Explore $100K+ Jobs in North Carolina

Discover vetted professional jobs paying $100,000 or more across North Carolina. From the Research Triangle to Charlotte and beyond, find career opportunities with employers seeking experienced talent in a range of industries. Browse current openings and explore roles that match your skills, experience, and career goals.

Professional Opportunities Across the State

North Carolina offers a diverse economy, with opportunities in technology, financial services, healthcare, life sciences, manufacturing, and other professional fields. Job availability varies by location and employer, so search across the state to find positions that fit your background and preferred work arrangement.

Explore North Carolina's Major Job Markets

Look for roles in Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, Winston-Salem, and other North Carolina communities. The Research Triangle is known for technology, life sciences, and research organizations, while Charlotte is a major center for banking and business. Opportunities are also available in cities and communities throughout the state.

Find a Role That Fits Your Experience

Use Ladders to explore vetted opportunities with salaries of $100,000 or more. Review each listing for qualifications, responsibilities, location, and compensation details. Search by job title, industry, or city, and refine your search to focus on opportunities aligned with your professional experience.

Advance Your Career in North Carolina

Whether you are planning your next move or considering a new location, Ladders can help you discover high-paying professional jobs in North Carolina. Browse the latest listings and take the next step toward a role that supports your career ambitions.

Remote
caret down
Compensation
caret down
Position Level
caret down
Time Posted
caret down
Industries
caret down
Locations
caret down
More
1
caret down
1,000+

Jobs in North Carolina

Average Salary in USD

Average Salary: $114,657

Sort By: Relevance

$130K - $140K *

Advance your career by implementing and enhancing health and safety programs across the West Coast. Collaborate with leaders and teams to ensure compliance, conduct audits, and foster a culture of saf...

RemoteRemote

1 week ago

  •   8 - 10 years exp.  •   Technical Services

$210K - $250K *

Lead strategic business development initiatives, driving deal execution and relationship management with senior health plan stakeholders. Shape growth strategies and negotiate value-based care contrac...

United StatesRemote

1 week ago

  •   8 - 10 years exp.  •   Hospitals & Medical Centers

$95K - $110K *

Drive inventory efficiency across a multi-site distribution network. Shape SAP planning strategies to optimize stock levels, enhance service delivery, and collaborate with cross-functional teams for c...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$110K - $130K *

Join a team that's redefining customer engagement by leveraging advanced platform capabilities. Collaborate with sales and technical teams to deliver tailored solutions, driving value and enhancing th...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Business Services

$100K - $130K *

Elevate your career as a Commercial HVAC Estimator overseeing project estimates, collaborating with stakeholders, and driving success through precision and analysis in mechanical construction...

Reposted 1 week ago

  •   5 - 7 years exp.  •   Business Services

$110K - $130K *

Join a team that's redefining People partnerships by driving strategic initiatives and enhancing organizational effectiveness. Leverage your expertise to support business leaders and foster a culture...

1 week ago

  •   8 - 10 years exp.  •   Information Technology

$135K - $202K *

Elevate patient engagement by educating NF1 and HPP communities through tailored outreach, collaboration with advocacy groups, and impactful events, ensuring comprehensive support throughout their tre...

1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$81K - $108K *

Drive operational excellence as a key financial link in 3PL logistics. Collaborate with site leaders to enhance billing accuracy, track performance metrics, and strengthen client relationships while s...

1 week ago

  •   Less than 5 years exp.  •   Business Services

$80K - $95K *

Transform client challenges into impactful digital marketing solutions. Partner closely with sales teams to drive revenue growth across platforms, leveraging your expertise to create tailored strategi...

Reposted 1 week ago

  •   Less than 5 years exp.  •   Media

$270K - $290K *

Join a team that's shaping innovative brand strategies for rare epilepsy programs. Lead marketing initiatives, drive launch readiness, and build a high-performing team to deliver impactful solutions f...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$75K - $105K *

Collaborate with clients to enhance their social media strategies using healthcare insights, data-driven execution, and creative content development for multi-channel success. This role demands a proa...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Pharmaceuticals & Biotech

$95K - $110K *

Shape innovative marketing strategies as a Senior Art Director, leading creative projects that align with client objectives. Collaborate with teams to deliver impactful visual content, driving busines...

