Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Average Salary: $114,788
RN Clinical Nurse II- Acute Neurosurgery and ENT Day Shift
$71K - $100K *
Join a team that's dedicated to providing exceptional care for complex surgical patients. You'll enhance your clinical skills while collaborating with a multidisciplinary team in a fast-paced acute ca...
1 week ago
RN Clinical Nurse II - Burn Intensive Care Unit
$71K - $100K *
Join a team that's dedicated to providing exceptional nursing care in a specialized burn unit. Collaborate with interdisciplinary teams to enhance patient recovery through comprehensive assessments, e...
1 week ago
RN Command Center - Advance Care at Home Command Center
$71K - $100K *
Innovate in patient care by providing high-quality nursing support within the Advanced Care at Home model, utilizing critical thinking and collaboration to enhance patient outcomes across diverse popu...
1 week ago
Reproductive Psychiatrist (MD/DO) - UNC School of Medicine
$180K - $220K *
Lead the charge in providing specialized outpatient care for women's mood disorders, including perinatal and perimenopausal conditions. Collaborate with multidisciplinary teams and contribute to clini...
1 week ago
Contracts Officer, UNC Clinical Research Partners
$80K - $95K *
Unlock potential by leading contract negotiations for clinical research, ensuring compliance and efficiency in agreements with industry sponsors. Collaborate with diverse teams to enhance processes an...
1 week ago
Urology Physician (MD/DO) - UNC Health Rex (Raleigh/Smithfield)
$250K - $300K *
Unlock potential by joining a dynamic urology practice, collaborating with a team of skilled physicians. Enjoy a balanced schedule, advanced technology, and opportunities for academic involvement in a...
1 week ago
Rheumatology Physician (MD/DO) - Faculty - Univ of North Carolina at Chapel Hill
$210K - $250K *
Lead the charge in delivering exceptional patient care and education while mentoring fellows and residents in a collaborative academic environment focused on rheumatology and internal medicine...
1 week ago
$90K - $115K *
Engage in network operations and support within a hybrid environment, enhancing infrastructure stability and performance. Collaborate with teams to troubleshoot and maintain systems, while expanding y...
1 week ago
Compliance Testing Manager (US)
$91K - $145K *
Champion AI governance by developing frameworks and standards for compliance monitoring. Oversee AI-related risks and enhance technology solutions to ensure alignment with regulatory expectations and...
1 week ago
Compliance Testing Manager (US)
$91K - $136K *
Pioneer a transformative compliance program by overseeing independent testing, managing operations, and collaborating with stakeholders to enhance compliance strategies in a dynamic environment. Your...
1 week ago
$80K - $95K *
Transform construction operations by leading teams to deliver high-quality projects, enhance customer satisfaction, and drive continuous improvement in a fast-paced environment. Focus on optimizing pr...
1 week ago
$90K - $100K *
Join a team that's dedicated to driving client success through strategic marketing engagement. You'll manage client relationships, enhance platform adoption, and collaborate cross-functionally to achi...
1 week ago
$80K - $95K *
Lead talent acquisition efforts by collaborating with business leaders to identify and attract top candidates. Develop innovative recruiting strategies and ensure a positive candidate experience while...
1 week ago
Senior Manager, Cybersecurity Risk Management
$120K - $150K *
Transform cybersecurity risk management by providing independent oversight and insights across key domains. Collaborate with stakeholders to assess risks, enhance controls, and ensure compliance with...
1 week ago
FSP Associate Manager, Safety Data and Systems - Pharmacovigilance
$110K - $130K *
Transform safety data management by leading AI/ML initiatives, ensuring compliance with regulatory standards, and driving efficiencies in pharmacovigilance processes through innovative technology solu...
Reposted 1 week ago
$170K - $195K *
Elevate revenue growth by building strong relationships with law firms and corporations. Drive new business development through consultative sales, leveraging industry insights and collaboration with...
1 week ago
FSP - Sr Regulatory Program Manager - client dedicated
$120K - $145K *
Join a team that's redefining regulatory excellence by leading global strategies for product development and post-marketing. Drive cross-functional collaboration and ensure timely execution of regulat...
Reposted 1 week ago
Bus Operations Training Manager
$100K - $120K *
Lead the charge in developing and managing bus operations training programs, ensuring effective delivery and compliance. Collaborate with internal teams to enhance training quality and support safe, p...
1 week ago
$110K - $180K *
Elevate your career by leading the design and development of dealer-facing applications. Drive secure, scalable platforms while mentoring engineers and collaborating with cross-functional teams to enh...
1 week ago
Regional Director Resident Care RN
$102K - $158K *
Partner with us to lead clinical excellence across multiple communities, ensuring safe, evidence-based resident care. Drive quality, compliance, and performance improvement while mentoring community l...
1 week ago
Optometrist - (Full-Time/Flexible Schedule)
$162K - $208K *
Join our team as an Optometrist, providing essential eye care services in nursing homes and assisted living facilities. Enjoy flexible scheduling, competitive pay, and the support of a dedicated admin...
1 week ago
Director, Private Infrastructure
$149K - $211K *
Lead the charge in managing private infrastructure investments, overseeing portfolio analysis, and driving deal sourcing and due diligence. Collaborate with cross-functional teams to enhance asset per...
Reposted 1 week ago
Associate Director for Leadership and Character in the Law School
$80K - $95K *
Engage with JD students to foster leadership and character development through mentorship, workshops, and collaborative programming. Assess and enhance initiatives while supporting a diverse and inclu...
1 week ago
Principal Contracts Strategist (Pre-Award)
$125K - $150K *
Lead complex contract strategy and execution, enhancing scalable systems to support sales and growth. Collaborate across teams to align contracts with business needs while addressing immediate challen...
1 week ago
Area Vice President Clinical Delivery Service Line Administration- Children's Service Line
$90K - $144K *
Lead the charge in enhancing operational excellence and patient care by overseeing clinical services, driving strategic initiatives, and fostering high-performing teams within a dynamic healthcare env...
Reposted 1 week ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.