Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,788

Sort By: Relevance

$235K - $350K *

Transform the future of cyber defense by architecting cutting-edge AI systems that autonomously protect against real-world threats. Lead technical direction, mentor teams, and drive innovation from re...

United StatesRemote

Today

  •   11 - 15 years exp.  •   Information Technology

$100K - $145K *

Elevate your career by managing Kubernetes clusters across diverse environments. Collaborate with senior engineers to automate processes, troubleshoot issues, and enhance platform performance while de...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Information Technology

$80K - $95K *

Reimagine patient care as an outpatient orthopedic Physical Therapist, delivering individualized treatment in a collaborative environment that fosters growth and mentorship while focusing on diverse p...

Today

  •   Less than 5 years exp.  •   Healthcare

$85K - $105K *

Join a dynamic team to drive rental growth in dewatering solutions. Leverage your sales expertise to expand customer relationships and achieve revenue targets across diverse markets while collaboratin...

Today

  •   5 - 7 years exp.  •   Energy & Utilities

$130K - $160K *

Lead a team of Application Engineers focused on capital solutions, ensuring opportunity evaluations are thorough, project execution effective, and innovative technologies developed for global and Nort...

Reposted today

  •   5 - 7 years exp.  •   Energy & Utilities

$110K - $130K *

Collaborate with HR and legal teams to provide comprehensive employment law support, drafting and negotiating contracts while ensuring compliance with regulations. Balance legal risks with business ob...

United StatesRemote

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  •   5 - 7 years exp.  •   Real Estate & Construction

$97K - $144K *

Lead the charge in developing scalable web applications using .NET/C# and React. Collaborate on microservices, REST APIs, and CI/CD pipelines while mentoring peers and ensuring seamless communication...

Today

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Transform the nuclear supply-chain framework by leading cross-functional teams to enhance supplier readiness and compliance, ensuring operational excellence for global projects in a regulated environm...

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Champion the development of a nuclear supply-chain framework, leading cross-functional teams to enhance supplier readiness and compliance while driving project delivery and operational excellence for...

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$174K - $234K *

Shape the future of Hematology analytics by leading strategic insights and performance initiatives. Collaborate with cross-functional teams to enhance field execution and drive commercial success thro...

United StatesRemote

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  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$133K - $173K *

Drive compliance excellence by managing global monitoring programs and investigations. Collaborate with stakeholders to enhance compliance infrastructure and ensure adherence to regulations, while lea...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$105K - $140K *

Lead the charge in monitoring clinical study sites, ensuring data integrity and patient safety while collaborating with diverse teams to enhance study delivery and compliance with regulatory standards...

United StatesRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$121K - $206K *

Lead the charge in architecting and delivering Microsoft Azure and 365 solutions for SMBs. Oversee cloud migrations, security implementations, and project management while fostering strong partner rel...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Business Services

$97K - $165K *

Shape the future of cloud solutions by leading technical relationships, validating AWS architectures, and driving presales strategies. Empower teams through mentorship while ensuring secure, scalable...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Business Services

$74K - $124K *

Elevate compensation strategies by transforming complex data into actionable insights. Collaborate with stakeholders to manage compensation programs, analyze trends, and recommend solutions that ensur...

United StatesRemote

Today

  •   5 - 7 years exp.  •   Finance & Insurance

$485K *

Transform franchise growth in the Extended Stay sector by leading strategic initiatives, managing a team of Regional Vice Presidents, and building key relationships to enhance development opportunitie...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Hospitality & Recreation

$95K - $115K *

Drive excellence in pharmacy operations by ensuring accurate medication dispensing, compliance with regulations, and effective team leadership. Collaborate with healthcare professionals to enhance pat...

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$162K - $207K *

Lead the charge in implementing and optimizing SAP Vistex solutions, translating business strategies into technical architecture while managing cross-functional teams and project deliverables for enha...

United StatesRemote

Today

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Shape the future of water and wastewater planning by leading project teams, enhancing client relationships, and driving operational excellence in a dynamic environment focused on growth and innovation...

Today

  •   11 - 15 years exp.  •   Business Services

$129K - $185K *

Unlock potential by leading the Customer Identity & Access Management function, overseeing CIAM platform operations, and driving identity strategy across global digital ecosystems while collaborating...

United StatesRemote

Today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$112K - $154K *

Optimize the design and evaluation of complex electromechanical systems. Lead projects as the Responsible Engineer, ensuring technical excellence and innovation in motion control and electrical engine...

Today

  •   5 - 7 years exp.  •   Aerospace & Defense

$120K - $180K *

Shape your career by developing strategic sales plans, conducting impactful presentations, and building strong relationships to achieve sales goals in the pharmaceutical sector while adhering to ethic...

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  •   11 - 15 years exp.  •   Pharmaceuticals & Biotech

$100K - $162K *

Unlock potential by developing effective strategies and relationships to drive sales growth in the territory, ensuring compliance with regulations and high levels of customer engagement through effect...

RemoteRemote

Reposted today

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$72K - $108K *

Engage with targeted customers to drive sales growth through strategic planning, effective presentations, and relationship building while adhering to ethical practices and achieving quarterly goals in...

RemoteRemote

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  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$72K - $108K *

Join a team that's dedicated to driving sales success through strategic planning and relationship building. You'll engage with customers, achieve sales goals, and enhance product awareness while foste...

RemoteRemote

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  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.