Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,816

Sort By: Relevance

$230K - $285K *

Transform your career by leading engineering excellence for a cutting-edge CRM platform. Drive strategy, architecture, and team growth while ensuring quality and security in a collaborative environmen...

United StatesRemote

1 week ago

  •   11 - 15 years exp.  •   Business Services

$183K - $216K *

Innovate the analytical roadmap for ranking and relevance, collaborating with cross-functional teams to enhance user engagement and advertiser outcomes while driving long-term platform economics and s...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$90K - $110K *

Join our interdisciplinary healthcare team to provide high-quality, cost-effective patient care as an Advanced Practice Provider. Collaborate with physicians, lead initiatives, and enhance patient out...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$124K - $186K *

Accelerate enterprise adoption of our AI-powered DevSecOps platform by guiding large organizations through complex software delivery transformations, ensuring they achieve long-term value and success...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$115K - $165K *

Shape the future of patient care as a Clinical Pharmacist Practitioner, collaborating with a multidisciplinary team to manage advanced heart failure therapies and enhance patient outcomes through educ...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Transform the future of surgical education by leading the Surgical Proficiency Laboratory. Drive innovative curricula, manage operations, and secure funding to enhance training for residents and fello...

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$210K - $250K *

Transform patient care by delivering exceptional nocturnal medical services. Leverage your expertise in internal medicine to diagnose and treat patients during night shifts, ensuring high-quality heal...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Lead a dynamic team driving technical innovation and improving enterprise data quality. Collaborate across departments to enhance data governance, reporting, and analytics while implementing strategic...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$110K - $130K *

Join a team that's driving technical innovation and enhancing enterprise data management. Lead and mentor associates while overseeing data quality and governance initiatives to align with strategic or...

Reposted 1 week ago

  •   8 - 10 years exp.  •   Finance & Insurance

$95K - $115K *

Drive provider network excellence by managing data integrity, overseeing contract configurations, and leading cross-functional teams to enhance operational efficiency and compliance in a dynamic TPA e...

RemoteRemote

1 week ago

  •   5 - 7 years exp.  •   Healthcare

$100K *

Engage in a year-long fellowship for recent law school graduates, assisting with pivotal public interest cases while developing skills in legal research, writing, and strategic litigation, alongside e...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Legal & Accounting

$110K - $130K *

Lead the charge in optimizing drug library implementations for smart infusion pumps, collaborating with healthcare teams to enhance medication safety and workflow efficiency across mid- to large-sized...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$105K - $110K *

Drive your career forward as a CDL-A Car Haul Truck Driver, enjoying competitive pay, comprehensive benefits, and the opportunity for growth through training and support in a dedicated account with st...

1 week ago

  •   Less than 5 years exp.  •   Transportation

$368K - $477K *

Pioneer cloud growth by leading a global team to cultivate strategic partnerships with hyperscalers. Drive revenue through innovative go-to-market strategies and enhance cloud migration solutions acro...

1 week ago

  •   11 - 15 years exp.  •   Enterprise Technology

$125K - $150K *

Optimize business growth by identifying new opportunities and building relationships with key stakeholders. Leverage solution-selling expertise to drive enterprise sales and achieve revenue targets wh...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$88K - $105K *

Empower growth by leveraging technical sales expertise to enhance customer relationships and promote innovative life sciences products, driving advancements in research and manufacturing capabilities...

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$93K - $187K *

Champion innovative solutions in government healthcare consulting, managing client engagements and delivering strategic insights. Leverage your actuarial expertise to drive impactful analyses and fost...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$150K - $160K *

Elevate workplace safety by partnering with clients to assess programs, identify risks, and implement strategies that reduce injuries. Leverage your expertise in industrial hygiene and compliance to f...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$68K - $114K *

Lead the charge in delivering tailored insurance solutions for small businesses. Collaborate with brokers and carriers to ensure optimal coverage, while driving growth and maintaining strong relations...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$131K - $180K *

Lead the charge in advancing safety standards as you manage interdisciplinary engineering projects and a high-performing team, ensuring strategies align with organizational goals and technical excelle...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Aerospace & Defense

$64K - $97K *

Advance audit practices by executing comprehensive evaluations, ensuring adherence to established standards. Foster strong stakeholder communication while identifying operational efficiencies and enha...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$115K - $173K *

Empower your career by managing complex loan workouts, negotiating terms, and guiding teams. Utilize your expertise in financial analysis and communication to drive successful outcomes for challenging...

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$79K - $127K *

Lead the charge in developing innovative Salesforce solutions that drive analytics and support business objectives. Collaborate with teams to deliver high-quality applications while ensuring alignment...

1 week ago

  •   Less than 5 years exp.  •   Finance & Insurance

$190K *

Optimize engineering services by leading DevOps and SRE teams, enhancing CI/CD processes, and ensuring data governance. Drive operational excellence and security while fostering a collaborative enviro...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$275K - $330K *

Transform cloud services architecture and lead innovative design initiatives. As a Principal Engineer, you'll drive technical direction, optimize data models, and mentor teams to enhance software deli...

RemoteRemote

1 week ago

  •   11 - 15 years exp.  •   Hospitals & Medical Centers

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.