Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,677

Sort By: Relevance

$115K - $140K *

Drive operational excellence in commercial readiness and support cross-functional teams to ensure effective execution of launch strategies and operational priorities in a dynamic biotech environment...

United StatesRemote

Reposted today

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$225K - $275K *

Optimize quality assurance processes to ensure compliance with regulatory standards and drive improvements across all operations. Lead a talented team to establish and maintain an effective Quality Ma...

United StatesRemote

Reposted today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Join a team that's driving growth by acquiring new prospects and expanding existing accounts in the Fintech sector. Leverage your strategic selling skills to navigate complex sales cycles and achieve...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Finance & Insurance

$92K - $139K *

Elevate customer success by managing a portfolio of enterprise accounts, ensuring optimal software utilization, and fostering strong relationships. Collaborate with clients to solve complex challenges...

RemoteRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$83K - $138K *

Lead the strategy and performance management for our mobile app and loyalty experience, driving athlete engagement and revenue growth through cross-functional collaboration and data-driven insights. O...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$95K - $115K *

Join a team that's redefining product marketing by leading impactful go-to-market strategies, enabling sales teams, and shaping customer insights to drive success in a fast-paced B2B SaaS environment...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Information Technology

$132K - $207K *

Elevate your career by driving growth in the mortgage industry, partnering with top lenders to enhance FICO's analytics solutions. Lead strategic initiatives, foster client relationships, and deliver...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$200K - $225K *

Transform marketing strategies to drive growth and engagement across public and private sectors. Lead integrated marketing efforts, brand positioning, and customer marketing services while leveraging...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Education, Government & Non-Profit

$157K - $256K *

Shape strategic pricing and channel strategies for innovative therapies, ensuring patient access and affordability. Lead cross-functional initiatives, optimize distribution models, and drive market in...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Champion the evolution of enterprise infrastructure by leading zOS system programming efforts, ensuring optimal performance and reliability through troubleshooting, automation, and collaboration with...

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$120K - $145K *

Optimize data pipelines and integrate AI models to enhance document processing workflows. Collaborate with cross-functional teams to ensure data quality and scalability while transforming unstructured...

Today

  •   5 - 7 years exp.  •   Enterprise Technology

$95K - $115K *

Join our team to enhance software solutions by documenting requirements, facilitating design discussions, and integrating new features. Your expertise will ensure system stability and quality while su...

Today

  •   Less than 5 years exp.  •   Information Technology

$120K - $182K *

Accelerate growth by driving new software sales, building client relationships, and tailoring solutions to meet unique business needs. Collaborate with cross-functional teams to ensure a seamless cust...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Enterprise Technology

$140K - $160K *

Join us in leading electrical engineering for industrial EPC projects. Drive technical excellence, mentor teams, and ensure compliance with industry standards while enhancing project delivery and effi...

Today

  •   5 - 7 years exp.  •   Staffing

$86K - $143K *

Partner with us to enhance client relationships and drive advertising success. In this role, you'll manage mid-tier accounts, support complex campaigns, and collaborate with cross-functional teams to...

Today

  •   Less than 5 years exp.  •   Real Estate & Construction

$86K - $143K *

Champion client relationships by managing day-to-day communications and supporting advertising programs. Collaborate with cross-functional teams to ensure alignment with client objectives and deliver...

Mooresville, NCRemote

Today

  •   Less than 5 years exp.  •   Real Estate & Construction

$93K - $232K *

Transform clinical trial delivery by leading multi-regional studies and fostering client relationships. Drive operational excellence while mentoring cross-functional teams in advancing therapies withi...

Reposted today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Unlock potential by driving research in prediction markets, developing alpha signals, and collaborating through the entire model implementation process. Guide projects from data analysis to live tradi...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Finance & Insurance

$85K - $105K *

Optimize regulatory compliance processes for a multi-state transportation network. Collaborate cross-functionally to ensure operational readiness and manage ongoing compliance across diverse markets...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Healthcare

$100K - $120K *

Empower customer success by cultivating strategic partnerships, driving retention, and executing account plans. Collaborate with internal teams to deliver tailored solutions, ensuring customer satisfa...

RemoteRemote

Today

  •   5 - 7 years exp.  •   Consumer Technology

$168K - $210K *

Transform pricing strategies by leading cross-functional teams to enhance decision-making and model deployment. Drive the evolution of pricing platforms, integrating advanced AI to streamline workflow...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Enterprise Technology

$133K - $156K *

Optimize client engagement and revenue growth by leading operations that integrate customer service and sales. Drive strategic execution and operational excellence across multi-channel environments to...

Today

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Shape the future of financial strategy by partnering with senior leaders to drive smarter investments, optimize spending, and enhance corporate financial planning. Take ownership of budgeting, forecas...

Today

  •   5 - 7 years exp.  •   Retail & Consumer Goods

$120K - $150K *

Elevate your career by driving enterprise sales for innovative solutions. Engage with multinational accounts, build strategic relationships, and lead complex negotiations to unlock growth opportunitie...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$80K - $95K *

Drive your career forward by managing plumbing projects in commercial construction. Oversee planning, execution, and coordination with teams and subcontractors to ensure successful project delivery wh...

Today

  •   Less than 5 years exp.  •   Real Estate & Construction

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.