implement efficient production systems. Collaborate across functions to drive innovation, optimize processes...

Today

  •   5 - 7 years exp.  •   Energy & Utilities

$81K - $96K *

Join a dynamic team to oversee property operations, enhance resident satisfaction, and drive revenue growth. Lead and mentor staff while ensuring compliance with policies and maintaining a market-read...

Today

  •   Less than 5 years exp.  •   Real Estate & Construction

$143K - $208K *

Join a dynamic team as you lead enterprise-wide manufacturing strategy, ensuring performance and scalability across multiple facilities while driving cross-functional collaboration and continuous impr...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$95K - $115K *

Partner with us to lead financial management in a dynamic 24/7 manufacturing environment. Drive cost controls, budgeting, and financial analysis while collaborating with cross-functional teams to enha...

Today

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$68K - $97K *

Unlock potential by delivering innovative designs that elevate brand identity. Collaborate on strategic campaigns, mentor junior designers, and lead complex projects from concept to execution, all whi...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$194K - $361K *

Lead the development of innovative NovaOS capabilities, ensuring alignment with business goals and driving continuous improvement through collaboration across cross-functional teams. Deliver measurabl...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$175K - $200K *

Pioneer enterprise endpoint solutions by leading architecture and delivery across Microsoft technologies. Drive transformation programs, ensuring operational excellence and adherence to security stand...

Today

  •   5 - 7 years exp.  •   Business Services

$100K - $120K *

Elevate your career by resolving complex commercial property losses, managing national accounts, and providing expert insights. Collaborate with diverse stakeholders while ensuring compliance and main...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$175K - $200K *

Shape the future of enterprise endpoint solutions by leading architecture and delivery across Microsoft technologies. Drive operational excellence and ensure compliance while mentoring teams and manag...

Today

  •   5 - 7 years exp.  •   Business Services

$133K - $184K *

Join a team that's enhancing threat detection and response capabilities. As a hands-on technical leader, you'll drive security initiatives across cloud, infrastructure, and identity platforms, while m...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.