Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.
North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.
Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.
Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.
Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.
Average Salary: $114,816
Account Specialists (La Crosse, WI)
$160K - $192K *
Join a team that's driving commercial success by engaging healthcare providers, building relationships, and supporting innovative therapies. Your expertise will be crucial in executing business plans...
1 week ago
$85K - $110K *
Develop engaging, platform-native content that connects healthcare insights with audiences. Collaborate with teams to create innovative social media strategies, transforming complex information into r...
Reposted 1 week ago
$85K - $100K *
Transform product initiatives by driving the Product Development Lifecycle, ensuring clarity and momentum across functions while empowering teams to focus on their expertise and decisions...
1 week ago
RN Clinical Nurse II - Acute Inpatient Rehabilitation Unit
$71K - $100K *
Join a team that's dedicated to providing compassionate care for patients recovering from life-changing illnesses. Collaborate with an interdisciplinary unit to support patient independence and enhanc...
1 week ago
General Surgery Advanced Practice Provider (NP/PA) UNC Surgical Specialists at Goldsboro
$95K - $115K *
Elevate your career by joining a dynamic surgical team, providing comprehensive care in a collaborative environment. Gain broad exposure to general surgery while enjoying a supportive atmosphere and s...
1 week ago
$120K - $145K *
Explore the opportunity to manage and evolve complex multi-prem platform architecture. Collaborate with engineering teams, ensuring operational excellence across diverse environments while leveraging...
Reposted 1 week ago
$110K - $130K *
Optimize program delivery by leading complex projects from proposal to execution. Drive cross-functional collaboration, manage budgets, and ensure customer commitments are met while mentoring junior p...
1 week ago
Account Based Marketing (ABM) Manager
$100K - $120K *
Join a dynamic team to build and execute innovative ABM programs that engage and grow strategic accounts. Collaborate with sales and marketing to create personalized experiences that drive pipeline an...
1 week ago
Client Success Manager, Healthcare Revenue Cycle (West Coast candidates preferred!)
$95K - $115K *
Join a dynamic team as you drive client success in healthcare IT. Collaborate with cross-functional teams to enhance client experiences and optimize product usage, ensuring satisfaction and retention...
1 week ago
Field Reimburesement Manager - Pennsylvania
$185K - $230K *
Elevate community access to innovative therapies by developing strategic reimbursement solutions, collaborating with stakeholders, and ensuring compliance with healthcare regulations while managing co...
1 week ago
Sr Manager Quality - Performance & Improvement
$110K - $130K *
Manage quality initiatives across product categories, ensuring compliance and operational excellence. Partner with teams to drive continuous improvement, mitigate risks, and enhance quality systems, a...
1 week ago
$130K - $190K *
Lead the Engineering Department to drive manufacturing excellence, enhance organizational capability, and achieve strategic objectives through effective planning, management, and continuous improvemen...
1 week ago
Senior Manager Campaign Operations
$110K - $130K *
Join a team that's transforming digital marketing by driving data-driven campaigns. Lead a passionate group in delivering seamless customer experiences across multiple channels while optimizing for pe...
Reposted 1 week ago
Principal Product Manager, Identity & Trust
$178K - $261K *
Lead the charge in shaping a secure and seamless identity experience for millions globally. Drive strategy for authentication, account management, and recovery while collaborating across teams to prot...
1 week ago
Enterprise Sales, Commercial Practice
$140K - $160K *
Drive new business development and revenue growth by leveraging professional networks and sales expertise to secure major client engagements and enhance executive relationships within Fortune 500 comp...
Reposted 1 week ago
Lead Product Designer (United States or Canada, Remote)
$150K - $220K *
Empower our team by leading the design of complex, data-rich workflows. Collaborate with cross-functional teams to enhance user experiences and establish scalable design patterns that drive innovation...
1 week ago
Mechanical Reliability Engineer
$95K - $115K *
Unlock potential by optimizing asset reliability through data analysis and engineering principles. Collaborate with cross-functional teams to enhance maintenance strategies and drive reliability-focus...
1 week ago
$103K - $129K *
Drive operational excellence by overseeing cargo operations, ensuring safety compliance, and enhancing customer satisfaction. Lead a collaborative team to optimize efficiency and foster a performance...
1 week ago
$205K - $240K *
Shape the future of oncology as a Senior Medical Science Liaison, creating impactful scientific engagement within hematology and oncology that enhances patient care. Collaborate with KOLs and cross-fu...
Reposted 1 week ago
$101K - $154K *
Shape product strategy and commercialization efforts, ensuring alignment with market trends and customer needs. Drive product development, marketing initiatives, and cross-functional collaboration to...
1 week ago
$105K - $145K *
Lead the development and implementation of machine vision systems, driving quality inspection and process monitoring. Collaborate with cross-functional teams to enhance product performance and mentor...
1 week ago
Senior Global Event Marketing Manager
$128K - $159K *
Pioneer innovative event strategies that enhance customer experiences globally. Lead the planning and execution of impactful marketing events, collaborating with cross-functional teams to drive engage...
1 week ago
Internal Auditor II (Full-time Remote, North Carolina Based)
$91K - $116K *
Lead the charge in enhancing governance and risk management through comprehensive audits. Collaborate with teams to ensure compliance with standards while mentoring junior auditors and driving continu...
Reposted 1 week ago
Senior Health and Safety Compliance Specialist
$110K - $130K *
Lead the charge in complex H&S compliance projects while mentoring staff, managing client relationships, and ensuring the highest standards of safety and professionalism in a remote work environment...
Reposted 1 week ago
Internal Auditor II (Full-time Remote, North Carolina Based)
$91K - $116K *
Join a team that's dedicated to enhancing governance and risk management through comprehensive audits. This role involves developing audit programs, mentoring staff, and ensuring compliance with indus...
Reposted 1 week ago
What types of $100K+ jobs can I find in North Carolina?
North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.
Which North Carolina cities have professional job opportunities?
You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.
Are the jobs on this page vetted?
Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.
How can I find a specific type of job in North Carolina?
Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.
Do all North Carolina jobs on Ladders pay at least $100,000?
Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.