RemoteRemote

Reposted 1 week ago

  •   Less than 5 years exp.  •   Pharmaceuticals & Biotech

$105K - $150K *

Transform healthcare insights by leading client engagements with real-world data. Drive business development and project delivery while building long-term client relationships in a dynamic, hybrid wor...

United StatesRemote

Reposted 1 week ago

  •   8 - 10 years exp.  •   Pharmaceuticals & Biotech

$108K - $138K *

Shape the future of our ERP transformation by leading a multi-year initiative, coordinating with diverse stakeholders and external partners to ensure successful implementation across Finance, HR, and...

1 week ago

  •   8 - 10 years exp.  •   Education, Government & Non-Profit

$135K - $160K *

The Director of Strategic Accounts is responsible for developing and closing business with Motive's largest prospects, primarily targeting Fortune 500 companies. This role involves building relationsh...

United StatesRemote

Reposted 1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$120K - $145K *

Drive impactful customer experiences by leading technical discovery, crafting compelling demos, and executing proof-of-value initiatives. Collaborate with sales to bridge technology and business value...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$110K - $130K *

Transform business performance by driving growth strategies and execution across global accounts. Collaborate with cross-functional teams to enhance customer success and services adoption, ensuring al...

1 week ago

  •   5 - 7 years exp.  •   Manufacturing & Automotive

$120K - $145K *

Architect impactful growth strategies by leading global channel marketing initiatives that drive partner engagement and pipeline acceleration. Collaborate across teams to translate complex strategies...

1 week ago

  •   8 - 10 years exp.  •   Manufacturing & Automotive

$100K - $115K *

Build strong client partnerships and drive growth by managing a portfolio of mid-sized employers. Collaborate cross-functionally to enhance engagement, retention, and revenue while delivering data-dri...

United StatesRemote

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$110K - $130K *

Transform application deployment by collaborating with teams to streamline processes, enhance automation, and ensure high-quality releases across environments while mentoring junior members and drivin...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Enterprise Technology

$160K - $200K *

Lead strategic state government affairs initiatives, shaping policy and advocacy efforts. Collaborate with diverse stakeholders to align organizational priorities with legislative agendas, ensuring im...

1 week ago

  •   11 - 15 years exp.  •   Healthcare

$130K - $155K *

Lead the charge in architecting innovative End User Computing solutions, collaborating with account teams and clients to drive strategy, deliver presentations, and enhance customer experiences while e...

United StatesRemote

1 week ago

  •   5 - 7 years exp.  •   Information Technology

$71K - $100K *

Join a team that's dedicated to delivering exceptional orthopedic care in a fast-paced environment. Collaborate with an interdisciplinary team to enhance patient recovery and outcomes while fostering...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$71K - $100K *

Join a team that's dedicated to providing exceptional care in a dynamic Emergency Department. Deliver direct and indirect nursing care for diverse patient needs, from minor injuries to critical cases...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

$117K - $160K *

Join our dynamic General Surgery Team as an Advanced Practice Provider, where you'll assist in the operating room, conduct inpatient rounds, and engage in clinic activities, all while collaborating wi...

1 week ago

  •   Less than 5 years exp.  •   Healthcare

Frequently Asked Questions (FAQ)

  • What types of $100K+ jobs can I find in North Carolina?question toggle

    North Carolina listings may include professional and leadership roles in technology, financial services, healthcare, life sciences, manufacturing, and other industries. Available jobs and compensation depend on the employer, location, and qualifications.

  • Which North Carolina cities have professional job opportunities?question toggle

    You can search for roles in cities including Charlotte, Raleigh, Durham, Chapel Hill, Greensboro, and Winston-Salem, as well as other communities across the state.

  • Are the jobs on this page vetted?question toggle

    Ladders hosts vetted professional job opportunities that pay $100,000 or more. Check individual listings for details about the employer, requirements, location, and compensation.

  • How can I find a specific type of job in North Carolina?question toggle

    Search by job title, industry, or city, then use available filters to narrow results by factors such as experience level or work arrangement.

  • Do all North Carolina jobs on Ladders pay at least $100,000?question toggle

    Ladders focuses on professional jobs paying $100,000 or more. Review each listing to confirm its compensation information and details.