Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Average Salary: $114,816
Optometrist - Doctor of Optometry (Employee)
$200K *
Unlock potential by delivering exceptional eye care through comprehensive exams and personalized treatment plans in a dynamic, patient-centered environment. Embrace innovation and excellence while rep...
1 week ago
RN Clinical Nurse II - Medicine Progressive Care Unit
$71K - $100K *
Advance patient care by delivering expert nursing services in a dynamic, multidisciplinary environment. Collaborate with healthcare teams to ensure optimal outcomes for a diverse patient population, i...
1 week ago
$91K - $179K *
Manage manufacturing transformation initiatives by aligning shop-floor operations with digital solutions, enhancing production efficiency, quality, and traceability across the value chain while collab...
1 week ago
RN Clinical Nurse II - Medical/Surgical Department
$71K - $100K *
Transform patient care by delivering competent clinical nursing in a dynamic medical-surgical unit. Collaborate with a dedicated team to enhance patient outcomes and ensure high-quality care in a supp...
1 week ago
IT Auditor Sr - Audit Services
$80K - $115K *
Join a team that's dedicated to enhancing IT governance and security. Lead audits and advisory engagements to identify risks, assess controls, and provide actionable recommendations, ensuring complian...
1 week ago
RN Clinical Nurse II - GI Procedures
$74K - $114K *
Advance patient care by delivering high-quality nursing services in a dynamic GI Procedures unit. Collaborate with a dedicated team to ensure optimal outcomes through effective assessment, planning, a...
1 week ago
Manager, Employee Relations - UNC SOM
$88K - $105K *
Champion employee relations by leading a team to enhance workplace culture, resolve complex issues, and ensure compliance with HR policies. Collaborate with leadership to foster positive relationships...
1 week ago
RN Clinical Nurse II - Children's Short Stay Unit
$71K - $100K *
Deliver exceptional pediatric nursing care in a dynamic unit, focusing on post-surgical recovery and observation. Collaborate with a multidisciplinary team to ensure quality outcomes for diverse patie...
1 week ago
RN Clinical Nurse II Emergency Room
$71K - $100K *
Empower patient care by delivering high-quality clinical nursing services. Collaborate with interdisciplinary teams to assess, plan, and implement effective care strategies in a dynamic hospital envir...
1 week ago
$99K *
Help us conduct MRI procedures and tests to acquire and analyze patient diagnostic data, ensuring safety and accuracy while maintaining high standards of care and technical proficiency in a collaborat...
1 week ago
Family Medicine Physician (MD/DO) - UNC Boylan Healthcare at North Hills
$180K - $220K *
Empower your career by providing comprehensive primary care to adults. Utilize advanced technology and preventive health strategies to enhance patient well-being while building lasting relationships i...
1 week ago
$88K - $105K *
Transform provider enrollment processes by leading a dedicated team, ensuring compliance, and driving continuous improvement to exceed organizational goals and enhance service quality...
1 week ago
Pediatric Neurologist (MD/DO) - UNC Health Children's
$180K - $220K *
Lead the charge in providing specialized pediatric neurology care, collaborating with a dynamic team to enhance clinical services and educational opportunities across Southeastern NC, while engaging i...
1 week ago
RN Clinical Nurse II- Cardiac Surgery Acute Care Day Shift
$71K - $100K *
Drive excellence in patient care within a dynamic Cardiovascular Acute Care Unit. Collaborate with interdisciplinary teams to deliver high-quality nursing services, ensuring optimal outcomes for patie...
1 week ago
Enterprise Account Executive-E-Invoice
$119K - $155K *
Unlock your potential by driving revenue through strategic sales of tax solutions. Collaborate with clients to tailor offerings, build relationships, and navigate complex organizations, ensuring enter...
1 week ago
Primary Care Physician (MD/DO) - Western North Carolina
$190K - $230K *
Join a team that's dedicated to providing exceptional primary care. Take ownership of patient health in a supportive environment, collaborating with seasoned professionals to enhance community well-be...
1 week ago
$115K - $127K *
Join a dynamic team to monitor oncology clinical trials, ensuring compliance and data integrity while supporting investigative sites throughout the trial lifecycle. Leverage your expertise in clinical...
1 week ago
$215K - $230K *
Transform compliance into actionable insights by bridging technical teams and auditors. Own your area of responsibility, enhance security measures, and drive automation in a multi-cloud environment wh...
1 week ago
$110K - $130K *
Join a team that's redefining organizational strategy and driving impactful solutions. As a Senior People Partner, you'll collaborate with leadership to align talent priorities with business outcomes...
1 week ago
Manager, Regional Sales - Specialty (Penn-Erie)
$149K - $187K *
Drive regional sales success by leading a team of Territory Sales Managers, fostering a culture of accountability and collaboration, and executing strategic initiatives to achieve performance targets...
1 week ago
Customer Success Engineer - LATAM
$100K - $200K *
Join a team that's dedicated to enhancing customer success through technical expertise. You'll build strong relationships with enterprise clients, guiding them in adopting our products and ensuring th...
Reposted 1 week ago
Operations Support Manager-Int Supply
$80K - $95K *
Transform enterprise-wide project initiatives by collaborating across functions, ensuring timely and budget-compliant delivery while enhancing stakeholder satisfaction and driving continuous improveme...
1 week ago
Rehab Director SNF PT PTA OT OTA SLP
$80K - $95K *
Champion rehabilitation excellence by overseeing treatment schedules, monitoring productivity, and ensuring compliance with professional guidelines while fostering communication with families and main...
1 week ago
Associate Director, Regulatory Project Management
$136K - $220K *
Unlock project management excellence in Global Regulatory Affairs, driving timelines and compliance for drug submissions. Collaborate cross-functionally to ensure accurate documentation and effective...
Reposted 1 week ago
Senior Manager, Clinical Conduct
$90K - $110K *
Empower cross-functional teams to drive the Future of Medicine initiatives, ensuring scalable processes and compliance while enhancing patient safety and experience through strategic planning and exec...
1 week ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.