Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

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1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,816

Sort By: Relevance

$160K - $192K *

Join a team that's driving commercial success by engaging healthcare providers, building relationships, and supporting innovative therapies. Your expertise will be crucial in executing business plans...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$85K - $110K *

Develop engaging, platform-native content that connects healthcare insights with audiences. Collaborate with teams to create innovative social media strategies, transforming complex information into r...

United StatesRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$85K - $100K *

Transform product initiatives by driving the Product Development Lifecycle, ensuring clarity and momentum across functions while empowering teams to focus on their expertise and decisions...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Education, Government & Non-Profit

$71K - $100K *

Join a team that's dedicated to providing compassionate care for patients recovering from life-changing illnesses. Collaborate with an interdisciplinary unit to support patient independence and enhanc...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$95K - $115K *

Elevate your career by joining a dynamic surgical team, providing comprehensive care in a collaborative environment. Gain broad exposure to general surgery while enjoying a supportive atmosphere and s...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$120K - $145K *

Explore the opportunity to manage and evolve complex multi-prem platform architecture. Collaborate with engineering teams, ensuring operational excellence across diverse environments while leveraging...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Information Technology

$110K - $130K *

Optimize program delivery by leading complex projects from proposal to execution. Drive cross-functional collaboration, manage budgets, and ensure customer commitments are met while mentoring junior p...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Aerospace & Defense

$100K - $120K *

Join a dynamic team to build and execute innovative ABM programs that engage and grow strategic accounts. Collaborate with sales and marketing to create personalized experiences that drive pipeline an...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$95K - $115K *

Join a dynamic team as you drive client success in healthcare IT. Collaborate with cross-functional teams to enhance client experiences and optimize product usage, ensuring satisfaction and retention...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$185K - $230K *

Elevate community access to innovative therapies by developing strategic reimbursement solutions, collaborating with stakeholders, and ensuring compliance with healthcare regulations while managing co...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$110K - $130K *

Manage quality initiatives across product categories, ensuring compliance and operational excellence. Partner with teams to drive continuous improvement, mitigate risks, and enhance quality systems, a...

1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$130K - $190K *

Lead the Engineering Department to drive manufacturing excellence, enhance organizational capability, and achieve strategic objectives through effective planning, management, and continuous improvemen...

1 week ago

  •   Less than 5 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Join a team that's transforming digital marketing by driving data-driven campaigns. Lead a passionate group in delivering seamless customer experiences across multiple channels while optimizing for pe...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Food & Beverages

$178K - $261K *

Lead the charge in shaping a secure and seamless identity experience for millions globally. Drive strategy for authentication, account management, and recovery while collaborating across teams to prot...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$140K - $160K *

Drive new business development and revenue growth by leveraging professional networks and sales expertise to secure major client engagements and enhance executive relationships within Fortune 500 comp...

RemoteRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$150K - $220K *

Empower our team by leading the design of complex, data-rich workflows. Collaborate with cross-functional teams to enhance user experiences and establish scalable design patterns that drive innovation...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Finance & Insurance

$95K - $115K *

Unlock potential by optimizing asset reliability through data analysis and engineering principles. Collaborate with cross-functional teams to enhance maintenance strategies and drive reliability-focus...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$103K - $129K *

Drive operational excellence by overseeing cargo operations, ensuring safety compliance, and enhancing customer satisfaction. Lead a collaborative team to optimize efficiency and foster a performance...

1 week ago

  •   Less than 5 years exp.  •   Transportation

$205K - $240K *

Shape the future of oncology as a Senior Medical Science Liaison, creating impactful scientific engagement within hematology and oncology that enhances patient care. Collaborate with KOLs and cross-fu...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$101K - $154K *

Shape product strategy and commercialization efforts, ensuring alignment with market trends and customer needs. Drive product development, marketing initiatives, and cross-functional collaboration to...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$105K - $145K *

Lead the development and implementation of machine vision systems, driving quality inspection and process monitoring. Collaborate with cross-functional teams to enhance product performance and mentor...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$128K - $159K *

Pioneer innovative event strategies that enhance customer experiences globally. Lead the planning and execution of impactful marketing events, collaborating with cross-functional teams to drive engage...

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$91K - $116K *

Lead the charge in enhancing governance and risk management through comprehensive audits. Collaborate with teams to ensure compliance with standards while mentoring junior auditors and driving continu...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

$110K - $130K *

Lead the charge in complex H&S compliance projects while mentoring staff, managing client relationships, and ensuring the highest standards of safety and professionalism in a remote work environment...

United StatesRemote

Reposted 1 week ago

  •   11 - 15 years exp.  •   Technical Services

$91K - $116K *

Join a team that's dedicated to enhancing governance and risk management through comprehensive audits. This role involves developing audit programs, mentoring staff, and ensuring compliance with indus...

Morrisville, NCRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Energy & Utilities

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.